Target Gene/Pathway Pathway / Gene

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No.

KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related

1

Insulin signaling pathway 💬

[1] BRAF 💬

Dabrafenib 💬

[1] 34 💬

2

Insulin signaling pathway 💬

[2] BRAF, RAF1 💬

[2] 34, 86 💬

3

Insulin signaling pathway 💬

[1] INSR 💬

Insulin detemir 💬

Insulin detemir

[1] 299 💬

4

Insulin signaling pathway 💬

[1] INSR 💬

Insulin glargine 💬

Name	Other Names
Insulin glargine	Insulin glargine (USAN/INN) Insulin glargine (genetical recombination) (JP18) Insulin glargine (genetical recombination) [Insulin glargin biosimilar 1] (JAN) Insulin glargine (genetical recombination) [Insulin glargin biosimilar 2] (JAN) Lantus (TN) BASAGLAR INSULIN GLARGINE SOLOSTAR LANTUS SOLOSTAR REZVOGLAR SEMGLEE TOUJEO TOUJEO MAX

Insulin glargine

[1] 299 💬

5

Insulin signaling pathway 💬

[1] INSR 💬

Insulin human 💬

[2] 96, 156 💬

6

Insulin signaling pathway 💬

[2] MAP2K1, MAP2K2 💬

Binimetinib 💬

[1] 34 💬

7

Insulin signaling pathway 💬

[2] MAP2K1, MAP2K2 💬

Cobimetinib 💬

[1] 280 💬

8

Insulin signaling pathway 💬

[2] MAP2K1, MAP2K2 💬

Mirdametinib 💬

[1] 34 💬

9

Insulin signaling pathway 💬

[2] MAP2K1, MAP2K2 💬

Selumetinib 💬

[1] 34 💬

10

Insulin signaling pathway 💬

[2] MAP2K1, MAP2K2 💬

Trametinib 💬

[4] 2 , 34, 279, 280 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
34	Neurofibromatosis;
279	Huge venous malformation with cervical, oral and pharyngeal diffuse lesion;Huge venous malformation;Venous malformation;
280	Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;

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