Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	PARP2	2件: Base excision repair, Apoptosis	D09730	Olaparib	2件: 86, 285
2	PDE10A	4件: Purine metabolism, Metabolic pathways, cAMP signaling pathway, Morphine addiction	D00227	Aminophylline	1件: 63
3	PDE10A	4件: Purine metabolism, Metabolic pathways, cAMP signaling pathway, Morphine addiction	D00371	Theophylline	2件: 236, 299
4	PDE10A	4件: Purine metabolism, Metabolic pathways, cAMP signaling pathway, Morphine addiction	D06103	Theophylline	2件: 236, 299
5	PDE10A	4件: Purine metabolism, Metabolic pathways, cAMP signaling pathway, Morphine addiction	D07546	Bucladesine	1件: 246
6	PDE10A	4件: Purine metabolism, Metabolic pathways, cAMP signaling pathway, Morphine addiction	D07961	Flavoxate	1件: 226
7	PARP1	5件: Base excision repair, NF-kappa B signaling pathway, Apoptosis, Necroptosis, Diabetic cardiomyopa ...	D09730	Olaparib	2件: 86, 285
8	POLA2	1件: DNA replication	D03546	Clofarabine	5件: 19, 20, 60, 234, 326
9	PCSK9	1件: Cholesterol metabolism	D10335	Alirocumab	1件: 79
10	PCSK9	1件: Cholesterol metabolism	D10557	Evolocumab	2件: 79, 222

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