Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	Disease ID
1	CYP11A1	[6] Steroid hormone biosynthesis, Metabolic pathways, Ovarian steroidogenesis, Aldosterone synthesis ...	D10950	Levoketoconazole	[1] 75
2	CYP11B2	[3] Steroid hormone biosynthesis, Metabolic pathways, Aldosterone synthesis and secretion	D11061	Osilodrostat	[1] 75
3	AGTR1	[14] Calcium signaling pathway, cGMP-PKG signaling pathway, Phospholipase D signaling pathway, Neuro ...	D00150	Angiotensin II	[7] 17, 19, 46, 66, 86, 222, 224
4	AGTR1	[14] Calcium signaling pathway, cGMP-PKG signaling pathway, Phospholipase D signaling pathway, Neuro ...	D00400	Valsartan	[7] 57, 58, 66, 75, 218, 222, 224
5	AGTR1	[14] Calcium signaling pathway, cGMP-PKG signaling pathway, Phospholipase D signaling pathway, Neuro ...	D00522	Candesartan	[2] 58, 67
6	AGTR1	[14] Calcium signaling pathway, cGMP-PKG signaling pathway, Phospholipase D signaling pathway, Neuro ...	D00523	Irbesartan	[4] 66, 167, 168, 222
7	AGTR1	[14] Calcium signaling pathway, cGMP-PKG signaling pathway, Phospholipase D signaling pathway, Neuro ...	D00626	Candesartan cilexetil	[1] 67
8	AGTR1	[14] Calcium signaling pathway, cGMP-PKG signaling pathway, Phospholipase D signaling pathway, Neuro ...	D00627	Telmisartan	[2] 66, 67
9	AGTR1	[14] Calcium signaling pathway, cGMP-PKG signaling pathway, Phospholipase D signaling pathway, Neuro ...	D02014	Angiotensin II	[7] 17, 19, 46, 66, 86, 222, 224
10	AGTR1	[14] Calcium signaling pathway, cGMP-PKG signaling pathway, Phospholipase D signaling pathway, Neuro ...	D08146	Losartan	[17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299

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