Target Gene/Pathway Pathway / Gene
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Showing 1 to 10 of 32 entries
| No. | KEGG GENES | KEGG PATHWAY | KEGG DRUG | DrugBank | 指定難病告示番号 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| 1 |
ABL1
💬1. ABL1
| 11件: ErbB signaling pathway ErbB signaling pathway, Ras signaling pathway, Cell cycle, Axon guidance, Neurotrophin signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, MicroRNAs in cancer, Chemical carcinogenesis - reactive oxygen species, Chronic myeloid leukemia, Viral myocarditis 11件: ErbB signaling pathway, Ras signaling pathway, Cell cycle, Axon guidance, Neurotrophin signalin ... | Imatinib
Imatinib
💬1. ABL1
| Imatinib | 12件: 13 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬1. ABL1
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| 2 |
CSF3R
💬2. CSF3R
| 5件: Cytokine-cytokine receptor interaction Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Hematopoietic cell lineage, Pathways in cancer 5件: Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, ... | Filgrastim
Filgrastim
💬2. CSF3R
| Filgrastim | 35件: 2 2, 6, 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬 35件: 2, 6, 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 6 ... 2. CSF3R
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| 3 |
DHFR
💬3. DHFR
| 5件: One carbon pool by folate One carbon pool by folate, Folate biosynthesis, Metabolic pathways, Biosynthesis of cofactors, Antifolate resistance 5件: One carbon pool by folate, Folate biosynthesis, Metabolic pathways, Biosynthesis of cofactors, A ... | Methotrexate
Methotrexate
💬3. DHFR
| Methotrexate | 38件: 11 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, ... 3. DHFR
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| 4 |
DHFR2
💬4. DHFR2
| 5件: One carbon pool by folate One carbon pool by folate, Folate biosynthesis, Metabolic pathways, Biosynthesis of cofactors, Antifolate resistance 5件: One carbon pool by folate, Folate biosynthesis, Metabolic pathways, Biosynthesis of cofactors, A ... | Methotrexate
Methotrexate
💬4. DHFR2
| Methotrexate | 38件: 11 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, ... 4. DHFR2
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| 5 |
FCGRT
💬5. FCGRT
| - | Efgartigimod alfa
Efgartigimod alfa
💬5. FCGRT
| Efgartigimod alfa | 6件: 11 11, 14, 35, 53, 63, 162 💬
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| 6 |
HRH1
💬6. HRH1
| 3件: Calcium signaling pathway Calcium signaling pathway, Neuroactive ligand-receptor interaction, Inflammatory mediator regulation of TRP channels 3件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Inflammatory mediator regula ... | Cetirizine
Cetirizine
💬6. HRH1
| Cetirizine | 4件: 13 13, 28, 35, 300 💬
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| 7 |
IL2RA
💬7. IL2RA
| 11件: Cytokine-cytokine receptor interaction Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, Endocytosis, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Hematopoietic cell lineage, Th1 and Th2 cell differentiation, Th17 cell differentiation, Measles, Human T-cell leukemia virus 1 infection, Pathways in cancer 11件: Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine re ... | Aldesleukin
Aldesleukin
💬7. IL2RA
| Aldesleukin | 6件: 2 2, 35, 49, 65, 96, 97 💬
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| 8 |
IL2RB
💬8. IL2RB
| 11件: Cytokine-cytokine receptor interaction Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, Endocytosis, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Measles, Human T-cell leukemia virus 1 infection, Pathways in cancer, Transcriptional misregulation in cancer 11件: Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine re ... | Aldesleukin
Aldesleukin
💬8. IL2RB
| Aldesleukin | 6件: 2 2, 35, 49, 65, 96, 97 💬
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| 9 |
IL2RG
💬9. IL2RG
| 12件: Cytokine-cytokine receptor interaction Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, Endocytosis, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Measles, Human T-cell leukemia virus 1 infection, Pathways in cancer, Inflammatory bowel disease, Primary immunodeficiency 12件: Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine re ... | Aldesleukin
Aldesleukin
💬9. IL2RG
| Aldesleukin | 6件: 2 2, 35, 49, 65, 96, 97 💬
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| 10 |
IMPDH1
💬10. IMPDH1
| 4件: Purine metabolism Purine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism | Mycophenolate mofetil
Mycophenolate mofetil
💬10. IMPDH1
| Mycophenolate mofetil | 34件: 2 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 34件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, ... 10. IMPDH1
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