Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	CDK4	28件: Endocrine resistance, Cell cycle, p53 signaling pathway, PI3K-Akt signaling pathway, Cellular s ...	D10688	Abemaciclib	1件: 34
2	CDK6	23件: Cell cycle, p53 signaling pathway, PI3K-Akt signaling pathway, Cellular senescence, Cushing syn ...	D10688	Abemaciclib	1件: 34
3	CD52	-	D02802	Alemtuzumab	22件: 13, 15, 19, 20, 36, 43, 44, 46, 49, 51, 60, 62, 63, 65, 85, 96, 164, 234, 283, 284, 285, 326
4	CETP	1件: Cholesterol metabolism	D08855	Anacetrapib	1件: 79
5	CTSC	2件: Lysosome, Apoptosis	D12120	Brensocatib	1件: 299
6	CYSLTR1	2件: Calcium signaling pathway, Neuroactive ligand-receptor interaction	D01385	Ibudilast	2件: 2, 13
7	CYSLTR1	2件: Calcium signaling pathway, Neuroactive ligand-receptor interaction	D06659	Tipelukast	1件: 85
8	CYSLTR1	2件: Calcium signaling pathway, Neuroactive ligand-receptor interaction	D08229	Montelukast	8件: 6, 13, 46, 61, 63, 85, 98, 228
9	CFTR	8件: ABC transporters, cAMP signaling pathway, AMPK signaling pathway, Tight junction, Gastric acid s ...	D09916	Ivacaftor	1件: 299
10	CFTR	8件: ABC transporters, cAMP signaling pathway, AMPK signaling pathway, Tight junction, Gastric acid s ...	D10134	Lumacaftor	1件: 299

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