Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Human T-cell leukemia virus 1 infection 💬
 [3] CD3D, CD3E, CD3G 💬 D08959 💬 Otelixizumab [1] 46 💬
2 Human T-cell leukemia virus 1 infection 💬
 [3] CD3D, CD3E, CD3G 💬 D06314 💬 Visilizumab [2] 96, 97 💬
3 Human T-cell leukemia virus 1 infection 💬
 [1] CD3E 💬 D11463 💬 Mosunetuzumab [1] 49 💬
4 Human T-cell leukemia virus 1 infection 💬
 [1] CD4 💬 D06356 💬 Zanolimumab [1] 46 💬
5 Human T-cell leukemia virus 1 infection 💬
 [1] CD40 💬 D11357 💬 Bleselumab [1] 222 💬
6 Human T-cell leukemia virus 1 infection 💬
 [1] CD40 💬 D11610 💬 Iscalimab [2] 49, 53 💬
7 Human T-cell leukemia virus 1 infection 💬
 [1] CD40 💬 D11597 💬 Ravagalimab [2] 53, 97 💬
8 Human T-cell leukemia virus 1 infection 💬
 [1] CDK4 💬 D10688 💬 Abemaciclib [1] 34 💬
9 Human T-cell leukemia virus 1 infection 💬
 [1] CSF2 💬 D11343 💬 Otilimab [1] 46 💬
10 Human T-cell leukemia virus 1 infection 💬
 [1] FDPS 💬 D07119 💬 Alendronic acid [7] 19, 41, 46, 50, 271, 274, 299 💬
11 Human T-cell leukemia virus 1 infection 💬
 [1] FDPS 💬 D07281 💬 Pamidronic acid [3] 270, 271, 274 💬
12 Human T-cell leukemia virus 1 infection 💬
 [1] FDPS 💬 D08484 💬 Risedronic acid [9] 46, 50, 66, 93, 95, 96, 107, 113, 274 💬
13 Human T-cell leukemia virus 1 infection 💬
 [1] FDPS 💬 D01968 💬 Zoledronic acid [13]  5 ,  6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬
14 Human T-cell leukemia virus 1 infection 💬
 [1] FDPS 💬 D08689 💬 Zoledronic acid [13]  5 ,  6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬
15 Human T-cell leukemia virus 1 infection 💬
 [2] IL1R1, IL1R2 💬 D02934 💬 Anakinra [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
16 Human T-cell leukemia virus 1 infection 💬
 [1] IL2RA 💬 D03058 💬 Basiliximab [6]  2 , 50, 66, 97, 222, 228 💬
17 Human T-cell leukemia virus 1 infection 💬
 [1] IL2RA 💬 D03639 💬 Daclizumab [8] 13, 56, 60, 65, 97, 107, 283, 284 💬
18 Human T-cell leukemia virus 1 infection 💬
 [3] IL2RA, IL2RB, IL2RG 💬 D00748 💬 Aldesleukin [6]  2 , 35, 49, 65, 96, 97 💬
19 Human T-cell leukemia virus 1 infection 💬
 [1] IL6 💬 D12487 💬 Olokizumab [2] 46, 96 💬
20 Human T-cell leukemia virus 1 infection 💬
 [1] IL6 💬 D09669 💬 Siltuximab [2] 28, 331 💬
21 Human T-cell leukemia virus 1 infection 💬
 [1] IL6 💬 D10080 💬 Sirukumab [2] 41, 46 💬
22 Human T-cell leukemia virus 1 infection 💬
 [2] IL6, TNF 💬 D01583 💬 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
23 Human T-cell leukemia virus 1 infection 💬
 [2] IL6, TNF 💬 D08976 💬 Pomalidomide [5] 28, 51, 85, 227, 331 💬
24 Human T-cell leukemia virus 1 infection 💬
 [1] ITGAL 💬 D03959 💬 Efalizumab [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
25 Human T-cell leukemia virus 1 infection 💬
 [1] JAK1 💬 D11400 💬 Abrocitinib [1] 84 💬
26 Human T-cell leukemia virus 1 infection 💬
 [1] JAK1 💬 D10308 💬 Baricitinib [13]  2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
27 Human T-cell leukemia virus 1 infection 💬
 [1] JAK1 💬 D10871 💬 Filgotinib [6] 46, 53, 96, 97, 222, 271 💬
28 Human T-cell leukemia virus 1 infection 💬
 [1] JAK1 💬 D10944 💬 Itacitinib [4] 46, 51, 97, 228 💬
29 Human T-cell leukemia virus 1 infection 💬
 [1] JAK1 💬 D09959 💬 Ruxolitinib [3] 60, 65, 228 💬
30 Human T-cell leukemia virus 1 infection 💬
 [1] JAK1 💬 D10994 💬 Upadacitinib [8] 40, 41, 46, 49, 96, 97, 107, 271 💬
31 Human T-cell leukemia virus 1 infection 💬
 [2] JAK1, JAK3 💬 D10653 💬 Peficitinib [1] 46 💬
32 Human T-cell leukemia virus 1 infection 💬
 [2] JAK1, JAK3 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
33 Human T-cell leukemia virus 1 infection 💬
 [1] LCK 💬 D03658 💬 Dasatinib [2] 51, 85 💬
34 Human T-cell leukemia virus 1 infection 💬
 [1] LCK 💬 D06414 💬 Dasatinib [2] 51, 85 💬
35 Human T-cell leukemia virus 1 infection 💬
 [1] LTA 💬 D10187 💬 Pateclizumab [1] 46 💬
36 Human T-cell leukemia virus 1 infection 💬
 [2] LTA, TNF 💬 D00742 💬 Etanercept [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
37 Human T-cell leukemia virus 1 infection 💬
 [2] MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib [1] 34 💬
38 Human T-cell leukemia virus 1 infection 💬
 [2] MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib [1] 280 💬
39 Human T-cell leukemia virus 1 infection 💬
 [2] MAP2K1, MAP2K2 💬 D11675 💬 Mirdametinib [1] 34 💬
40 Human T-cell leukemia virus 1 infection 💬
 [2] MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib [1] 34 💬
41 Human T-cell leukemia virus 1 infection 💬
 [2] MAP2K1, MAP2K2 💬 D10175 💬 Trametinib [4]  2 , 34, 279, 280 💬
42 Human T-cell leukemia virus 1 infection 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [5] 46, 51, 53, 271, 300 💬
43 Human T-cell leukemia virus 1 infection 💬
 [1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
44 Human T-cell leukemia virus 1 infection 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
45 Human T-cell leukemia virus 1 infection 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
46 Human T-cell leukemia virus 1 infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
47 Human T-cell leukemia virus 1 infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D05480 💬 Pimecrolimus [1] 160 💬
48 Human T-cell leukemia virus 1 infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
49 Human T-cell leukemia virus 1 infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
50 Human T-cell leukemia virus 1 infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D09033 💬 Voclosporin [2] 49, 222 💬
51 Human T-cell leukemia virus 1 infection 💬
 [1] RELA 💬 D12181 💬 Edasalonexent [1] 113 💬
52 Human T-cell leukemia virus 1 infection 💬
 [3] TGFB1, TGFB2, TGFB3 💬 D09620 💬 Fresolimumab [3] 51, 85, 222 💬
53 Human T-cell leukemia virus 1 infection 💬
 [1] TNF 💬 D02597 💬 Adalimumab [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
54 Human T-cell leukemia virus 1 infection 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
55 Human T-cell leukemia virus 1 infection 💬
 [1] TNF 💬 D04358 💬 Golimumab [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
56 Human T-cell leukemia virus 1 infection 💬
 [1] TNF 💬 D02598 💬 Infliximab [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
57 Human T-cell leukemia virus 1 infection 💬
 [1] TNF 💬 D04687 💬 Lenalidomide [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
58 Human T-cell leukemia virus 1 infection 💬
 [1] TNF 💬 D09944 💬 Ozoralizumab [1] 46 💬
59 Human T-cell leukemia virus 1 infection 💬
 [1] TNF 💬 D05393 💬 Pegsunercept [1] 46 💬
60 Human T-cell leukemia virus 1 infection 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
61 Human T-cell leukemia virus 1 infection 💬
 [1] TNFRSF13C 💬 D12151 💬 Ianalumab [7] 35, 46, 49, 53, 61, 63, 95 💬
62 Human T-cell leukemia virus 1 infection 💬
 [1] XPO1 💬 D11222 💬 Selinexor [1] 28 💬