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KEGG GENES
KEGG PATHWAY
KEGG DRUG
DrugBank
指定難病告示番号
1
CNR1
💬
1. CNR1
×
Name
Full Name
CNR1
cannabinoid receptor 1
4件:
Rap1 signaling pathway
Rap1 signaling pathway
,
Neuroactive ligand-receptor interaction
,
Thermogenesis
,
Retrograde endocannabinoid signaling
4件:
Rap1 signaling pathway
,
Neuroactive ligand-receptor interaction
,
Thermogenesis
,
Retrograde endoc
...
Dronabinol
Dronabinol
💬
1. CNR1
×
Name
Other Names
Dronabinol
Dronabinol (USP/INN)
Tetrahydrocannabinol
Marinol (TN)
SYNDROS
ドロナビノール
テトラヒドロカンナビノール
Dronabinol
8件:
2
2
,
8
,
13
,
36
,
46
,
96
,
271
,
298
💬
1. CNR1
×
告示番号
日本語名
英語名
2
筋萎縮性側索硬化症
Amyotrophic lateral sclerosis
8
ハンチントン病
Huntington disease
13
多発性硬化症／視神経脊髄炎
Multiple sclerosis/Neuromyelitis optica
36
表皮水疱症
Epidermolysis bullosa
46
悪性関節リウマチ
Malignant rheumatoid arthritis
96
クローン病;回腸末端炎
Crohn disease
271
強直性脊椎炎
Ankylosing spondylitis
298
遺伝性膵炎
Hereditary pancreatitis
2
CNR1
💬
2. CNR1
×
Name
Full Name
CNR1
cannabinoid receptor 1
4件:
Rap1 signaling pathway
Rap1 signaling pathway
,
Neuroactive ligand-receptor interaction
,
Thermogenesis
,
Retrograde endocannabinoid signaling
4件:
Rap1 signaling pathway
,
Neuroactive ligand-receptor interaction
,
Thermogenesis
,
Retrograde endoc
...
Nabilone
Nabilone
💬
2. CNR1
×
Name
Other Names
Nabilone
Nabilone (USAN/INN)
Cesamet (TN)
ナビロン
Nabilone
3件:
6
6
,
13
,
127
💬
2. CNR1
×
告示番号
日本語名
英語名
6
パーキンソン病
Parkinson disease
13
多発性硬化症／視神経脊髄炎
Multiple sclerosis/Neuromyelitis optica
127
前頭側頭葉変性症
Frontotemporal lobar degeneration
3
CNR1
💬
3. CNR1
×
Name
Full Name
CNR1
cannabinoid receptor 1
4件:
Rap1 signaling pathway
Rap1 signaling pathway
,
Neuroactive ligand-receptor interaction
,
Thermogenesis
,
Retrograde endocannabinoid signaling
4件:
Rap1 signaling pathway
,
Neuroactive ligand-receptor interaction
,
Thermogenesis
,
Retrograde endoc
...
Rimonabant
Rimonabant
💬
3. CNR1
×
Name
Other Names
Rimonabant
Rimonabant (JAN/USAN/INN)
Acomplia (TN)
リモナバント
リモナバン
Rimonabant
1件:
193
193
💬
3. CNR1
×
告示番号
日本語名
英語名
193
プラダー・ウィリ症候群
Prader-Willi syndrome
4
CNR1
💬
4. CNR1
×
Name
Full Name
CNR1
cannabinoid receptor 1
4件:
Rap1 signaling pathway
Rap1 signaling pathway
,
Neuroactive ligand-receptor interaction
,
Thermogenesis
,
Retrograde endocannabinoid signaling
4件:
Rap1 signaling pathway
,
Neuroactive ligand-receptor interaction
,
Thermogenesis
,
Retrograde endoc
...
Cannabidiol
Cannabidiol
💬
4. CNR1
×
Name
Other Names
Cannabidiol
Cannabidiol (USAN/INN)
Epidiolex (TN)
カンナビジオール
Cannabidiol
20件:
2
2
,
6
,
8
,
13
,
36
,
46
,
51
,
95
,
96
,
97
,
140
,
144
,
145
,
156
,
157
,
158
,
193
,
206
,
226
,
271
💬
4. CNR1
×
告示番号
日本語名
英語名
2
筋萎縮性側索硬化症
Amyotrophic lateral sclerosis
6
パーキンソン病
Parkinson disease
8
ハンチントン病
Huntington disease
13
多発性硬化症／視神経脊髄炎
Multiple sclerosis/Neuromyelitis optica
36
表皮水疱症
Epidermolysis bullosa
46
悪性関節リウマチ
Malignant rheumatoid arthritis
51
全身性強皮症
Scleroderma
95
自己免疫性肝炎
Autoimmune hepatitis
96
クローン病;回腸末端炎
Crohn disease
97
潰瘍性大腸炎
Ulcerative colitis
140
ドラベ症候群
Dorabe syndrome
144
レノックス・ガストー症候群
Lennox-Gastaut syndrome
145
ウエスト症候群
West syndrome
156
レット症候群
Rett syndrome
157
スタージ・ウェーバー症候群
Sturge-Weber syndrome
158
結節性硬化症
Tuberous sclerosis
193
プラダー・ウィリ症候群
Prader-Willi syndrome
206
脆弱Ｘ症候群
Fragile X syndrome
226
間質性膀胱炎（ハンナ型）
Interstitial cystitis with Hunners ulcer
271
強直性脊椎炎
Ankylosing spondylitis
5
MAPK14
💬
5. MAPK14
×
Name
Full Name
MAPK14
mitogen-activated protein kinase 14
62件:
Endocrine resistance
Endocrine resistance
,
MAPK signaling pathway
,
Rap1 signaling pathway
,
FoxO signaling pathway
,
Sphingolipid signaling pathway
,
Oocyte meiosis
,
Cellular senescence
,
Adrenergic signaling in cardiomyocytes
,
VEGF signaling pathway
,
Osteoclast differentiation
,
Signaling pathways regulating pluripotency of stem cells
,
Platelet activation
,
Neutrophil extracellular trap formation
,
Toll-like receptor signaling pathway
,
NOD-like receptor signaling pathway
,
RIG-I-like receptor signaling pathway
,
C-type lectin receptor signaling pathway
,
IL-17 signaling pathway
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
T cell receptor signaling pathway
,
Fc epsilon RI signaling pathway
,
TNF signaling pathway
,
Leukocyte transendothelial migration
,
Thermogenesis
,
Neurotrophin signaling pathway
,
Retrograde endocannabinoid signaling
,
Dopaminergic synapse
,
Inflammatory mediator regulation of TRP channels
,
GnRH signaling pathway
,
Progesterone-mediated oocyte maturation
,
Prolactin signaling pathway
,
Relaxin signaling pathway
,
Non-alcoholic fatty liver disease
,
AGE-RAGE signaling pathway in diabetic complications
,
Growth hormone synthesis, secretion and action
,
Alcoholic liver disease
,
Amyotrophic lateral sclerosis
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Epithelial cell signaling in Helicobacter pylori infection
,
Pathogenic Escherichia coli infection
,
Shigellosis
,
Salmonella infection
,
Pertussis
,
Yersinia infection
,
Leishmaniasis
,
Chagas disease
,
Toxoplasmosis
,
Tuberculosis
,
Hepatitis B
,
Human cytomegalovirus infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Epstein-Barr virus infection
,
Human immunodeficiency virus 1 infection
,
Coronavirus disease - COVID-19
,
Proteoglycans in cancer
,
Chemical carcinogenesis - reactive oxygen species
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
Diabetic cardiomyopathy
,
Lipid and atherosclerosis
,
Fluid shear stress and atherosclerosis
62件:
Endocrine resistance
,
MAPK signaling pathway
,
Rap1 signaling pathway
,
FoxO signaling pathway
,
S
...
Losmapimod
Losmapimod
💬
5. MAPK14
×
Name
Other Names
Losmapimod
Losmapimod (USAN/INN)
ロスマピモド
Losmapimod
2件:
113
113
,
222
💬
5. MAPK14
×
告示番号
日本語名
英語名
113
筋ジストロフィー
Muscular dystrophy
222
一次性ネフローゼ症候群
Primary nephrotic syndrome
6
MAPK14
💬
6. MAPK14
×
Name
Full Name
MAPK14
mitogen-activated protein kinase 14
62件:
Endocrine resistance
Endocrine resistance
,
MAPK signaling pathway
,
Rap1 signaling pathway
,
FoxO signaling pathway
,
Sphingolipid signaling pathway
,
Oocyte meiosis
,
Cellular senescence
,
Adrenergic signaling in cardiomyocytes
,
VEGF signaling pathway
,
Osteoclast differentiation
,
Signaling pathways regulating pluripotency of stem cells
,
Platelet activation
,
Neutrophil extracellular trap formation
,
Toll-like receptor signaling pathway
,
NOD-like receptor signaling pathway
,
RIG-I-like receptor signaling pathway
,
C-type lectin receptor signaling pathway
,
IL-17 signaling pathway
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
T cell receptor signaling pathway
,
Fc epsilon RI signaling pathway
,
TNF signaling pathway
,
Leukocyte transendothelial migration
,
Thermogenesis
,
Neurotrophin signaling pathway
,
Retrograde endocannabinoid signaling
,
Dopaminergic synapse
,
Inflammatory mediator regulation of TRP channels
,
GnRH signaling pathway
,
Progesterone-mediated oocyte maturation
,
Prolactin signaling pathway
,
Relaxin signaling pathway
,
Non-alcoholic fatty liver disease
,
AGE-RAGE signaling pathway in diabetic complications
,
Growth hormone synthesis, secretion and action
,
Alcoholic liver disease
,
Amyotrophic lateral sclerosis
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Epithelial cell signaling in Helicobacter pylori infection
,
Pathogenic Escherichia coli infection
,
Shigellosis
,
Salmonella infection
,
Pertussis
,
Yersinia infection
,
Leishmaniasis
,
Chagas disease
,
Toxoplasmosis
,
Tuberculosis
,
Hepatitis B
,
Human cytomegalovirus infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Epstein-Barr virus infection
,
Human immunodeficiency virus 1 infection
,
Coronavirus disease - COVID-19
,
Proteoglycans in cancer
,
Chemical carcinogenesis - reactive oxygen species
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
Diabetic cardiomyopathy
,
Lipid and atherosclerosis
,
Fluid shear stress and atherosclerosis
62件:
Endocrine resistance
,
MAPK signaling pathway
,
Rap1 signaling pathway
,
FoxO signaling pathway
,
S
...
Neflamapimod
Neflamapimod
💬
6. MAPK14
×
Name
Other Names
Neflamapimod
Neflamapimod (USAN)
ネフラマピモド
Neflamapimod
1件:
8
8
💬
6. MAPK14
×
告示番号
日本語名
英語名
8
ハンチントン病
Huntington disease
7
GABRA1
💬
7. GABRA1
×
Name
Full Name
GABRA1
gamma-aminobutyric acid type A receptor subunit alpha1
6件:
Neuroactive ligand-receptor interaction
Neuroactive ligand-receptor interaction
,
Retrograde endocannabinoid signaling
,
GABAergic synapse
,
Taste transduction
,
Morphine addiction
,
Nicotine addiction
6件:
Neuroactive ligand-receptor interaction
,
Retrograde endocannabinoid signaling
,
GABAergic synapse
...
Alprazolam
Alprazolam
💬
7. GABRA1
×
Name
Other Names
Alprazolam
Alprazolam (JP18/USP/INN)
Xanax (TN)
ALPRAZOLAM C-IV
アルプラゾラム
コンスタン
ソラナックス
Alprazolam
2件:
8
8
,
75
💬
7. GABRA1
×
告示番号
日本語名
英語名
8
ハンチントン病
Huntington disease
75
クッシング病
Cushing disease
8
GABRA1
💬
8. GABRA1
×
Name
Full Name
GABRA1
gamma-aminobutyric acid type A receptor subunit alpha1
6件:
Neuroactive ligand-receptor interaction
Neuroactive ligand-receptor interaction
,
Retrograde endocannabinoid signaling
,
GABAergic synapse
,
Taste transduction
,
Morphine addiction
,
Nicotine addiction
6件:
Neuroactive ligand-receptor interaction
,
Retrograde endocannabinoid signaling
,
GABAergic synapse
...
Clonazepam
Clonazepam
💬
8. GABRA1
×
Name
Other Names
Clonazepam
Clonazepam (JP18/USP/INN)
Klonopin (TN)
クロナゼパム
ランドセン
リボトリール
Clonazepam
1件:
6
6
💬
8. GABRA1
×
告示番号
日本語名
英語名
6
パーキンソン病
Parkinson disease
9
GABRA1
💬
9. GABRA1
×
Name
Full Name
GABRA1
gamma-aminobutyric acid type A receptor subunit alpha1
6件:
Neuroactive ligand-receptor interaction
Neuroactive ligand-receptor interaction
,
Retrograde endocannabinoid signaling
,
GABAergic synapse
,
Taste transduction
,
Morphine addiction
,
Nicotine addiction
6件:
Neuroactive ligand-receptor interaction
,
Retrograde endocannabinoid signaling
,
GABAergic synapse
...
Diazepam
Diazepam
💬
9. GABRA1
×
Name
Other Names
Diazepam
Diazepam (JP18/USP/INN)
Diastat (TN)
Valium (TN)
VALTOCO
DIAZEPAM INTENSOL
ジアゼパム
セルシン
ダイアップ
ホリゾン
Diazepam
3件:
46
46
,
155
,
298
💬
9. GABRA1
×
告示番号
日本語名
英語名
46
悪性関節リウマチ
Malignant rheumatoid arthritis
155
ランドウ・クレフナー症候群
Acquired aphasia with convulsive disorder
298
遺伝性膵炎
Hereditary pancreatitis
10
GABRA1
💬
10. GABRA1
×
Name
Full Name
GABRA1
gamma-aminobutyric acid type A receptor subunit alpha1
6件:
Neuroactive ligand-receptor interaction
Neuroactive ligand-receptor interaction
,
Retrograde endocannabinoid signaling
,
GABAergic synapse
,
Taste transduction
,
Morphine addiction
,
Nicotine addiction
6件:
Neuroactive ligand-receptor interaction
,
Retrograde endocannabinoid signaling
,
GABAergic synapse
...
Lorazepam
Lorazepam
💬
10. GABRA1
×
Name
Other Names
Lorazepam
Lorazepam (JP18/USP/INN)
Ativan (TN)
LOREEV XR
ロラゼパム
ロラピタ
ワイパックス
Lorazepam
1件:
36
36
💬
10. GABRA1
×
告示番号
日本語名
英語名
36
表皮水疱症
Epidermolysis bullosa