Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	EDNRA	7件: Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligan ...	D01227	Bosentan	10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212
2	EDNRA	7件: Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligan ...	D07077	Ambrisentan	7件: 51, 84, 85, 86, 88, 210, 211
3	EDNRA	7件: Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligan ...	D07171	Sitaxentan	1件: 86
4	EDNRA	7件: Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligan ...	D07538	Bosentan	10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212
5	EDNRA	7件: Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligan ...	D07741	Zibotentan	1件: 51
6	EDNRA	7件: Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligan ...	D10135	Macitentan	5件: 51, 85, 86, 88, 210
7	EDNRA	7件: Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligan ...	D11776	Sparsentan	3件: 66, 218, 222

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