Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	DDC	9件: Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Metabolic pathways, Seroto ...	D00558	Carbidopa	7件: 6, 13, 17, 90, 140, 164, 201
2	DDC	9件: Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Metabolic pathways, Seroto ...	D03082	Benserazide	1件: 6
3	DHFR	5件: One carbon pool by folate, Folate biosynthesis, Metabolic pathways, Biosynthesis of cofactors, A ...	D00142	Methotrexate	38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, ...
4	DHODH	3件: Pyrimidine metabolism, Metabolic pathways, Biosynthesis of cofactors	D00749	Leflunomide	12件: 11, 40, 46, 49, 53, 66, 107, 162, 224, 270, 271, 300
5	DHODH	3件: Pyrimidine metabolism, Metabolic pathways, Biosynthesis of cofactors	D10172	Teriflunomide	3件: 13, 25, 26
6	DMD	4件: Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyop ...	D09900	Eteplirsen	1件: 113
7	DMD	4件: Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyop ...	D10114	Drisapersen	1件: 113
8	DMD	4件: Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyop ...	D11528	Viltolarsen	1件: 113
9	DMD	4件: Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyop ...	D11707	Golodirsen	1件: 113
10	DMD	4件: Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyop ...	D11988	Casimersen	1件: 113

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