Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	MASP2	3件: Complement and coagulation cascades, Staphylococcus aureus infection, Coronavirus disease - COVI ...	D11531	Narsoplimab	4件: 64, 66, 109, 222
2	MAPK14	62件: Endocrine resistance, MAPK signaling pathway, Rap1 signaling pathway, FoxO signaling pathway, S ...	D09639	Losmapimod	2件: 113, 222
3	MAPK14	62件: Endocrine resistance, MAPK signaling pathway, Rap1 signaling pathway, FoxO signaling pathway, S ...	D10959	Neflamapimod	1件: 8
4	MTOR	51件: EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, HIF-1 ...	D00753	Sirolimus	40件: 2, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, ...
5	MTOR	51件: EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, HIF-1 ...	D02714	Everolimus	9件: 34, 67, 89, 96, 137, 157, 158, 228, 277
6	MTOR	51件: EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, HIF-1 ...	D06068	Temsirolimus	1件: 13
7	MSTN	1件: Cytokine-cytokine receptor interaction	D05917	Stamulumab	1件: 113
8	MSTN	1件: Cytokine-cytokine receptor interaction	D11047	Domagrozumab	1件: 113
9	MSTN	1件: Cytokine-cytokine receptor interaction	D11265	Talditercept alfa	1件: 3
10	MSTN	1件: Cytokine-cytokine receptor interaction	D11797	Apitegromab	1件: 3

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