Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY KEGG GENES KEGG DRUG DrugBank Disease ID
1 Hepatitis B 💬
 [1] BCL2 💬 Venetoclax 💬 Venetoclax [1] 28 💬 💬
2 Hepatitis B 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬 💬
3 Hepatitis B 💬
 [2] BRAF, RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬 💬
4 Hepatitis B 💬
 [1] CASP9 💬 Rimiducid 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬 💬
5 Hepatitis B 💬
 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 Rontalizumab 💬 Rontalizumab [1] 49 💬 💬
6 Hepatitis B 💬
 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 Sifalimumab 💬 Sifalimumab [1] 49 💬 💬
7 Hepatitis B 💬
 [1] IFNAR1 💬 Anifrolumab 💬 Anifrolumab [3] 46, 49, 53 💬 💬
8 Hepatitis B 💬
 [1] IFNAR1 💬 Interferon alfa 💬 Interferon alfa [6] 13, 25, 26, 28, 56, 96 💬 💬
9 Hepatitis B 💬
 [1] IFNAR1 💬 Interferon alfa-2a 💬 Interferon alfa-2a [1] 56 💬 💬
10 Hepatitis B 💬
 [1] IFNAR1 💬 Interferon alfa-2b 💬 Interferon alfa-2b [2] 25, 34 💬 💬
11 Hepatitis B 💬
 [1] IFNAR1 💬 Interferon beta-1a 💬 Interferon beta-1a [4] 13, 26, 96, 97 💬 💬
12 Hepatitis B 💬
 [1] IFNAR1 💬 Interferon beta-1b 💬 Interferon beta-1b [1] 13 💬 💬
13 Hepatitis B 💬
 [1] IFNAR1 💬 Peginterferon beta-1a 💬 Peginterferon beta-1a [1] 13 💬 💬
14 Hepatitis B 💬
 [1] IL6 💬 Olokizumab 💬 Olokizumab [2] 46, 96 💬 💬
15 Hepatitis B 💬
 [1] IL6 💬 Siltuximab 💬 Siltuximab [2] 28, 331 💬 💬
16 Hepatitis B 💬
 [1] IL6 💬 Sirukumab 💬 Sirukumab [2] 41, 46 💬 💬
17 Hepatitis B 💬
 [2] IL6, TNF 💬 Pirfenidone 💬 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬
18 Hepatitis B 💬
 [2] IL6, TNF 💬 Pomalidomide 💬 Pomalidomide [5] 28, 51, 85, 227, 331 💬 💬
19 Hepatitis B 💬
 [1] JAK1 💬 Abrocitinib 💬 Abrocitinib [1] 84 💬 💬
20 Hepatitis B 💬
 [1] JAK1 💬 Filgotinib 💬 Filgotinib [6] 46, 53, 96, 97, 222, 271 💬 💬
21 Hepatitis B 💬
 [1] JAK1 💬 Itacitinib 💬 Itacitinib [4] 46, 51, 97, 228 💬 💬
22 Hepatitis B 💬
 [1] JAK1 💬 Upadacitinib 💬 Upadacitinib [8] 40, 41, 46, 49, 96, 97, 107, 271 💬 💬
23 Hepatitis B 💬
 [2] JAK1, JAK2 💬 Baricitinib 💬 Baricitinib [13]  2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬
24 Hepatitis B 💬
 [2] JAK1, JAK2 💬 Ruxolitinib 💬 Ruxolitinib [3] 60, 65, 228 💬 💬
25 Hepatitis B 💬
 [3] JAK1, JAK2, JAK3 💬 Peficitinib 💬 Peficitinib [1] 46 💬 💬
26 Hepatitis B 💬
 [4] JAK1, JAK2, JAK3, TYK2 💬 Tofacitinib 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬
27 Hepatitis B 💬
 [2] MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib [1] 34 💬 💬
28 Hepatitis B 💬
 [2] MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib [1] 280 💬 💬
29 Hepatitis B 💬
 [2] MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib [1] 34 💬 💬
30 Hepatitis B 💬
 [2] MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib [1] 34 💬 💬
31 Hepatitis B 💬
 [2] MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib [4]  2 , 34, 279, 280 💬 💬
32 Hepatitis B 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 Losmapimod 💬 Losmapimod [2] 113, 222 💬 💬
33 Hepatitis B 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 Neflamapimod 💬 Neflamapimod [1]  8  💬 💬
34 Hepatitis B 💬
 [1] NFKB1 💬 Iguratimod 💬 Iguratimod [5] 46, 51, 53, 271, 300 💬 💬
35 Hepatitis B 💬
 [1] PIK3CA 💬 Alpelisib 💬 Alpelisib [1] 138 💬 💬
36 Hepatitis B 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 Leniolisib 💬 Leniolisib [2] 53, 65 💬 💬
37 Hepatitis B 💬
 [1] PIK3CD 💬 Parsaclisib 💬 Parsaclisib [3] 35, 53, 61 💬 💬
38 Hepatitis B 💬
 [1] PRKCB 💬 Enzastaurin 💬 Enzastaurin [1] 168 💬 💬
39 Hepatitis B 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬 💬
40 Hepatitis B 💬
 [1] SLC10A1 💬 Maralixibat 💬 Maralixibat [3] 296, 297, 338 💬 💬
41 Hepatitis B 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬 💬
42 Hepatitis B 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬 💬
43 Hepatitis B 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬 💬
44 Hepatitis B 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬 💬
45 Hepatitis B 💬
 [3] TGFB1, TGFB2, TGFB3 💬 Fresolimumab 💬 Fresolimumab [3] 51, 85, 222 💬 💬
46 Hepatitis B 💬
 [1] TNF 💬 Adalimumab 💬 Adalimumab [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬
47 Hepatitis B 💬
 [1] TNF 💬 Certolizumab pegol 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬
48 Hepatitis B 💬
 [1] TNF 💬 Etanercept 💬 Etanercept [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 💬
49 Hepatitis B 💬
 [1] TNF 💬 Golimumab 💬 Golimumab [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 💬
50 Hepatitis B 💬
 [1] TNF 💬 Infliximab 💬 Infliximab [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬
51 Hepatitis B 💬
 [1] TNF 💬 Lenalidomide 💬 Lenalidomide [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 💬
52 Hepatitis B 💬
 [1] TNF 💬 Ozoralizumab 💬 Ozoralizumab [1] 46 💬 💬
53 Hepatitis B 💬
 [1] TNF 💬 Pegsunercept 💬 Pegsunercept [1] 46 💬 💬
54 Hepatitis B 💬
 [1] TNF 💬 Thalidomide 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬
55 Hepatitis B 💬
 [1] TYK2 💬 Deucravacitinib 💬 Deucravacitinib [3] 49, 96, 97 💬 💬