Target Gene/Pathway Pathway / Gene
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Showing 1 to 10 of 20 entries
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID | ||||||||||||||||||||||||||||||||||||||||||||
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| 1 | TGF-beta signaling pathway 💬 10 genes, 20 drugs (DrugBank) and 55 diseases |
ACVR2A [1] ACVR2A 💬TGF-beta signaling pathway
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Sotatercept Sotatercept 💬TGF-beta signaling pathway
| Sotatercept | 086 [2] 86, 284 💬
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| 2 | TGF-beta signaling pathway 💬 10 genes, 20 drugs (DrugBank) and 55 diseases |
ACVR2A [2] ACVR2A, ACVR2B 💬
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Bimagrumab Bimagrumab 💬TGF-beta signaling pathway
| Bimagrumab | 015 [1] 15 💬2. TGF-beta signaling pathway
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| 3 | TGF-beta signaling pathway 💬 10 genes, 20 drugs (DrugBank) and 55 diseases |
ACVR2B [1] ACVR2B 💬TGF-beta signaling pathway
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Luspatercept Luspatercept 💬TGF-beta signaling pathway
| Luspatercept | 060 [1] 60 💬3. TGF-beta signaling pathway
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| 4 | TGF-beta signaling pathway 💬 10 genes, 20 drugs (DrugBank) and 55 diseases |
IFNG [1] IFNG 💬TGF-beta signaling pathway
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Emapalumab Emapalumab 💬TGF-beta signaling pathway
| Emapalumab | 049 [3] 49, 65, 107 💬
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| 5 | TGF-beta signaling pathway 💬 10 genes, 20 drugs (DrugBank) and 55 diseases |
IFNG [1] IFNG 💬TGF-beta signaling pathway
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Fontolizumab Fontolizumab 💬TGF-beta signaling pathway
| Fontolizumab | 046 [1] 46 💬5. TGF-beta signaling pathway
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| 6 | TGF-beta signaling pathway 💬 10 genes, 20 drugs (DrugBank) and 55 diseases |
RGMA [1] RGMA 💬TGF-beta signaling pathway
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Elezanumab Elezanumab 💬TGF-beta signaling pathway
| Elezanumab | 013 [1] 13 💬6. TGF-beta signaling pathway
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| 7 | TGF-beta signaling pathway 💬 10 genes, 20 drugs (DrugBank) and 55 diseases |
ROCK1 [1] ROCK1 💬TGF-beta signaling pathway
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Fasudil Fasudil 💬TGF-beta signaling pathway
| Fasudil | 002 [4] 2 , 5 , 7 , 51 💬
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| 8 | TGF-beta signaling pathway 💬 10 genes, 20 drugs (DrugBank) and 55 diseases |
SMAD7 [1] SMAD7 💬TGF-beta signaling pathway
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Mongersen Mongersen 💬TGF-beta signaling pathway
| Mongersen | 096 [2] 96, 97 💬
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| 9 | TGF-beta signaling pathway 💬 10 genes, 20 drugs (DrugBank) and 55 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
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Fresolimumab Fresolimumab 💬TGF-beta signaling pathway
| Fresolimumab | 051 [3] 51, 85, 222 💬
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| 10 | TGF-beta signaling pathway 💬 10 genes, 20 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬TGF-beta signaling pathway
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Adalimumab Adalimumab 💬TGF-beta signaling pathway
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬10. TGF-beta signaling pathway
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