Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY KEGG GENES KEGG DRUG DrugBank Disease ID
1 Yersinia infection 💬
 [5] CCL2, IL10, IL1B, IL6, TNF 💬 Pirfenidone 💬 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬
2 Yersinia infection 💬
 [1] CD4 💬 Zanolimumab 💬 Zanolimumab [1] 46 💬 💬
3 Yersinia infection 💬
 [1] IL1B 💬 Canakinumab 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬
4 Yersinia infection 💬
 [1] IL1B 💬 Gevokizumab 💬 Gevokizumab [4] 41, 50, 56, 269 💬 💬
5 Yersinia infection 💬
 [1] IL1B 💬 Rilonacept 💬 Rilonacept [4] 51, 106, 107, 266 💬 💬
6 Yersinia infection 💬
 [1] IL6 💬 Olokizumab 💬 Olokizumab [2] 46, 96 💬 💬
7 Yersinia infection 💬
 [1] IL6 💬 Siltuximab 💬 Siltuximab [2] 28, 331 💬 💬
8 Yersinia infection 💬
 [1] IL6 💬 Sirukumab 💬 Sirukumab [2] 41, 46 💬 💬
9 Yersinia infection 💬
 [2] IL6, TNF 💬 Pomalidomide 💬 Pomalidomide [5] 28, 51, 85, 227, 331 💬 💬
10 Yersinia infection 💬
 [1] ITGA4 💬 Abrilumab 💬 Abrilumab [2] 96, 97 💬 💬
11 Yersinia infection 💬
 [1] ITGA4 💬 Firategrast 💬 Firategrast [1] 13 💬 💬
12 Yersinia infection 💬
 [1] ITGA4 💬 Natalizumab 💬 Natalizumab [6] 13, 15, 25, 46, 63, 96 💬 💬
13 Yersinia infection 💬
 [1] ITGA4 💬 Vedolizumab 💬 Vedolizumab [3] 94, 96, 97 💬 💬
14 Yersinia infection 💬
 [2] LCK, SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬 💬
15 Yersinia infection 💬
 [2] LCK, SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬 💬
16 Yersinia infection 💬
 [2] MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib [1] 34 💬 💬
17 Yersinia infection 💬
 [2] MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib [1] 280 💬 💬
18 Yersinia infection 💬
 [2] MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib [1] 34 💬 💬
19 Yersinia infection 💬
 [2] MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib [1] 34 💬 💬
20 Yersinia infection 💬
 [2] MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib [4]  2 , 34, 279, 280 💬 💬
21 Yersinia infection 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 Losmapimod 💬 Losmapimod [2] 113, 222 💬 💬
22 Yersinia infection 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 Neflamapimod 💬 Neflamapimod [1]  8  💬 💬
23 Yersinia infection 💬
 [1] NFKB1 💬 Iguratimod 💬 Iguratimod [5] 46, 51, 53, 271, 300 💬 💬
24 Yersinia infection 💬
 [1] PIK3CA 💬 Alpelisib 💬 Alpelisib [1] 138 💬 💬
25 Yersinia infection 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 Leniolisib 💬 Leniolisib [2] 53, 65 💬 💬
26 Yersinia infection 💬
 [1] PIK3CD 💬 Parsaclisib 💬 Parsaclisib [3] 35, 53, 61 💬 💬
27 Yersinia infection 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬 💬
28 Yersinia infection 💬
 [2] ROCK1, ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬 💬
29 Yersinia infection 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [2] 51, 85 💬 💬
30 Yersinia infection 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬 💬
31 Yersinia infection 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬 💬
32 Yersinia infection 💬
 [1] TNF 💬 Adalimumab 💬 Adalimumab [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬
33 Yersinia infection 💬
 [1] TNF 💬 Certolizumab pegol 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬
34 Yersinia infection 💬
 [1] TNF 💬 Etanercept 💬 Etanercept [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 💬
35 Yersinia infection 💬
 [1] TNF 💬 Golimumab 💬 Golimumab [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 💬
36 Yersinia infection 💬
 [1] TNF 💬 Infliximab 💬 Infliximab [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬
37 Yersinia infection 💬
 [1] TNF 💬 Lenalidomide 💬 Lenalidomide [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 💬
38 Yersinia infection 💬
 [1] TNF 💬 Ozoralizumab 💬 Ozoralizumab [1] 46 💬 💬
39 Yersinia infection 💬
 [1] TNF 💬 Pegsunercept 💬 Pegsunercept [1] 46 💬 💬
40 Yersinia infection 💬
 [1] TNF 💬 Thalidomide 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬