Target Gene/Pathway Pathway / Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Lipid and atherosclerosis 💬	[1] BCL2 💬	D10679 💬	Venetoclax	[1] 28 💬
2	Lipid and atherosclerosis 💬	[1] CASP9 💬	D11195 💬	Rimiducid	[6] 19, 60, 65, 284, 285, 326 💬
3	Lipid and atherosclerosis 💬	[4] CCL2, IL1B, IL6, TNF 💬	D01583 💬	Pirfenidone	[11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
4	Lipid and atherosclerosis 💬	[1] CD40 💬	D11357 💬	Bleselumab	[1] 222 💬
5	Lipid and atherosclerosis 💬	[1] CD40 💬	D11610 💬	Iscalimab	[2] 49, 53 💬
6	Lipid and atherosclerosis 💬	[1] CD40 💬	D11597 💬	Ravagalimab	[2] 53, 97 💬
7	Lipid and atherosclerosis 💬	[1] CD40LG 💬	D06193 💬	Toralizumab	[1] 63 💬
8	Lipid and atherosclerosis 💬	[13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 ...	D09662 💬	Rontalizumab	[1] 49 💬
9	Lipid and atherosclerosis 💬	[13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 ...	D09668 💬	Sifalimumab	[1] 49 💬
10	Lipid and atherosclerosis 💬	[2] IL12A, IL12B 💬	D09214 💬	Ustekinumab	[16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬

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