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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1ABC008----1件: 15
2ADSVF----2件: 15, 96
3ALEMTUZUMAB1件: Alemtuzumab1件: D02802 1件: CD52 💬-17件: 13, 15, 19, 20, 36, 43, 44, 46, 51, 60, 63, 65, 85, 96, 164, 283, 284
4Alemtuzumab (Campath)1件: Alemtuzumab1件: D02802 1件: CD52 💬-1件: 15
5Anakinra1件: Anakinra1件: D02934 2件: IL1R1,
IL1R2 💬		15件: Amoebiasis, Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, MAPK signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Pathogenic Escherichia coli infection, Prostate cancer, Shigellosis, Th17 cell differentiation, Transcriptional misregulation in cancer 💬17件: 2, 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 84, 86, 97, 106, 107, 299
6ARIMOCLOMOL1件: Arimoclomol1件: D11374 --3件: 2, 15, 19
7Arimoclomol citrate1件: Arimoclomol1件: D11374 --2件: 15, 19
8Bimagrumab1件: Bimagrumab1件: D10620 2件: ACVR2A,
ACVR2B 💬		4件: Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Signaling pathways regulating pluripotency of stem cells, TGF-beta signaling pathway 💬1件: 15
9BOTULINUM TOXIN TYPE A1件: Botulinum toxin type A1件: D00783 1件: SNAP25 💬2件: Insulin secretion, Synaptic vesicle cycle 💬10件: 2, 5, 6, 7, 13, 15, 17, 70, 113, 149
10BRX-345----2件: 2, 15
11BYM338----1件: 15
12BYM338 (Bimagrumab)1件: Bimagrumab1件: D10620 2件: ACVR2A,
ACVR2B 💬		4件: Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Signaling pathways regulating pluripotency of stem cells, TGF-beta signaling pathway 💬1件: 15
13BYM338/bimagrumab1件: Bimagrumab1件: D10620 2件: ACVR2A,
ACVR2B 💬		4件: Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Signaling pathways regulating pluripotency of stem cells, TGF-beta signaling pathway 💬1件: 15
14Calcium1件: Calcium---30件: 3, 6, 13, 15, 19, 46, 49, 51, 53, 56, 68, 75, 79, 84, 93, 94, 95, 96, 97, 186, 214, 215, 222, 224, 235, 256, 265, 274, 298, 299
15Care as usual----1件: 15
16Creatine1件: Creatine---16件: 1, 2, 3, 5, 6, 8, 13, 15, 21, 46, 49, 50, 113, 156, 201, 256
17Diagnostic Test: Beck depression inventory fast screen (Questionnaire)----3件: 3, 15, 256
18Diagnostic Test: Borg Scale----3件: 3, 15, 256
19Diagnostic Test: Brief Pain Inventory (BPI) (Questionnaire)----3件: 3, 15, 256
20Diagnostic Test: Fatigue Severity and Disability Scale (FSS) (Questionnaire)----3件: 3, 15, 256
21Diagnostic Test: German Pain Inventory (Questionnaire)----3件: 3, 15, 256
22Diagnostic Test: Handheld Dynamometry (HHD)----3件: 3, 15, 256
23Diagnostic Test: Laboratory assessment: calcium1件: Calcium---3件: 3, 15, 256
24Diagnostic Test: Laboratory assessment: Creatine kinase1件: Creatine---3件: 3, 15, 256
25Diagnostic Test: Laboratory assessment: magnesium1件: Magnesium---3件: 3, 15, 256
26Diagnostic Test: Laboratory assessment: phosphate1件: Phosphate ion---3件: 3, 15, 256
27Diagnostic Test: Laboratory assessment: Vitamin D Level1件: Vitamin D---3件: 3, 15, 256
28Diagnostic Test: Muscle ultrasound----3件: 3, 15, 256
29Diagnostic Test: Pressure pain threshold----4件: 3, 15, 113, 256
30Diagnostic Test: Quick Motor Function Test----4件: 3, 15, 113, 256
31Diagnostic Test: R-PAct (Questionnaire)----3件: 3, 15, 256
32Diagnostic Test: Rotterdam Handicap Scale (RHS) (Questionnaire)----3件: 3, 15, 256
33Diagnostic Test: Six-minute walk test (6MWT)----3件: 3, 15, 256
34Diagnostic Test: Vital signs----3件: 3, 15, 256
35Etanercept1件: Etanercept1件: D00742 2件: LTA,
TNF 💬		67件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬16件: 15, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298
36FLEBOGAMMA 5%----1件: 15
37Gamma Globulin----2件: 15, 50
38Genetic: Blood draw for optional genetic exome sequencing----3件: 3, 15, 256
39Genetic: Genetic test: ACE polymorphism----3件: 3, 15, 256
40Genetic: Genetic test: ACTN3 polymorphism----3件: 3, 15, 256
41Immunoglobulins, normal human, for intravascular adm.----2件: 14, 15
42Magnesium1件: Magnesium---19件: 3, 6, 11, 13, 15, 46, 64, 70, 93, 97, 166, 225, 235, 256, 284, 291, 296, 297, 298
43NATALIZUMAB1件: Natalizumab1件: D06886 1件: ITGA4 💬14件: Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Human papillomavirus infection, Hypertrophic cardiomyopathy, Intestinal immune network for IgA production, Leishmaniasis, Leukocyte transendothelial migration, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Yersinia infection 💬5件: 13, 15, 25, 46, 96
44Null----16件: 6, 13, 15, 28, 37, 46, 49, 51, 63, 86, 90, 96, 97, 107, 145, 271
45Other: Blood-flow restricted training----1件: 15
46PHENYLBUTYRATE1件: Phenylbutyric acid---12件: 2, 3, 6, 8, 15, 93, 94, 244, 251, 297, 299, 338
47Phenylbutyrate Oral Tablet1件: Phenylbutyric acid---1件: 15
48Phosphate1件: Phosphate ion---33件: 2, 3, 6, 11, 12, 13, 15, 28, 36, 46, 49, 51, 53, 60, 62, 65, 70, 78, 81, 83, 90, 96, 97, 164, 235, 238, 256, 276, 283, 284, 285, 286, 299
49Pioglitazone1件: Pioglitazone2件: D00945 ,
D08378 		1件: PPARG 💬11件: AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299
50RAAV1.CMV.huFollistatin344----2件: 15, 113
51Rapamycin1件: Sirolimus1件: D00753 1件: MTOR 💬51件: AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬19件: 2, 15, 34, 35, 46, 49, 51, 60, 61, 67, 86, 89, 96, 157, 158, 193, 256, 278, 279
52REGN2477+REGN1033----1件: 15
53Simvastatin1件: Simvastatin1件: D00434 1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬21件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310
54Sirolimus1件: Sirolimus1件: D00753 1件: MTOR 💬51件: AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬36件: 6, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 89, 98, 127, 137, 157, 158, 192, 222, 277, 278, 279, 280, 281, 283, 285, 331
55SIVASTIN----1件: 15
56Vitamin D1件: Vitamin D---24件: 3, 13, 15, 19, 41, 43, 44, 46, 49, 50, 68, 93, 95, 96, 97, 98, 179, 222, 228, 235, 256, 274, 298, 299
57Xeomin1件: Botulinum toxin type A1件: D00783 1件: SNAP25 💬2件: Insulin secretion, Synaptic vesicle cycle 💬7件: 5, 6, 7, 13, 15, 17, 113