Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	BRD4	-	D11131	Apabetalone	1件: 86
2	BCL2	43件: EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Platinum drug resistance, NF-k ...	D10679	Venetoclax	1件: 28
3	BRD2	-	D11131	Apabetalone	1件: 86
4	BRAF	44件: EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, MAPK signaling pathway, ErbB s ...	D08524	Sorafenib	2件: 34, 86
5	BRAF	44件: EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, MAPK signaling pathway, ErbB s ...	D10064	Dabrafenib	1件: 34
6	BRDT	-	D11131	Apabetalone	1件: 86
7	BTK	7件: NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, B cell receptor s ...	D10223	Ibrutinib	3件: 28, 60, 61
8	BTK	7件: NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, B cell receptor s ...	D10893	Acalabrutinib	2件: 46, 61
9	BTK	7件: NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, B cell receptor s ...	D11422	Zanubrutinib	5件: 13, 63, 222, 300, 331
10	BTK	7件: NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, B cell receptor s ...	D11457	Fenebrutinib	1件: 13

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