Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Abiraterone
(Synonym: Abiraterone Accord)		[3] Abiraterone; Abiraterone acetate; ZYTIGA---[2] 75, 81
2 Acetaminophen
(Synonym: Childrens ACCUDIAL Pain reliever/ Fever reducer)		[4] Acetaminophen; PARACETAMOL; Tylenol; Ultracet[1] D00217 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[15] 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337
3 Acetylsalicylic acid
(Synonym: Healthy Accents migraine formula)		[2] ACETYLSALICYLIC ACID; Aspirin[1] D00109 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251
4 Alendronic acid
(Synonym: Accel-alendronate)		[3] Alendronate; Alendronate sodium; Alendronic acid[1] D07119 [1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[7] 19, 41, 46, 50, 271, 274, 299
5 Aluminum hydroxide
(Synonym: Healthy Accents Maldroxal)		[2] Aluminium hydroxide; Aluminum hydroxide[1] D02416 --[2] 11, 46
6 Amlodipine
(Synonym: Accel-amlodipine)		[1] AMLODIPINE[1] D07450 [4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 13, 51, 67, 298
7 Anastrozole
(Synonym: Accel-anastrozole Tablets)		[2] Anastrozole; Arimidex[1] D00960 [1] CYP19A1 💬[3] Metabolic pathways, Ovarian steroidogenesis, Steroid hormone biosynthesis 💬[3] 78, 86, 193
8 Apixaban
(Synonym: Apixaban Accord)		[2] Apixaban; Eliquis[1] D03213 [1] F10 💬[1] Complement and coagulation cascades 💬[1] 222
9 Aripiprazole
(Synonym: Aripiprazole Accord)		[1] Aripiprazole[1] D01164 [4] DRD2,
DRD3,
HTR1A,
HTR2A 💬		[12] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬[2] 6, 206
10 Bortezomib
(Synonym: Bortezomib Accord)		[3] BORTEZOMIB; Bortezomib Accord; Velcade[1] D03150 [1] PSMB5 💬[8] Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Proteasome, Spinocerebellar ataxia 💬[17] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331
11 Bosentan
(Synonym: Accel-bosentan)		[2] BOSENTAN; TRACLEER[2] D01227 ,
D07538 		[2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212
12 Caffeine
(Synonym: Healthy Accents migraine formula)		[1] Caffeine[2] D00528 ,
D01453 		[11] ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬		[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[8] 2, 6, 21, 46, 78, 96, 97, 265
13 Calcium carbonate
(Synonym: Healthy Accents Famotidine Calcium Carbonate Magnesium Hydroxide)		[3] Calcio carbonato; Calcium; Calcium carbonate[2] D00932 ,
D10802 		--[9] 13, 19, 46, 53, 75, 96, 235, 274, 299
14 Candesartan cilexetil
(Synonym: Accel-candesartan)		[1] CANDESARTAN[1] D00626 [1] AGTR1 💬[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 67
15 Caspofungin
(Synonym: Caspofungin Accord)		[2] Caspofungin; CASPOFUNGIN ACETATE[1] D07626 --[1] 60
16 Celecoxib
(Synonym: Accel-celecoxib)		[2] CELEBREX; CELECOXIB[1] D00567 [1] PTGS2 💬[22] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[10] 2, 3, 34, 46, 70, 89, 107, 161, 171, 271
17 Cetirizine
(Synonym: Healthy Accents Cetirizine Hydrochloride)		[3] Cetirizina; Cetirizine; CETIRIZINE HYDROCHLORIDE[1] D07662 [1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[4] 13, 28, 35, 300
18 Chlorpheniramine
(Synonym: Healthy Accents Multi Symptom Cold)		[1] Clorfenamina[1] D07398 [1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[1] 14
19 Chromium
(Synonym: Accelerator)		[1] Chromium---[1] 46
20 Cinacalcet
(Synonym: Cinacalcet Accordpharma)		[1] Cinacalcet[1] D03504 [1] CASR 💬[2] NOD-like receptor signaling pathway, Parathyroid hormone synthesis, secretion and action 💬[1] 238
21 Citalopram
(Synonym: Accel-citalopram Tablets)		[1] Citalopram[1] D07704 [1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[7] 6, 8, 13, 18, 46, 98, 127
22 Clonazepam
(Synonym: Accel-clonazepam)		[1] Clonazepam[1] D00280 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[1] 6
23 Clopidogrel
(Synonym: Accel-clopidogrel)		[1] Clopidogrel[3] D07729 ,
D10823 ,
D10824 		[1] P2RY12 💬[1] Platelet activation 💬[3] 49, 51, 86
24 Clotrimazole
(Synonym: Healthy Accents Antifungal)		[1] Clotrimazole[1] D00282 --[1] 97
25 Dalfampridine
(Synonym: Fampridine Accord)		[7] 4-Aminopyridine; 4-AP; Ampyra; Dalfampridine; FAMPRIDINA; FAMPRIDINE; Fampyra[1] D04127 [4] KCNA4,
KCNC3,
KCND2,
KCND3 💬		[4] Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬[5] 3, 4, 6, 13, 14
26 Dasatinib
(Synonym: Dasatinib Accordpharma)		[1] Dasatinib[2] D03658 ,
D06414 		[8] ABL1,
EPHA2,
FYN,
KIT,
LCK,
PDGFRB,
SRC,
YES1 💬		[77] Acute myeloid leukemia, Adherens junction, Axon guidance, Bacterial invasion of epithelial cells, Bladder cancer, Breast cancer, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, GABAergic synapse, Gap junction, Glioma, GnRH signaling pathway, Hematopoietic cell lineage, Hepatitis B, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Inflammatory mediator regulation of TRP channels, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Mitophagy - animal, NF-kappa B signaling pathway, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Platelet activation, Primary immunodeficiency, Prion disease, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Sphingolipid signaling pathway, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Thyroid hormone signaling pathway, Tight junction, Tuberculosis, VEGF signaling pathway, Viral carcinogenesis, Viral myocarditis, Yersinia infection 💬[2] 51, 85
27 Deferasirox
(Synonym: Deferasirox Accord)		[2] DEFERASIROX; EXJADE[1] D03669 --[3] 254, 284, 286
28 Dexamethasone
(Synonym: Accufix II Dec Model 033-212)		[5] Decadron; Dexametasona; Dexamethasone; DEXAMETHASONE SODIUM PHOSPHATE; Maxidex[1] D00292 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[22] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 81, 84, 96, 97, 162, 222, 235, 257, 283, 296, 299
29 Dexmedetomidine
(Synonym: Dexmedetomidine Accord)		[4] Dexdor; DEXMEDETOMIDINA; Dexmedetomidine; DEXMEDETOMIDINE HYDROCHLORIDE[1] D00514 [3] ADRA2A,
ADRA2B,
ADRA2C 💬		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[14] 2, 4, 6, 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280
30 Dextromethorphan
(Synonym: Healthy Accents Cough and Sore Throat Night Time)		[4] Dextromethorphan; Dextromethorphan hydrobromide; Dextrometorfano; Nuedexta[1] D03742 [6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
31 Diphenhydramine
(Synonym: Healthy Accents Ibuprofen PM)		[2] Diphenhydramine; Diphenhydramine hydrochloride[1] D00300 [1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[8] 11, 13, 49, 51, 70, 86, 222, 256
32 Donepezil
(Synonym: Accel-donepezil)		[3] Aricept; Donepezil; Donepezil hydrochloride[1] D07869 [1] ACHE 💬[2] Cholinergic synapse, Glycerophospholipid metabolism 💬[9] 5, 6, 13, 46, 78, 124, 127, 156, 206
33 Duloxetine
(Synonym: Accel-duloxetine)		[3] CYMBALTA; Duloxetine; Duloxetine hydrochloride[1] D07880 [2] SLC6A2,
SLC6A4 💬		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[2] 6, 13
34 Efavirenz
(Synonym: Atripla Access)		[2] Efavirenz; SUSTIVA[1] D00896 --[1] 265
35 Emtricitabine
(Synonym: Truvada Access)		[2] Emtricitabine; TRUVADA[1] D01199 --[4] 25, 93, 265, 325
36 Entecavir
(Synonym: Accel-entecavir)		[1] Entecavir[2] D04008 ,
D07896 		--[6] 46, 56, 96, 97, 107, 271
37 Esomeprazole
(Synonym: Healthy Accents Esomeprazole Magnesium)		[3] Esomeprazole; Nexium; Omeprazole[1] D07917 [2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[8] 13, 46, 86, 98, 107, 113, 298, 299
38 Ethanol
(Synonym: Accessory Workshop Instant Hand Sanitizer)		[3] Alcohol; Ethanol; PREDNISONE[1] D06542 --[5] 58, 97, 279, 280, 298
39 Famotidine
(Synonym: Healthy Accents Famotidine Calcium Carbonate Magnesium Hydroxide)		[2] FAMOTIDINA; Famotidine[1] D00318 [1] HRH2 💬[3] Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬[6] 6, 46, 61, 86, 98, 107
40 Ferric maltol
(Synonym: Accrufer)		[1] Ferric Maltol[1] D10833 (Name: Accrufer (TN))--[1] 96
41 Fexofenadine
(Synonym: Healthy Accents Allergy Relief)		[1] Fexofenadine[1] D07958 [1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[2] 13, 46
42 Filgrastim
(Synonym: Accofil)		[7] Filgrastim; Filgrastim Hexal; G-CSF; Granulocyte Colony Stimulating Factor; Neupogen; TEVAGRASTIM; Zarzio[1] D03235 [1] CSF3R 💬[5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[35] 2, 6, 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331
43 Finasteride
(Synonym: Accel-finasteride Tablets USP)		[1] Finasteride[1] D00321 [1] SRD5A2 💬[3] Metabolic pathways, Prostate cancer, Steroid hormone biosynthesis 💬[1] 6
44 Fingolimod
(Synonym: Fingolimod Accord)		[3] FINGOLIMOD; FINGOLIMOD HYDROCHLORIDE; GILENYA[1] D10001 [1] S1PR1 💬[3] FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬[3] 13, 14, 156
45 Fluoxetine
(Synonym: Accel-fluoxetine)		[5] Fluoxetin; Fluoxetine; FLUOXETINE HYDROCHLORIDE; Fluoxétine; PROZAC[1] D00326 [1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[6] 13, 17, 78, 86, 179, 206
46 Fluticasone propionate
(Synonym: Healthy Accents Nasoflow)		[3] Flovent; Fluticasone; FLUTICASONE PROPIONATE[1] D01708 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[2] 98, 228
47 Hydrochlorothiazide
(Synonym: Accel-candesartan/hctz)		[2] Esidrix; HYDROCHLOROTHIAZIDE[1] D00340 [1] SLC12A3 💬-[4] 13, 67, 225, 235
48 Hydrocortisone
(Synonym: Healthy Accents Cortisone Maximum Strength)		[6] Cortef; Cortisol; Cortisone; Hydrocortisone; Hydrocortisone cream; Hydrocortisonum[1] D00088 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[10] 6, 41, 46, 53, 75, 78, 81, 83, 97, 299
49 Ibandronate
(Synonym: Ibandronic Acid Accord)		[2] Ibandronate; Ibandronic acid---[3] 46, 49, 274
50 Ibuprofen
(Synonym: Healthy Accents ibuprofen childrens)		[2] Ibuprofen; IBUPROFEN 200MG[1] D00126 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[7] 13, 46, 65, 107, 113, 271, 299
51 Imatinib
(Synonym: Imatinib Accord)		[4] Gleevec; GLIVEC; Imatinib; Imatinib Mesylate[1] D08066 [3] ABL1,
KIT,
PDGFRA 💬		[32] Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Choline metabolism in cancer, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis 💬[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
52 Isotretinoin
(Synonym: Accutane Roche)		[1] Isotretinoin[1] D00348 (Name: Accutane (TN))[2] RARA,
RARB 💬		[8] Acute myeloid leukemia, Estrogen signaling pathway, Gastric cancer, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer 💬[4] 36, 39, 159, 160
53 Lacosamide
(Synonym: Lacosamide Accord)		[1] Lacosamide[1] D07299 [2] SCN3A,
SCN9A 💬		[1] Taste transduction 💬[4] 2, 46, 149, 298
54 Lansoprazole
(Synonym: Healthy Accents Lansoprazole)		[1] Lansoprazole[1] D00355 [2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[7] 63, 71, 85, 98, 166, 222, 299
55 Ledipasvir
(Synonym: Harvoni Access)		[1] Ledipasvir[1] D10442 --[1] 19
56 Leflunomide
(Synonym: Accel-leflunomide)		[3] ARAVA; LEFLUNOMIDE; Leflunomidum[1] D00749 [1] DHODH 💬[3] Biosynthesis of cofactors, Metabolic pathways, Pyrimidine metabolism 💬[12] 11, 40, 46, 49, 53, 66, 107, 162, 224, 270, 271, 300
57 Lenalidomide
(Synonym: Lenalidomide Accord)		[2] Lenalidomide; REVLIMID[1] D04687 [1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[8] 16, 26, 28, 34, 49, 284, 300, 331
58 Letrozole
(Synonym: Accel-letrozole Tablets USP)		[1] Letrozole[1] D00964 [1] CYP19A1 💬[3] Metabolic pathways, Ovarian steroidogenesis, Steroid hormone biosynthesis 💬[2] 81, 89
59 Levetiracetam
(Synonym: Levetiracetam Accord)		[2] KEPPRA; Levetiracetam[1] D00709 [1] SV2A 💬[1] ECM-receptor interaction 💬[5] 2, 4, 6, 13, 307
60 Lidocaine
(Synonym: Accucaine)		[4] Aloe; Lidocaine; Lignocaine; Xylocaine[2] D00358 ,
D08127 		[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256
61 Loperamide
(Synonym: Healthy Accents Anti Diarrheal)		[2] Loperamide; Loperamide hydrochloride[1] D08144 [3] OPRD1,
OPRK1,
OPRM1 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[2] 13, 97
62 Loratadine
(Synonym: Healthy Accents Allergy and Congestion Relief 24 Hour Non Drowsy)		[2] Loratadina; Loratadine[1] D00364 [1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[4] 13, 46, 89, 98
63 Magnesium hydroxide
(Synonym: Healthy Accents Antacid)		[1] Magnesium hydroxide[1] D00731 --[1] 284
64 Memantine
(Synonym: Memantine Accord)		[3] EBIXA; Memantine; MEMANTINE HYDROCHLORIDE[1] D08174 [5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[8] 2, 6, 8, 13, 49, 127, 205, 206
65 Metformin
(Synonym: Vildagliptin/metformin Hydrochloride Accord)		[5] Metformin; Metformin HCl; Metformin Hydrochloride; Metformina; Metformine[1] D04966 [2] PRKAA1,
PRKAA2 💬		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[25] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301
66 Mineral oil
(Synonym: Healthy Accents Hemorrhoidal)		[1] Paraffin Oil[1] D05042 --[1] 291
67 Montelukast
(Synonym: Accel-montelukast Sodium Tablets)		[3] Montelukast; MONTELUKAST SODIUM; Singulair[1] D08229 [1] CYSLTR1 💬[2] Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬[8] 6, 13, 46, 61, 63, 85, 98, 228
68 Mycophenolate mofetil
(Synonym: Accel-mycophenolate Mofetil Capsules)		[3] CellCept; Mycophenolate mofetil; Mycophenolate mofetil TEVA[1] D00752 [2] IMPDH1,
IMPDH2 💬		[4] Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬[34] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300
69 Naproxen
(Synonym: Healthy Accents All Day Pain Relief)		[5] Naprosyn; Naproxen; Naproxen oral suspension; NAPROXEN SODIUM; Propanoic acid[1] D00118 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[4] 13, 46, 107, 271
70 Neomycin
(Synonym: Healthy Accents Triple Antibiotic)		[1] Neomycin[1] D08260 --[3] 96, 97, 296
71 Nicotine
(Synonym: Healthy Accents Nicotine)		[2] Nicotine; Nicotine gum[1] D03365 [16] CHRNA1,
CHRNA10,
CHRNA2,
CHRNA3,
CHRNA4,
CHRNA5,
CHRNA6,
CHRNA7,
CHRNA9,
CHRNB1,
CHRNB2,
CHRNB3,
CHRNB4,
CHRND,
CHRNE,
CHRNG 💬		[8] Alzheimer disease, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Virion - Lyssavirus 💬[3] 6, 13, 84
72 Olanzapine
(Synonym: Accel-olanzapine)		[2] OLANZAPINE; Zyprexa[1] D00454 [11] ADRA1A,
ADRA1B,
ADRA1D,
DRD2,
DRD3,
DRD4,
HRH1,
HTR2A,
HTR2B,
HTR2C,
HTR6 💬		[16] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Salivary secretion, Serotonergic synapse, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 2, 8
73 Omeprazole
(Synonym: Healthy Accents Omeprazole)		[4] Losec; Omeprazol; Omeprazole; OMEPRAZOLE MAGNESIUM[1] D00455 [2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[14] 6, 8, 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299
74 Ondansetron
(Synonym: Accel-ondansetron)		[1] Ondansetron[1] D00456 [5] HTR3A,
HTR3B,
HTR3C,
HTR3D,
HTR3E 💬		[2] Serotonergic synapse, Taste transduction 💬[3] 6, 97, 107
75 Petrolatum
(Synonym: Healthy Accents Hemorrhoidal)		[1] Petrolatum[1] D05331 --[1] 158
76 Phenylephrine
(Synonym: AccuHist)		[1] Phenylephrine[1] D08365 [3] ADRA1A,
ADRA1B,
ADRA1D 💬		[7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 22
77 Pioglitazone
(Synonym: Pioglitazone Accord)		[1] Pioglitazone[1] D08378 [1] PPARG 💬[11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299
78 Polyethylene glycol
(Synonym: Healthy Accents Clear Lax)		[4] Macrogol; Macrogol 4000; Polyethylene glycol; Polyethylene Glycol 3350[1] D03370 --[17] 6, 13, 41, 46, 60, 65, 78, 96, 97, 140, 144, 235, 240, 246, 276, 299, 337
79 Posaconazole
(Synonym: Posaconazole Accord)		[2] Noxafil; POSACONAZOLE[1] D02555 --[3] 60, 65, 299
80 Pramipexole
(Synonym: Pramipexole Accord)		[7] Mirapex; Mirapex ER; Mirapexin; Pramipexol; Pramipexole; PRAMIPEXOLE DIHYDROCHLORIDE; SIFROL[1] D05575 [3] DRD2,
DRD3,
DRD4 💬		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 2, 6, 20
81 Pregabalin
(Synonym: Pregabalin Accord)		[2] Lyrica; Pregabalin[1] D02716 [4] CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4 💬		[7] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway 💬[5] 13, 36, 46, 70, 298
82 Pseudoephedrine
(Synonym: Healthy Accents Nasal Decongestant)		[1] Pseudoephedrine[1] D08449 [9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		[14] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 17
83 Quetiapine
(Synonym: Accel-quetiapine)		[2] Quetiapine; Seroquel[1] D08456 [2] DRD2,
HTR2A 💬		[11] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬[2] 6, 13
84 Quinapril
(Synonym: Accupril Tab 20mg)		[1] Accuretic[1] D03752 [1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[1] 19
85 Ranitidine
(Synonym: Healthy Accents Ranitidine)		[1] Ranitidine[1] D00422 [1] HRH2 💬[3] Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬[2] 13, 65
86 Repaglinide
(Synonym: Repaglinide Accord)		[1] Repaglinide[1] D00594 [2] ABCC8,
KCNJ11 💬		[4] ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬[4] 6, 21, 46, 299
87 Rilpivirine
(Synonym: COMPLERA Access)		[1] Rilpivirine[1] D09720 --[1] 256
88 Rivaroxaban
(Synonym: Rivaroxaban Accord)		[2] RIVAROXABAN; Xarelto[1] D07086 [1] F10 💬[1] Complement and coagulation cascades 💬[4] 46, 49, 91, 210
89 Salbutamol
(Synonym: AccuNeb)		[3] Albuterol; Salbutamol; Ventolin[1] D02147 [1] ADRB2 💬[9] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[12] 3, 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299
90 Sevelamer
(Synonym: Accel-sevelamer)		[1] Sevelamer[1] D08512 --[2] 235, 238
91 Sildenafil
(Synonym: Accel-sildenafil)		[6] Mysildecard; Revatio; SILDENAFIL; Sildenafil Citrate; SILDENAFILO; Viagra[1] D08514 [1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[17] 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301
92 Sodium fluoride
(Synonym: Colgate Trilple Accion)		[1] Sodium fluoride[1] D00943 --[1] 51
93 Sofosbuvir
(Synonym: Sovaldi Access)		[1] Sofosbuvir[1] D10366 --[1] 19
94 Sunitinib
(Synonym: Sunitinib Accord)		[2] Sunitinib; Sunitinib malate[1] D08552 [9] CSF1R,
FLT1,
FLT3,
FLT4,
KDR,
KIT,
PDGFRA,
PDGFRB,
RET 💬		[36] Acute myeloid leukemia, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Endocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, Gap junction, Glioma, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Thyroid cancer, Transcriptional misregulation in cancer, VEGF signaling pathway, Viral protein interaction with cytokine and cytokine receptor 💬[2] 28, 34
95 Temozolomide
(Synonym: Emozolomide Accord)		[1] Temozolomide[1] D06067 --[1] 34
96 Tenofovir disoproxil
(Synonym: Truvada Access)		[4] Tenofovir; Tenofovir disoproxil; Tenofovir Disoproxil Fumarate; TRUVADA---[2] 93, 265
97 Teriflunomide
(Synonym: Teriflunomide Accord)		[2] AUBAGIO; Teriflunomide[1] D10172 [1] DHODH 💬[3] Biosynthesis of cofactors, Metabolic pathways, Pyrimidine metabolism 💬[3] 13, 25, 26
98 Theophylline [1] Theophylline[2] D00371 ,
D06103 (Name: Accurbron (TN))		[18] ADORA1,
ADORA2B,
PDE10A,
PDE11A,
PDE1A,
PDE1B,
PDE1C,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE7A,
PDE7B,
PDE8A,
PDE8B 💬		[23] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 236, 299
99 Tigecycline
(Synonym: Tigecycline Accord)		[1] Tigecycline[1] D01079 --[1] 93
100 Topiramate
(Synonym: Accel-topiramate)		[2] TOPAMAX; Topiramate[1] D00537 [36] CA2,
CA4,
CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S,
GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ,
GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[53] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Arrhythmogenic right ventricular cardiomyopathy, Bile secretion, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Collecting duct acid secretion, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Huntington disease, Hypertrophic cardiomyopathy, Insulin secretion, Long-term depression, Long-term potentiation, MAPK signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Nitrogen metabolism, Oxytocin signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Prion disease, Proximal tubule bicarbonate reclamation, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Tight junction, Transcriptional misregulation in cancer, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[6] 6, 97, 140, 144, 156, 193
101 Triamcinolone
(Synonym: Healthy Accents Nasal Allergy)		[4] Kenalog; Naltrexone; Triamcinolone; Triamcinolone Acetonide[1] D00385 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[11] 35, 46, 53, 56, 70, 90, 96, 107, 162, 226, 298
102 Voriconazole
(Synonym: Voriconazole Accord)		[2] Vfend; VORICONAZOLE[1] D00578 --[2] 60, 299
103 Zinc acetate
(Synonym: Healthy Accents Anti Itch)		[2] Wilzin; Zinc acetate[1] D06408 --[2] 171, 299
104 Zinc oxide
(Synonym: ESIKA TRIPLE ACCION MAX BB Light Beige)		[1] Zinc oxide[1] D01170 --[1] 156
105 Zoledronic acid
(Synonym: Zoledronic Acid Accord)		[4] ACLASTA; Zoledronate; ZOLEDRONIC ACID; Zometa[2] D01968 ,
D08689 		[1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[13] 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333