Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	TNF	67件: Antifolate resistance, MAPK signaling pathway, Cytokine-cytokine receptor interaction, Viral pr ...	D00742	Etanercept	16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285
2	TNF	67件: Antifolate resistance, MAPK signaling pathway, Cytokine-cytokine receptor interaction, Viral pr ...	D00754	Thalidomide	20件: 2, 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331
3	TNF	67件: Antifolate resistance, MAPK signaling pathway, Cytokine-cytokine receptor interaction, Viral pr ...	D01583	Pirfenidone	11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
4	TNF	67件: Antifolate resistance, MAPK signaling pathway, Cytokine-cytokine receptor interaction, Viral pr ...	D02597	Adalimumab	17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271
5	TNF	67件: Antifolate resistance, MAPK signaling pathway, Cytokine-cytokine receptor interaction, Viral pr ...	D02598	Infliximab	27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 1 ...
6	TNF	67件: Antifolate resistance, MAPK signaling pathway, Cytokine-cytokine receptor interaction, Viral pr ...	D03441	Certolizumab pegol	8件: 37, 46, 49, 96, 97, 107, 226, 271
7	TNF	67件: Antifolate resistance, MAPK signaling pathway, Cytokine-cytokine receptor interaction, Viral pr ...	D04358	Golimumab	8件: 46, 56, 84, 96, 97, 107, 270, 271
8	TNF	67件: Antifolate resistance, MAPK signaling pathway, Cytokine-cytokine receptor interaction, Viral pr ...	D04687	Lenalidomide	8件: 16, 26, 28, 34, 49, 284, 300, 331
9	TNF	67件: Antifolate resistance, MAPK signaling pathway, Cytokine-cytokine receptor interaction, Viral pr ...	D05393	Pegsunercept	1件: 46
10	TNF	67件: Antifolate resistance, MAPK signaling pathway, Cytokine-cytokine receptor interaction, Viral pr ...	D08976	Pomalidomide	5件: 28, 51, 85, 227, 331

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