Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY KEGG GENES KEGG DRUG DrugBank Disease ID
1 Systemic lupus erythematosus 💬
 [2] C1R, C1S 💬 Conestat alfa 💬 Conestat alfa [1] 61 💬 💬
2 Systemic lupus erythematosus 💬
 [1] C1S 💬 Sutimlimab 💬 Sutimlimab [1] 61 💬 💬
3 Systemic lupus erythematosus 💬
 [1] C3 💬 Pegcetacoplan 💬 Pegcetacoplan [4]  2 , 61, 62, 222 💬 💬
4 Systemic lupus erythematosus 💬
 [1] C5 💬 Crovalimab 💬 Crovalimab [2] 62, 109 💬 💬
5 Systemic lupus erythematosus 💬
 [1] C5 💬 Eculizumab 💬 Eculizumab [7] 11, 13, 14, 61, 62, 109, 222 💬 💬
6 Systemic lupus erythematosus 💬
 [1] C5 💬 Nomacopan 💬 Nomacopan [3] 62, 109, 162 💬 💬
7 Systemic lupus erythematosus 💬
 [1] C5 💬 Pozelimab 💬 Pozelimab [2] 11, 62 💬 💬
8 Systemic lupus erythematosus 💬
 [1] C5 💬 Ravulizumab 💬 Ravulizumab [7]  2 , 11, 13, 50, 62, 66, 109 💬 💬
9 Systemic lupus erythematosus 💬
 [1] C5 💬 Vilobelimab 💬 Vilobelimab [3] 43, 44, 269 💬 💬
10 Systemic lupus erythematosus 💬
 [1] C5 💬 Zilucoplan 💬 Zilucoplan [3]  2 , 11, 62 💬 💬
11 Systemic lupus erythematosus 💬
 [1] CD40 💬 Bleselumab 💬 Bleselumab [1] 222 💬 💬
12 Systemic lupus erythematosus 💬
 [1] CD40 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬 💬
13 Systemic lupus erythematosus 💬
 [1] CD40 💬 Ravagalimab 💬 Ravagalimab [2] 53, 97 💬 💬
14 Systemic lupus erythematosus 💬
 [1] CD40LG 💬 Toralizumab 💬 Toralizumab [1] 63 💬 💬
15 Systemic lupus erythematosus 💬
 [2] CD80, CD86 💬 Abatacept 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 💬
16 Systemic lupus erythematosus 💬
 [2] CD80, CD86 💬 Belatacept 💬 Belatacept [1] 46 💬 💬
17 Systemic lupus erythematosus 💬
 [1] ELANE 💬 Sivelestat 💬 Sivelestat [3] 13, 85, 96 💬 💬
18 Systemic lupus erythematosus 💬
 [2] GRIN2A, GRIN2B 💬 Acamprosate 💬 Acamprosate [2]  6 , 206 💬 💬
19 Systemic lupus erythematosus 💬
 [2] GRIN2A, GRIN2B 💬 Amantadine 💬 Amantadine [4]  6 ,  8 , 13, 127 💬 💬
20 Systemic lupus erythematosus 💬
 [2] GRIN2A, GRIN2B 💬 Dextromethorphan 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
21 Systemic lupus erythematosus 💬
 [2] GRIN2A, GRIN2B 💬 Esketamine 💬 Esketamine [3]  2 ,  4 , 70 💬 💬
22 Systemic lupus erythematosus 💬
 [2] GRIN2A, GRIN2B 💬 Ketamine 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬
23 Systemic lupus erythematosus 💬
 [2] GRIN2A, GRIN2B 💬 Latrepirdine 💬 Latrepirdine [1]  8  💬 💬
24 Systemic lupus erythematosus 💬
 [2] GRIN2A, GRIN2B 💬 Memantine 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬 💬
25 Systemic lupus erythematosus 💬
 [2] GRIN2A, GRIN2B 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬 💬
26 Systemic lupus erythematosus 💬
 [1] IFNG 💬 Emapalumab 💬 Emapalumab [3] 49, 65, 107 💬 💬
27 Systemic lupus erythematosus 💬
 [1] IFNG 💬 Fontolizumab 💬 Fontolizumab [1] 46 💬 💬
28 Systemic lupus erythematosus 💬
 [2] IL10, TNF 💬 Pirfenidone 💬 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬
29 Systemic lupus erythematosus 💬
 [1] TNF 💬 Adalimumab 💬 Adalimumab [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬
30 Systemic lupus erythematosus 💬
 [1] TNF 💬 Certolizumab pegol 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬
31 Systemic lupus erythematosus 💬
 [1] TNF 💬 Etanercept 💬 Etanercept [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 💬
32 Systemic lupus erythematosus 💬
 [1] TNF 💬 Golimumab 💬 Golimumab [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 💬
33 Systemic lupus erythematosus 💬
 [1] TNF 💬 Infliximab 💬 Infliximab [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬
34 Systemic lupus erythematosus 💬
 [1] TNF 💬 Lenalidomide 💬 Lenalidomide [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 💬
35 Systemic lupus erythematosus 💬
 [1] TNF 💬 Ozoralizumab 💬 Ozoralizumab [1] 46 💬 💬
36 Systemic lupus erythematosus 💬
 [1] TNF 💬 Pegsunercept 💬 Pegsunercept [1] 46 💬 💬
37 Systemic lupus erythematosus 💬
 [1] TNF 💬 Pomalidomide 💬 Pomalidomide [5] 28, 51, 85, 227, 331 💬 💬
38 Systemic lupus erythematosus 💬
 [1] TNF 💬 Thalidomide 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬