Target Gene/Pathway Pathway / Gene


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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 SV2C 1件: ECM-receptor interaction D11842 Padsevonil 1件: 149
2 ITGA4 11件: PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Hematopoietic cell lineage, Leukocyte transendothelial migration, Intestinal immune network for IgA production, Regulation of actin cytoskeleton, Yersinia infection, Leishmaniasis, Human papillomavirus infection, Hypertrophic cardiomyopathy D06590 Firategrast 1件: 13
3 ITGA4 11件: PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Hematopoietic cell lineage, Leukocyte transendothelial migration, Intestinal immune network for IgA production, Regulation of actin cytoskeleton, Yersinia infection, Leishmaniasis, Human papillomavirus infection, Hypertrophic cardiomyopathy D06886 Natalizumab 6件: 13, 15, 25, 46, 63, 96
4 ITGA4 11件: PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Hematopoietic cell lineage, Leukocyte transendothelial migration, Intestinal immune network for IgA production, Regulation of actin cytoskeleton, Yersinia infection, Leishmaniasis, Human papillomavirus infection, Hypertrophic cardiomyopathy D08083 Vedolizumab 3件: 94, 96, 97
5 ITGA4 11件: PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Hematopoietic cell lineage, Leukocyte transendothelial migration, Intestinal immune network for IgA production, Regulation of actin cytoskeleton, Yersinia infection, Leishmaniasis, Human papillomavirus infection, Hypertrophic cardiomyopathy D10540 Abrilumab 2件: 96, 97
6 ITGB7 8件: PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Intestinal immune network for IgA production, Regulation of actin cytoskeleton, Human papillomavirus infection, Transcriptional misregulation in cancer, Hypertrophic cardiomyopathy D08083 Vedolizumab 3件: 94, 96, 97
7 ITGB7 8件: PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Intestinal immune network for IgA production, Regulation of actin cytoskeleton, Human papillomavirus infection, Transcriptional misregulation in cancer, Hypertrophic cardiomyopathy D09901 Etrolizumab 2件: 96, 97
8 ITGB7 8件: PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Intestinal immune network for IgA production, Regulation of actin cytoskeleton, Human papillomavirus infection, Transcriptional misregulation in cancer, Hypertrophic cardiomyopathy D10540 Abrilumab 2件: 96, 97
9 VWF 6件: PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Platelet activation, Neutrophil extracellular trap formation, Human papillomavirus infection D11160 Caplacizumab 1件: 64
10 SV2B 1件: ECM-receptor interaction D11842 Padsevonil 1件: 149
11 SV2A 1件: ECM-receptor interaction D00709 Levetiracetam 5件: 2, 4, 6, 13, 307
12 SV2A 1件: ECM-receptor interaction D08879 Brivaracetam 2件: 149, 309
13 SV2A 1件: ECM-receptor interaction D11842 Padsevonil 1件: 149