Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
---|---|---|---|---|---|
1 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
BRAF [1] BRAF 💬 |
Dabrafenib Dabrafenib 💬 |
Dabrafenib | 034 [1] 34 💬 💬 |
2 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
BRAF [3] BRAF, PDGFRB, RAF1 💬 |
Sorafenib Sorafenib 💬 |
Sorafenib | 034 [2] 34, 86 💬 💬 |
3 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
C5 [1] C5 💬 |
Crovalimab Crovalimab 💬 |
Crovalimab | 062 [2] 62, 109 💬 💬 |
4 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
C5 [1] C5 💬 |
Eculizumab Eculizumab 💬 |
Eculizumab | 011 [7] 11, 13, 14, 61, 62, 109, 222 💬 💬 |
5 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
C5 [1] C5 💬 |
Nomacopan Nomacopan 💬 |
Nomacopan | 062 [3] 62, 109, 162 💬 💬 |
6 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
C5 [1] C5 💬 |
Pozelimab Pozelimab 💬 |
Pozelimab | 011 [2] 11, 62 💬 💬 |
7 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
C5 [1] C5 💬 |
Ravulizumab Ravulizumab 💬 |
Ravulizumab | 002 [7] 2 , 11, 13, 50, 62, 66, 109 💬 💬 |
8 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
C5 [1] C5 💬 |
Vilobelimab Vilobelimab 💬 |
Vilobelimab | 043 [3] 43, 44, 269 💬 💬 |
9 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
C5 [1] C5 💬 |
Zilucoplan Zilucoplan 💬 |
Zilucoplan | 002 [3] 2 , 11, 62 💬 💬 |
10 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
Atropine Atropine 💬 |
Atropine | 002 [2] 2 , 299 💬 💬 |
11 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
Blarcamesine Blarcamesine 💬 |
Blarcamesine | 156 [1] 156 💬 💬 |
12 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
Chlorpromazine Chlorpromazine 💬 |
Chlorpromazine | 254 [1] 254 💬 💬 |
13 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
Oxybutynin Oxybutynin 💬 |
Oxybutynin | 006 [3] 6 , 13, 53 💬 💬 |
14 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
Propiverine Propiverine 💬 |
Propiverine | 226 [1] 226 💬 💬 |
15 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
Scopolamine Scopolamine 💬 |
Scopolamine | 002 [1] 2 💬 💬 |
16 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
Trihexyphenidyl Trihexyphenidyl 💬 |
Trihexyphenidyl | 005 [2] 5 , 6 💬 💬 |
17 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
Tropicamide Tropicamide 💬 |
Tropicamide | 006 [1] 6 💬 💬 |
18 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
CHRM2 [2] CHRM2, CHRM3 💬 |
Fesoterodine Fesoterodine 💬 |
Fesoterodine | 006 [1] 6 💬 💬 |
19 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
CHRM2 [2] CHRM2, CHRM3 💬 |
Pilocarpine Pilocarpine 💬 |
Pilocarpine | 006 [3] 6 , 53, 299 💬 💬 |
20 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
CHRM3 [1] CHRM3 💬 |
Cevimeline Cevimeline 💬 |
Cevimeline | 053 [1] 53 💬 💬 |
21 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
CHRM3 [1] CHRM3 💬 |
Darifenacin Darifenacin 💬 |
Darifenacin | 006 [2] 6 , 13 💬 💬 |
22 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
CHRM3 [1] CHRM3 💬 |
Solifenacin Solifenacin 💬 |
Solifenacin | 006 [3] 6 , 13, 53 💬 💬 |
23 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
CHRM3 [1] CHRM3 💬 |
Tolterodine Tolterodine 💬 |
Tolterodine | 017 [2] 17, 53 💬 💬 |
24 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
CXCR4 [1] CXCR4 💬 |
Plerixafor Plerixafor 💬 |
Plerixafor | 019 [5] 19, 20, 65, 285, 299 💬 💬 |
25 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
EGFR [1] EGFR 💬 |
Cetuximab Cetuximab 💬 |
Cetuximab | 051 [2] 51, 86 💬 💬 |
26 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
EGFR [1] EGFR 💬 |
Erlotinib Erlotinib 💬 |
Erlotinib | 094 [1] 94 💬 💬 |
27 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
EGFR [1] EGFR 💬 |
Gefitinib Gefitinib 💬 |
Gefitinib | 075 [1] 75 💬 💬 |
28 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
EGFR [1] EGFR 💬 |
Icotinib Icotinib 💬 |
Icotinib | 034 [1] 34 💬 💬 |
29 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
EGFR [1] EGFR 💬 |
Lapatinib Lapatinib 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 💬 |
30 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
EGFR [1] EGFR 💬 |
Neratinib Neratinib 💬 |
Neratinib | 034 [1] 34 💬 💬 |
31 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
EGFR [1] EGFR 💬 |
Tesevatinib Tesevatinib 💬 |
Tesevatinib | 067 [1] 67 💬 💬 |
32 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
F2 [1] F2 💬 |
Dabigatran Dabigatran 💬 |
Dabigatran | 051 [5] 51, 75, 85, 91, 124 💬 💬 |
33 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
F2 [1] F2 💬 |
Dabigatran etexilate Dabigatran etexilate 💬 |
Dabigatran etexilate | 051 [2] 51, 75 💬 💬 |
34 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
F2 [1] F2 💬 |
Thrombomodulin alfa Thrombomodulin alfa 💬 |
Thrombomodulin Alfa | 085 [1] 85 💬 💬 |
35 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
FGF23 [1] FGF23 💬 |
Burosumab Burosumab 💬 |
Burosumab | 238 [1] 238 💬 💬 |
36 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
FGFR1 [3] FGFR1, FGFR2, FGFR3 💬 |
Infigratinib Infigratinib 💬 |
Infigratinib | 276 [1] 276 💬 💬 |
37 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
FGFR1 [5] FGFR1, FGFR2, FGFR3, PDGFRA, PDGFRB 💬 |
Nintedanib Nintedanib 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 💬 |
38 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
FGFR2 [1] FGFR2 💬 |
Palifermin Palifermin 💬 |
Palifermin | 013 [5] 13, 36, 38, 39, 65 💬 💬 |
39 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
ITGA4 [1] ITGA4 💬 |
Firategrast Firategrast 💬 |
Firategrast | 013 [1] 13 💬 💬 |
40 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
ITGA4 [1] ITGA4 💬 |
Natalizumab Natalizumab 💬 |
Natalizumab | 013 [6] 13, 15, 25, 46, 63, 96 💬 💬 |
41 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
ITGA4 [2] ITGA4, ITGB7 💬 |
Abrilumab Abrilumab 💬 |
Abrilumab | 096 [2] 96, 97 💬 💬 |
42 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
ITGA4 [2] ITGA4, ITGB7 💬 |
Vedolizumab Vedolizumab 💬 |
Vedolizumab | 094 [3] 94, 96, 97 💬 💬 |
43 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
ITGAL [1] ITGAL 💬 |
Efalizumab Efalizumab 💬 |
Efalizumab | 011 [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬 💬 |
44 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
ITGB7 [1] ITGB7 💬 |
Etrolizumab Etrolizumab 💬 |
Etrolizumab | 096 [2] 96, 97 💬 💬 |
45 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Binimetinib Binimetinib 💬 |
Binimetinib | 034 [1] 34 💬 💬 |
46 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Cobimetinib Cobimetinib 💬 |
Cobimetinib | 280 [1] 280 💬 💬 |
47 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Mirdametinib Mirdametinib 💬 |
Mirdametinib | 034 [1] 34 💬 💬 |
48 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Selumetinib Selumetinib 💬 |
Selumetinib | 034 [1] 34 💬 💬 |
49 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Trametinib Trametinib 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 💬 |
50 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
PDGFRA [1] PDGFRA 💬 |
Imatinib Imatinib 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬 |
51 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
Nilotinib Nilotinib 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 💬 |
52 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
Sunitinib Sunitinib 💬 |
Sunitinib | 028 [2] 28, 34 💬 💬 |
53 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
PDGFRB [2] PDGFRB, SRC 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
54 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
PDGFRB [2] PDGFRB, SRC 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
55 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
PIK3CA [1] PIK3CA 💬 |
Alpelisib Alpelisib 💬 |
Alpelisib | 138 [1] 138 💬 💬 |
56 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
Leniolisib Leniolisib 💬 |
Leniolisib | 053 [2] 53, 65 💬 💬 |
57 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
PIK3CD [1] PIK3CD 💬 |
Parsaclisib Parsaclisib 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 💬 |
58 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
ROCK1 [2] ROCK1, ROCK2 💬 |
Fasudil Fasudil 💬 |
Fasudil | 002 [4] 2 , 5 , 7 , 51 💬 💬 |
59 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
ROCK2 [1] ROCK2 💬 |
Belumosudil Belumosudil 💬 |
Belumosudil | 051 [2] 51, 85 💬 💬 |
60 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
SRC [1] SRC 💬 |
Bosutinib Bosutinib 💬 |
Bosutinib | 002 [2] 2 , 67 💬 💬 |
61 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
SRC [1] SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |