DDrare
Disease
Drug
Target Gene/Pathway
問合せ先
EN
Target Gene/Pathway
Pathway
/
Gene
Search
A
B
C
D
E
F
G
H
I
J
K
L
M
N
O
P
Q
R
S
T
U
V
W
X
Y
Z
Other
Search results
10
50
100
ALL
entries per page:
Showing 1 to 10 of 70 entries
Filter by
Reset
|
No.
KEGG GENES
KEGG PATHWAY
KEGG DRUG
DrugBank
指定難病告示番号
1
TNFSF13B
💬
1. TNFSF13B
×
Name
Full Name
TNFSF13B
TNF superfamily member 13b
4件:
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
NF-kappa B signaling pathway
,
Intestinal immune network for IgA production
,
Rheumatoid arthritis
4件:
Cytokine-cytokine receptor interaction
,
NF-kappa B signaling pathway
,
Intestinal immune network
...
Belimumab
Belimumab
💬
1. TNFSF13B
×
Name
Other Names
Belimumab
Belimumab (USAN)
Belimumab (genetical recombination) (JAN)
Benlysta (TN)
LymphoStat-B (TN)
ベリムマブ
ベンリスタ
Belimumab
13件:
11
11
,
13
,
43
,
44
,
46
,
49
,
51
,
53
,
63
,
66
,
222
,
296
,
300
💬
1. TNFSF13B
×
告示番号
日本語名
英語名
11
重症筋無力症
Myasthenia gravis
13
多発性硬化症/視神経脊髄炎
Multiple sclerosis/Neuromyelitis optica
43
顕微鏡的多発血管炎
Microscopic polyangiitis
44
多発血管炎性肉芽腫症;ウェゲナー肉芽腫症
Wegener granulomatosis
46
悪性関節リウマチ
Malignant rheumatoid arthritis
49
全身性エリテマトーデス
Systemic lupus erythematosus
51
全身性強皮症
Scleroderma
53
シェーグレン症候群
Sjogren syndrome
63
特発性血小板減少性紫斑病;一次性免疫性血小板減少症
Idiopathic thrombocytopenic purpura
66
IgA腎症
IgA nephropathy
222
一次性ネフローゼ症候群
Primary nephrotic syndrome
296
胆道閉鎖症
Biliary atresia
300
IgG4関連疾患
IgG4-related disease
2
TNFSF13B
💬
2. TNFSF13B
×
Name
Full Name
TNFSF13B
TNF superfamily member 13b
4件:
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
NF-kappa B signaling pathway
,
Intestinal immune network for IgA production
,
Rheumatoid arthritis
4件:
Cytokine-cytokine receptor interaction
,
NF-kappa B signaling pathway
,
Intestinal immune network
...
Atacicept
Atacicept
💬
2. TNFSF13B
×
Name
Other Names
Atacicept
Atacicept (USAN/INN)
アタシセプト
Atacicept
4件:
13
13
,
46
,
49
,
66
💬
2. TNFSF13B
×
告示番号
日本語名
英語名
13
多発性硬化症/視神経脊髄炎
Multiple sclerosis/Neuromyelitis optica
46
悪性関節リウマチ
Malignant rheumatoid arthritis
49
全身性エリテマトーデス
Systemic lupus erythematosus
66
IgA腎症
IgA nephropathy
3
TNFSF13B
💬
3. TNFSF13B
×
Name
Full Name
TNFSF13B
TNF superfamily member 13b
4件:
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
NF-kappa B signaling pathway
,
Intestinal immune network for IgA production
,
Rheumatoid arthritis
4件:
Cytokine-cytokine receptor interaction
,
NF-kappa B signaling pathway
,
Intestinal immune network
...
Tabalumab
Tabalumab
💬
3. TNFSF13B
×
Name
Other Names
Tabalumab
Tabalumab (USAN)
Tabalumab (genetical recombination) (JAN)
タバルマブ
Tabalumab
2件:
46
46
,
49
💬
3. TNFSF13B
×
告示番号
日本語名
英語名
46
悪性関節リウマチ
Malignant rheumatoid arthritis
49
全身性エリテマトーデス
Systemic lupus erythematosus
4
TNFSF13B
💬
4. TNFSF13B
×
Name
Full Name
TNFSF13B
TNF superfamily member 13b
4件:
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
NF-kappa B signaling pathway
,
Intestinal immune network for IgA production
,
Rheumatoid arthritis
4件:
Cytokine-cytokine receptor interaction
,
NF-kappa B signaling pathway
,
Intestinal immune network
...
Tibulizumab
Tibulizumab
💬
4. TNFSF13B
×
Name
Other Names
Tibulizumab
Tibulizumab (USAN/INN)
チブリズマブ
Tibulizumab
1件:
53
53
💬
4. TNFSF13B
×
告示番号
日本語名
英語名
53
シェーグレン症候群
Sjogren syndrome
5
TNFRSF13C
💬
5. TNFRSF13C
×
Name
Full Name
TNFRSF13C
TNF receptor superfamily member 13C
5件:
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
NF-kappa B signaling pathway
,
Intestinal immune network for IgA production
,
Human T-cell leukemia virus 1 infection
,
Primary immunodeficiency
5件:
Cytokine-cytokine receptor interaction
,
NF-kappa B signaling pathway
,
Intestinal immune network
...
Ianalumab
Ianalumab
💬
5. TNFRSF13C
×
Name
Other Names
Ianalumab
Ianalumab (USAN/INN)
アイアナルマブ
イアナルマブ
Ianalumab
7件:
35
35
,
46
,
49
,
53
,
61
,
63
,
95
💬
5. TNFRSF13C
×
告示番号
日本語名
英語名
35
天疱瘡
Pemphigus
46
悪性関節リウマチ
Malignant rheumatoid arthritis
49
全身性エリテマトーデス
Systemic lupus erythematosus
53
シェーグレン症候群
Sjogren syndrome
61
自己免疫性溶血性貧血
Autoimmune hemolytic anemia
63
特発性血小板減少性紫斑病;一次性免疫性血小板減少症
Idiopathic thrombocytopenic purpura
95
自己免疫性肝炎
Autoimmune hepatitis
6
PARP1
💬
6. PARP1
×
Name
Full Name
PARP1
poly(ADP-ribose) polymerase 1
5件:
Base excision repair
Base excision repair
,
NF-kappa B signaling pathway
,
Apoptosis
,
Necroptosis
,
Diabetic cardiomyopathy
5件:
Base excision repair
,
NF-kappa B signaling pathway
,
Apoptosis
,
Necroptosis
,
Diabetic cardiomyopa
...
Olaparib
Olaparib
💬
6. PARP1
×
Name
Other Names
Olaparib
Olaparib (JAN/USAN/INN)
Lynparza (TN)
オラパリブ
リムパーザ
Olaparib
2件:
86
86
,
285
💬
6. PARP1
×
告示番号
日本語名
英語名
86
肺動脈性肺高血圧症
Pulmonary arterial hypertension
285
ファンコニ貧血
Fanconi anemia
7
IL1B
💬
7. IL1B
×
Name
Full Name
IL1B
interleukin 1 beta
44件:
Antifolate resistance
Antifolate resistance
,
MAPK signaling pathway
,
Cytokine-cytokine receptor interaction
,
NF-kappa B signaling pathway
,
Necroptosis
,
Osteoclast differentiation
,
Toll-like receptor signaling pathway
,
NOD-like receptor signaling pathway
,
Cytosolic DNA-sensing pathway
,
C-type lectin receptor signaling pathway
,
Hematopoietic cell lineage
,
IL-17 signaling pathway
,
Th17 cell differentiation
,
TNF signaling pathway
,
Inflammatory mediator regulation of TRP channels
,
Non-alcoholic fatty liver disease
,
AGE-RAGE signaling pathway in diabetic complications
,
Alcoholic liver disease
,
Type I diabetes mellitus
,
Alzheimer disease
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Pathogenic Escherichia coli infection
,
Shigellosis
,
Salmonella infection
,
Pertussis
,
Legionellosis
,
Yersinia infection
,
Leishmaniasis
,
Chagas disease
,
African trypanosomiasis
,
Malaria
,
Amoebiasis
,
Tuberculosis
,
Measles
,
Human cytomegalovirus infection
,
Influenza A
,
Herpes simplex virus 1 infection
,
Coronavirus disease - COVID-19
,
Inflammatory bowel disease
,
Rheumatoid arthritis
,
Graft-versus-host disease
,
Lipid and atherosclerosis
,
Fluid shear stress and atherosclerosis
44件:
Antifolate resistance
,
MAPK signaling pathway
,
Cytokine-cytokine receptor interaction
,
NF-kappa
...
Pirfenidone
Pirfenidone
💬
7. IL1B
×
Name
Other Names
Pirfenidone
Pirfenidone (JAN/USAN/INN)
Esbriet (TN)
ピルフェニドン
ピレスパ
Pirfenidone
11件:
13
13
,
34
,
46
,
50
,
51
,
58
,
84
,
85
,
164
,
222
,
228
💬
7. IL1B
×
告示番号
日本語名
英語名
13
多発性硬化症/視神経脊髄炎
Multiple sclerosis/Neuromyelitis optica
34
神経線維腫症
Neurofibromatosis
46
悪性関節リウマチ
Malignant rheumatoid arthritis
50
皮膚筋炎/多発性筋炎
Dermatomyositis
51
全身性強皮症
Scleroderma
58
肥大型心筋症
Hypertrophic cardiomyopathy
84
サルコイドーシス
Sarcoidosis
85
特発性間質性肺炎
Idiopathic interstitial pneumonia
164
眼皮膚白皮症
Oculocutaneous albinism
222
一次性ネフローゼ症候群
Primary nephrotic syndrome
228
閉塞性細気管支炎
Bronchiolitis obliterans
8
IL1B
💬
8. IL1B
×
Name
Full Name
IL1B
interleukin 1 beta
44件:
Antifolate resistance
Antifolate resistance
,
MAPK signaling pathway
,
Cytokine-cytokine receptor interaction
,
NF-kappa B signaling pathway
,
Necroptosis
,
Osteoclast differentiation
,
Toll-like receptor signaling pathway
,
NOD-like receptor signaling pathway
,
Cytosolic DNA-sensing pathway
,
C-type lectin receptor signaling pathway
,
Hematopoietic cell lineage
,
IL-17 signaling pathway
,
Th17 cell differentiation
,
TNF signaling pathway
,
Inflammatory mediator regulation of TRP channels
,
Non-alcoholic fatty liver disease
,
AGE-RAGE signaling pathway in diabetic complications
,
Alcoholic liver disease
,
Type I diabetes mellitus
,
Alzheimer disease
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Pathogenic Escherichia coli infection
,
Shigellosis
,
Salmonella infection
,
Pertussis
,
Legionellosis
,
Yersinia infection
,
Leishmaniasis
,
Chagas disease
,
African trypanosomiasis
,
Malaria
,
Amoebiasis
,
Tuberculosis
,
Measles
,
Human cytomegalovirus infection
,
Influenza A
,
Herpes simplex virus 1 infection
,
Coronavirus disease - COVID-19
,
Inflammatory bowel disease
,
Rheumatoid arthritis
,
Graft-versus-host disease
,
Lipid and atherosclerosis
,
Fluid shear stress and atherosclerosis
44件:
Antifolate resistance
,
MAPK signaling pathway
,
Cytokine-cytokine receptor interaction
,
NF-kappa
...
Rilonacept
Rilonacept
💬
8. IL1B
×
Name
Other Names
Rilonacept
Rilonacept (USAN/INN)
Arcalyst (TN)
リロナセプト
Rilonacept
4件:
51
51
,
106
,
107
,
266
💬
8. IL1B
×
告示番号
日本語名
英語名
51
全身性強皮症
Scleroderma
106
クリオピリン関連周期熱症候群
Cryopyrin-associated periodic syndrome
107
若年性特発性関節炎
Juvenile idiopathic arthritis
266
家族性地中海熱
Familial mediterranean fever
9
IL1B
💬
9. IL1B
×
Name
Full Name
IL1B
interleukin 1 beta
44件:
Antifolate resistance
Antifolate resistance
,
MAPK signaling pathway
,
Cytokine-cytokine receptor interaction
,
NF-kappa B signaling pathway
,
Necroptosis
,
Osteoclast differentiation
,
Toll-like receptor signaling pathway
,
NOD-like receptor signaling pathway
,
Cytosolic DNA-sensing pathway
,
C-type lectin receptor signaling pathway
,
Hematopoietic cell lineage
,
IL-17 signaling pathway
,
Th17 cell differentiation
,
TNF signaling pathway
,
Inflammatory mediator regulation of TRP channels
,
Non-alcoholic fatty liver disease
,
AGE-RAGE signaling pathway in diabetic complications
,
Alcoholic liver disease
,
Type I diabetes mellitus
,
Alzheimer disease
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Pathogenic Escherichia coli infection
,
Shigellosis
,
Salmonella infection
,
Pertussis
,
Legionellosis
,
Yersinia infection
,
Leishmaniasis
,
Chagas disease
,
African trypanosomiasis
,
Malaria
,
Amoebiasis
,
Tuberculosis
,
Measles
,
Human cytomegalovirus infection
,
Influenza A
,
Herpes simplex virus 1 infection
,
Coronavirus disease - COVID-19
,
Inflammatory bowel disease
,
Rheumatoid arthritis
,
Graft-versus-host disease
,
Lipid and atherosclerosis
,
Fluid shear stress and atherosclerosis
44件:
Antifolate resistance
,
MAPK signaling pathway
,
Cytokine-cytokine receptor interaction
,
NF-kappa
...
Canakinumab
Canakinumab
💬
9. IL1B
×
Name
Other Names
Canakinumab
Canakinumab (USAN/INN)
Canakinumab (genetical recombination) (JAN)
Ilaris (TN)
カナキヌマブ
イラリス
Canakinumab
10件:
46
46
,
56
,
84
,
106
,
107
,
108
,
113
,
266
,
267
,
269
💬
9. IL1B
×
告示番号
日本語名
英語名
46
悪性関節リウマチ
Malignant rheumatoid arthritis
56
ベーチェット病
Behcet disease
84
サルコイドーシス
Sarcoidosis
106
クリオピリン関連周期熱症候群
Cryopyrin-associated periodic syndrome
107
若年性特発性関節炎
Juvenile idiopathic arthritis
108
TNF受容体関連周期性症候群
TNF receptor-associated periodic syndrome
113
筋ジストロフィー
Muscular dystrophy
266
家族性地中海熱
Familial mediterranean fever
267
高IgD症候群
Hyper-IgD syndrome
269
化膿性無菌性関節炎・壊疽性膿皮症・アクネ症候群;PAPA症候群
Pyogenic arthritis
10
IL1B
💬
10. IL1B
×
Name
Full Name
IL1B
interleukin 1 beta
44件:
Antifolate resistance
Antifolate resistance
,
MAPK signaling pathway
,
Cytokine-cytokine receptor interaction
,
NF-kappa B signaling pathway
,
Necroptosis
,
Osteoclast differentiation
,
Toll-like receptor signaling pathway
,
NOD-like receptor signaling pathway
,
Cytosolic DNA-sensing pathway
,
C-type lectin receptor signaling pathway
,
Hematopoietic cell lineage
,
IL-17 signaling pathway
,
Th17 cell differentiation
,
TNF signaling pathway
,
Inflammatory mediator regulation of TRP channels
,
Non-alcoholic fatty liver disease
,
AGE-RAGE signaling pathway in diabetic complications
,
Alcoholic liver disease
,
Type I diabetes mellitus
,
Alzheimer disease
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Pathogenic Escherichia coli infection
,
Shigellosis
,
Salmonella infection
,
Pertussis
,
Legionellosis
,
Yersinia infection
,
Leishmaniasis
,
Chagas disease
,
African trypanosomiasis
,
Malaria
,
Amoebiasis
,
Tuberculosis
,
Measles
,
Human cytomegalovirus infection
,
Influenza A
,
Herpes simplex virus 1 infection
,
Coronavirus disease - COVID-19
,
Inflammatory bowel disease
,
Rheumatoid arthritis
,
Graft-versus-host disease
,
Lipid and atherosclerosis
,
Fluid shear stress and atherosclerosis
44件:
Antifolate resistance
,
MAPK signaling pathway
,
Cytokine-cytokine receptor interaction
,
NF-kappa
...
Gevokizumab
Gevokizumab
💬
10. IL1B
×
Name
Other Names
Gevokizumab
Gevokizumab (USAN/INN)
ゲボキズマブ
Gevokizumab
4件:
41
41
,
50
,
56
,
269
💬
10. IL1B
×
告示番号
日本語名
英語名
41
巨細胞性動脈炎;側頭動脈炎
Giant cell arteritis
50
皮膚筋炎/多発性筋炎
Dermatomyositis
56
ベーチェット病
Behcet disease
269
化膿性無菌性関節炎・壊疽性膿皮症・アクネ症候群;PAPA症候群
Pyogenic arthritis