Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	LILRA4	2件: Osteoclast differentiation, B cell receptor signaling pathway	D11778	Daxdilimab	2件: 49, 50
2	LCK	10件: NF-kappa B signaling pathway, Osteoclast differentiation, Natural killer cell mediated cytotoxi ...	D03658	Dasatinib	2件: 51, 85
3	LCK	10件: NF-kappa B signaling pathway, Osteoclast differentiation, Natural killer cell mediated cytotoxi ...	D06414	Dasatinib	2件: 51, 85
4	LEPR	6件: Cytokine-cytokine receptor interaction, Neuroactive ligand-receptor interaction, AMPK signaling ...	D05014	Metreleptin	1件: 265
5	LIPA	3件: Steroid biosynthesis, Lysosome, Cholesterol metabolism	D10377	Sebelipase alfa	1件: 19
6	LTA	7件: Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine rec ...	D00742	Etanercept	16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285
7	LTA	7件: Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine rec ...	D10187	Pateclizumab	1件: 46
8	LTB	3件: Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Rheumatoid arthritis	D08866	Baminercept	4件: 13, 46, 53, 97
9	LINGO1	-	D11767	Opicinumab	1件: 13

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