Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 ODC1 3件: Arginine and proline metabolism, Glutathione metabolism, Metabolic pathways D07883 Eflornithine 1件: 65
2 OPRD1 3件: cGMP-PKG signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction D05111 Nalmefene 1件: 6
3 OPRD1 3件: cGMP-PKG signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction D05113 Naltrexone 13件: 6, 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226
4 OPRD1 3件: cGMP-PKG signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction D05312 Oxycodone 5件: 6, 13, 70, 226, 298
5 OPRD1 3件: cGMP-PKG signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction D08144 Loperamide 2件: 13, 97
6 OPRD1 3件: cGMP-PKG signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction D08246 Nalbuphine 1件: 85
7 OPRD1 3件: cGMP-PKG signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction D08249 Naloxone 2件: 6, 226
8 OPRK1 1件: Neuroactive ligand-receptor interaction D00838 Dezocine 1件: 46
9 OPRK1 1件: Neuroactive ligand-receptor interaction D05111 Nalmefene 1件: 6
10 OPRK1 1件: Neuroactive ligand-receptor interaction D05113 Naltrexone 13件: 6, 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226
11 OPRK1 1件: Neuroactive ligand-receptor interaction D05312 Oxycodone 5件: 6, 13, 70, 226, 298
12 OPRK1 1件: Neuroactive ligand-receptor interaction D07132 Buprenorphine 2件: 46, 70
13 OPRK1 1件: Neuroactive ligand-receptor interaction D08144 Loperamide 2件: 13, 97
14 OPRK1 1件: Neuroactive ligand-receptor interaction D08246 Nalbuphine 1件: 85
15 OPRK1 1件: Neuroactive ligand-receptor interaction D08249 Naloxone 2件: 6, 226
16 OPRK1 1件: Neuroactive ligand-receptor interaction D08639 Trimebutine 1件: 51
17 OPRM1 3件: Neuroactive ligand-receptor interaction, Estrogen signaling pathway, Morphine addiction D00320 Fentanyl 3件: 46, 70, 215
18 OPRM1 3件: Neuroactive ligand-receptor interaction, Estrogen signaling pathway, Morphine addiction D00838 Dezocine 1件: 46
19 OPRM1 3件: Neuroactive ligand-receptor interaction, Estrogen signaling pathway, Morphine addiction D05111 Nalmefene 1件: 6
20 OPRM1 3件: Neuroactive ligand-receptor interaction, Estrogen signaling pathway, Morphine addiction D05113 Naltrexone 13件: 6, 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226
21 OPRM1 3件: Neuroactive ligand-receptor interaction, Estrogen signaling pathway, Morphine addiction D05312 Oxycodone 5件: 6, 13, 70, 226, 298
22 OPRM1 3件: Neuroactive ligand-receptor interaction, Estrogen signaling pathway, Morphine addiction D05938 Sufentanil 2件: 70, 280
23 OPRM1 3件: Neuroactive ligand-receptor interaction, Estrogen signaling pathway, Morphine addiction D07132 Buprenorphine 2件: 46, 70
24 OPRM1 3件: Neuroactive ligand-receptor interaction, Estrogen signaling pathway, Morphine addiction D07831 Dihydrocodeine 1件: 310
25 OPRM1 3件: Neuroactive ligand-receptor interaction, Estrogen signaling pathway, Morphine addiction D08047 Hydromorphone 1件: 70
26 OPRM1 3件: Neuroactive ligand-receptor interaction, Estrogen signaling pathway, Morphine addiction D08144 Loperamide 2件: 13, 97
27 OPRM1 3件: Neuroactive ligand-receptor interaction, Estrogen signaling pathway, Morphine addiction D08233 Morphine 5件: 36, 46, 70, 85, 86
28 OPRM1 3件: Neuroactive ligand-receptor interaction, Estrogen signaling pathway, Morphine addiction D08246 Nalbuphine 1件: 85
29 OPRM1 3件: Neuroactive ligand-receptor interaction, Estrogen signaling pathway, Morphine addiction D08249 Naloxone 2件: 6, 226
30 OPRM1 3件: Neuroactive ligand-receptor interaction, Estrogen signaling pathway, Morphine addiction D08323 Oxymorphone 1件: 70
31 OPRM1 3件: Neuroactive ligand-receptor interaction, Estrogen signaling pathway, Morphine addiction D08473 Remifentanil 2件: 6, 70
32 OPRM1 3件: Neuroactive ligand-receptor interaction, Estrogen signaling pathway, Morphine addiction D08623 Tramadol 5件: 46, 70, 78, 226, 271
33 OPRM1 3件: Neuroactive ligand-receptor interaction, Estrogen signaling pathway, Morphine addiction D08639 Trimebutine 1件: 51
34 OXTR 4件: Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway D00089 Oxytocin 7件: 6, 72, 127, 168, 193, 206, 226
35 OXTR 4件: Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway D03008 Atosiban 1件: 118