Target Gene/Pathway Pathway / Gene

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KEGG GENES

KEGG PATHWAY

KEGG DRUG

DrugBank

Disease ID

1

[11] Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extrac ...

Eculizumab 💬

[7] 11, 13, 14, 61, 62, 109, 222 💬

Disease ID	Name
11	Myasthenia gravis
13	Multiple sclerosis/Neuromyelitis optica
14	Chronic inflammatory demyelinating polyneuropathy
61	Autoimmune hemolytic anemia
62	Paroxysmal nocturnal hemoglobinuria
109	Atypical hemolytic uremic syndrome
222	Primary nephrotic syndrome

2

[11] Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extrac ...

Ravulizumab 💬

[7] 2, 11, 13, 50, 62, 66, 109 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
11	Myasthenia gravis
13	Multiple sclerosis/Neuromyelitis optica
50	Dermatomyositis
62	Paroxysmal nocturnal hemoglobinuria
66	IgA nephropathy
109	Atypical hemolytic uremic syndrome

3

[11] Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extrac ...

[3] 62, 109, 162 💬

4

[11] Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extrac ...

[2] 11, 62 💬

5

[11] Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extrac ...

Crovalimab 💬

[2] 62, 109 💬

6

[11] Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extrac ...

Vilobelimab 💬

[3] 43, 44, 269 💬

7

[11] Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extrac ...

Zilucoplan 💬

[3] 2, 11, 62 💬

8

[6] Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extrace ...

[3] 43, 44, 222 💬

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