Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 MAPK14 19件: Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer D09639 Losmapimod 2件: 113, 222
2 MAPK14 19件: Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer D10959 Neflamapimod 1件: 8
3 EGFR 6件: Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Proteoglycans in cancer D01977 Gefitinib 1件: 75
4 EGFR 6件: Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Proteoglycans in cancer D03455 Cetuximab 5件: 34, 51, 86, 89, 331
5 EGFR 6件: Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Proteoglycans in cancer D04023 Erlotinib 1件: 94
6 EGFR 6件: Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Proteoglycans in cancer D04024 Lapatinib 3件: 34, 74, 75
7 EGFR 6件: Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Proteoglycans in cancer D07907 Erlotinib 1件: 94
8 EGFR 6件: Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Proteoglycans in cancer D08108 Lapatinib 3件: 34, 74, 75
9 EGFR 6件: Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Proteoglycans in cancer D11251 Icotinib 1件: 34
10 EGFR 6件: Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Proteoglycans in cancer D11772 Tesevatinib 1件: 67
11 ERBB2 2件: Tight junction, Proteoglycans in cancer D04024 Lapatinib 3件: 34, 74, 75
12 ERBB2 2件: Tight junction, Proteoglycans in cancer D08108 Lapatinib 3件: 34, 74, 75
13 ERBB2 2件: Tight junction, Proteoglycans in cancer D11772 Tesevatinib 1件: 67
14 ESR1 2件: Thyroid hormone signaling pathway, Proteoglycans in cancer D00105 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
15 ESR1 2件: Thyroid hormone signaling pathway, Proteoglycans in cancer D00185 Estriol 2件: 13, 227
16 ESR1 2件: Thyroid hormone signaling pathway, Proteoglycans in cancer D00289 Danazol 5件: 60, 63, 64, 65, 285
17 ESR1 2件: Thyroid hormone signaling pathway, Proteoglycans in cancer D00554 Ethinylestradiol 4件: 13, 46, 49, 299
18 ESR1 2件: Thyroid hormone signaling pathway, Proteoglycans in cancer D00575 Mestranol 2件: 46, 49
19 ESR1 2件: Thyroid hormone signaling pathway, Proteoglycans in cancer D00962 Clomifene 1件: 74
20 ESR1 2件: Thyroid hormone signaling pathway, Proteoglycans in cancer D00966 Tamoxifen 4件: 2, 86, 113, 227
21 ESR1 2件: Thyroid hormone signaling pathway, Proteoglycans in cancer D01161 Fulvestrant 2件: 49, 86
22 ESR1 2件: Thyroid hormone signaling pathway, Proteoglycans in cancer D01413 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
23 ESR1 2件: Thyroid hormone signaling pathway, Proteoglycans in cancer D01413 Estradiol valerate 1件: 65
24 ESR1 2件: Thyroid hormone signaling pathway, Proteoglycans in cancer D01617 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
25 ESR1 2件: Thyroid hormone signaling pathway, Proteoglycans in cancer D01953 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
26 ESR1 2件: Thyroid hormone signaling pathway, Proteoglycans in cancer D01986 Estriol 2件: 13, 227
27 ESR1 2件: Thyroid hormone signaling pathway, Proteoglycans in cancer D02217 Raloxifene 1件: 46
28 ESR1 2件: Thyroid hormone signaling pathway, Proteoglycans in cancer D02367 Desogestrel 1件: 230
29 ESR1 2件: Thyroid hormone signaling pathway, Proteoglycans in cancer D04061 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
30 ESR1 2件: Thyroid hormone signaling pathway, Proteoglycans in cancer D04063 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
31 ESR1 2件: Thyroid hormone signaling pathway, Proteoglycans in cancer D04064 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
32 ESR1 2件: Thyroid hormone signaling pathway, Proteoglycans in cancer D04065 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
33 ESR1 2件: Thyroid hormone signaling pathway, Proteoglycans in cancer D07726 Clomifene 1件: 74
34 ESR1 2件: Thyroid hormone signaling pathway, Proteoglycans in cancer D08409 Prasterone 6件: 49, 53, 83, 86, 96, 113
35 ESR1 2件: Thyroid hormone signaling pathway, Proteoglycans in cancer D08465 Raloxifene 1件: 46
36 ESR1 2件: Thyroid hormone signaling pathway, Proteoglycans in cancer D08559 Tamoxifen 4件: 2, 86, 113, 227
37 ESR1 2件: Thyroid hormone signaling pathway, Proteoglycans in cancer D11513 Estetrol 1件: 53
38 ESR1 2件: Thyroid hormone signaling pathway, Proteoglycans in cancer D11514 Estetrol 1件: 53
39 FGFR1 6件: Ras signaling pathway, Rap1 signaling pathway, Signaling pathways regulating pluripotency of stem cells, Thermogenesis, Regulation of actin cytoskeleton, Proteoglycans in cancer D10481 Nintedanib 5件: 51, 85, 89, 227, 228
40 FGFR1 6件: Ras signaling pathway, Rap1 signaling pathway, Signaling pathways regulating pluripotency of stem cells, Thermogenesis, Regulation of actin cytoskeleton, Proteoglycans in cancer D11589 Infigratinib 1件: 276
41 MTOR 7件: Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Proteoglycans in cancer D00753 Sirolimus 41件: 2, 6, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
42 MTOR 7件: Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Proteoglycans in cancer D02714 Everolimus 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277
43 MTOR 7件: Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Proteoglycans in cancer D06068 Temsirolimus 4件: 13, 34, 89, 331
44 IGF1R 5件: Ras signaling pathway, Rap1 signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer, Proteoglycans in cancer D03297 Mecasermin 6件: 65, 78, 96, 168, 265, 299
45 IGF1R 5件: Ras signaling pathway, Rap1 signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer, Proteoglycans in cancer D04870 Mecasermin 6件: 65, 78, 96, 168, 265, 299
46 IGF1R 5件: Ras signaling pathway, Rap1 signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer, Proteoglycans in cancer D09680 Teprotumumab 1件: 51
47 IGF1R 5件: Ras signaling pathway, Rap1 signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer, Proteoglycans in cancer D09925 Linsitinib 1件: 232
48 IL12B 7件: Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer D09214 Ustekinumab 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271
49 KDR 4件: Ras signaling pathway, Rap1 signaling pathway, VEGF signaling pathway, Proteoglycans in cancer D03218 Axitinib 1件: 34
50 KDR 4件: Ras signaling pathway, Rap1 signaling pathway, VEGF signaling pathway, Proteoglycans in cancer D06272 Sorafenib 2件: 34, 86
51 KDR 4件: Ras signaling pathway, Rap1 signaling pathway, VEGF signaling pathway, Proteoglycans in cancer D06402 Sunitinib 2件: 28, 34
52 KDR 4件: Ras signaling pathway, Rap1 signaling pathway, VEGF signaling pathway, Proteoglycans in cancer D08524 Sorafenib 2件: 34, 86
53 KDR 4件: Ras signaling pathway, Rap1 signaling pathway, VEGF signaling pathway, Proteoglycans in cancer D08552 Sunitinib 2件: 28, 34
54 KDR 4件: Ras signaling pathway, Rap1 signaling pathway, VEGF signaling pathway, Proteoglycans in cancer D08881 Cediranib 1件: 34
55 KDR 4件: Ras signaling pathway, Rap1 signaling pathway, VEGF signaling pathway, Proteoglycans in cancer D10062 Cabozantinib 1件: 34
56 KDR 4件: Ras signaling pathway, Rap1 signaling pathway, VEGF signaling pathway, Proteoglycans in cancer D10481 Nintedanib 5件: 51, 85, 89, 227, 228
57 KDR 4件: Ras signaling pathway, Rap1 signaling pathway, VEGF signaling pathway, Proteoglycans in cancer D11772 Tesevatinib 1件: 67
58 MET 5件: Ras signaling pathway, Rap1 signaling pathway, Transcriptional misregulation in cancer, Proteoglycans in cancer, Renal cell carcinoma D10062 Cabozantinib 1件: 34
59 PIK3CA 21件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Proteoglycans in cancer, Renal cell carcinoma, Small cell lung cancer D11158 Leniolisib 2件: 53, 65
60 PIK3CB 21件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Proteoglycans in cancer, Renal cell carcinoma, Small cell lung cancer D11158 Leniolisib 2件: 53, 65
61 PIK3CD 21件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Proteoglycans in cancer, Renal cell carcinoma, Small cell lung cancer D11158 Leniolisib 2件: 53, 65
62 PIK3CD 21件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Proteoglycans in cancer, Renal cell carcinoma, Small cell lung cancer D11437 Parsaclisib 3件: 35, 53, 61
63 MAPK11 19件: Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer D09639 Losmapimod 2件: 113, 222
64 MAPK11 19件: Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer D10959 Neflamapimod 1件: 8
65 MAPK13 19件: Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer D09639 Losmapimod 2件: 113, 222
66 MAPK13 19件: Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer D10959 Neflamapimod 1件: 8
67 MAP2K1 18件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Thyroid cancer D09666 Selumetinib 1件: 34
68 MAP2K1 18件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Thyroid cancer D10175 Trametinib 4件: 2, 34, 279, 280
69 MAP2K1 18件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Thyroid cancer D10405 Cobimetinib 1件: 280
70 MAP2K1 18件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Thyroid cancer D10604 Binimetinib 1件: 34
71 MAP2K2 16件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Thyroid cancer D09666 Selumetinib 1件: 34
72 MAP2K2 16件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Thyroid cancer D10175 Trametinib 4件: 2, 34, 279, 280
73 MAP2K2 16件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Thyroid cancer D10405 Cobimetinib 1件: 280
74 MAP2K2 16件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Thyroid cancer D10604 Binimetinib 1件: 34
75 RAF1 15件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, T cell receptor signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Tuberculosis, Proteoglycans in cancer, Renal cell carcinoma D06272 Sorafenib 2件: 34, 86
76 RAF1 15件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, T cell receptor signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Tuberculosis, Proteoglycans in cancer, Renal cell carcinoma D08524 Sorafenib 2件: 34, 86
77 ROCK1 8件: Sphingolipid signaling pathway, Vascular smooth muscle contraction, TGF-beta signaling pathway, Tight junction, Regulation of actin cytoskeleton, Shigellosis, Yersinia infection, Proteoglycans in cancer D07941 Fasudil 4件: 2, 5, 7, 51
78 MAPK12 19件: Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer D09639 Losmapimod 2件: 113, 222
79 MAPK12 19件: Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer D10959 Neflamapimod 1件: 8
80 SMO 1件: Proteoglycans in cancer D09992 Vismodegib 1件: 85
81 SMO 1件: Proteoglycans in cancer D10671 Taladegib 1件: 85
82 SRC 11件: Rap1 signaling pathway, VEGF signaling pathway, Tight junction, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Shigellosis, Yersinia infection, Tuberculosis, Viral carcinogenesis, Proteoglycans in cancer D03252 Bosutinib 2件: 2, 67
83 SRC 11件: Rap1 signaling pathway, VEGF signaling pathway, Tight junction, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Shigellosis, Yersinia infection, Tuberculosis, Viral carcinogenesis, Proteoglycans in cancer D03658 Dasatinib 2件: 51, 85
84 SRC 11件: Rap1 signaling pathway, VEGF signaling pathway, Tight junction, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Shigellosis, Yersinia infection, Tuberculosis, Viral carcinogenesis, Proteoglycans in cancer D06414 Dasatinib 2件: 51, 85
85 SRC 11件: Rap1 signaling pathway, VEGF signaling pathway, Tight junction, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Shigellosis, Yersinia infection, Tuberculosis, Viral carcinogenesis, Proteoglycans in cancer D09664 Saracatinib 3件: 6, 89, 272
86 BRAF 7件: Rap1 signaling pathway, Vascular smooth muscle contraction, Serotonergic synapse, Regulation of actin cytoskeleton, Proteoglycans in cancer, Renal cell carcinoma, Thyroid cancer D06272 Sorafenib 2件: 34, 86
87 BRAF 7件: Rap1 signaling pathway, Vascular smooth muscle contraction, Serotonergic synapse, Regulation of actin cytoskeleton, Proteoglycans in cancer, Renal cell carcinoma, Thyroid cancer D08524 Sorafenib 2件: 34, 86
88 BRAF 7件: Rap1 signaling pathway, Vascular smooth muscle contraction, Serotonergic synapse, Regulation of actin cytoskeleton, Proteoglycans in cancer, Renal cell carcinoma, Thyroid cancer D10064 Dabrafenib 1件: 34
89 TGFB1 8件: TGF-beta signaling pathway, Th17 cell differentiation, Relaxin signaling pathway, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, Renal cell carcinoma, Rheumatoid arthritis D09620 Fresolimumab 4件: 51, 85, 222, 274
90 TGFB2 6件: TGF-beta signaling pathway, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, Renal cell carcinoma, Rheumatoid arthritis D09620 Fresolimumab 4件: 51, 85, 222, 274
91 TNF 17件: Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, Systemic lupus erythematosus, Rheumatoid arthritis D00742 Etanercept 17件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298
92 TNF 17件: Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, Systemic lupus erythematosus, Rheumatoid arthritis D00754 Thalidomide 20件: 2, 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331
93 TNF 17件: Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, Systemic lupus erythematosus, Rheumatoid arthritis D01583 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
94 TNF 17件: Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, Systemic lupus erythematosus, Rheumatoid arthritis D02597 Adalimumab 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271
95 TNF 17件: Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, Systemic lupus erythematosus, Rheumatoid arthritis D02598 Infliximab 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271
96 TNF 17件: Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, Systemic lupus erythematosus, Rheumatoid arthritis D03441 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271
97 TNF 17件: Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, Systemic lupus erythematosus, Rheumatoid arthritis D04358 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271
98 TNF 17件: Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, Systemic lupus erythematosus, Rheumatoid arthritis D04687 Lenalidomide 8件: 16, 26, 28, 34, 49, 284, 300, 331
99 TNF 17件: Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, Systemic lupus erythematosus, Rheumatoid arthritis D05393 Pegsunercept 1件: 46
100 TNF 17件: Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, Systemic lupus erythematosus, Rheumatoid arthritis D08976 Pomalidomide 6件: 28, 34, 51, 85, 227, 331
101 TNF 17件: Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, Systemic lupus erythematosus, Rheumatoid arthritis D09944 Ozoralizumab 1件: 46
102 VEGFA 7件: Ras signaling pathway, Rap1 signaling pathway, VEGF signaling pathway, Relaxin signaling pathway, Proteoglycans in cancer, Renal cell carcinoma, Rheumatoid arthritis D05697 Ranibizumab 4件: 34, 166, 227, 301
103 VEGFA 7件: Ras signaling pathway, Rap1 signaling pathway, VEGF signaling pathway, Relaxin signaling pathway, Proteoglycans in cancer, Renal cell carcinoma, Rheumatoid arthritis D06409 Bevacizumab 9件: 13, 34, 85, 86, 87, 89, 227, 280, 331
104 VEGFA 7件: Ras signaling pathway, Rap1 signaling pathway, VEGF signaling pathway, Relaxin signaling pathway, Proteoglycans in cancer, Renal cell carcinoma, Rheumatoid arthritis D09574 Aflibercept 2件: 90, 166
105 ROCK2 9件: Sphingolipid signaling pathway, Vascular smooth muscle contraction, Wnt signaling pathway, Tight junction, Regulation of actin cytoskeleton, Shigellosis, Salmonella infection, Yersinia infection, Proteoglycans in cancer D07941 Fasudil 4件: 2, 5, 7, 51
106 ROCK2 9件: Sphingolipid signaling pathway, Vascular smooth muscle contraction, Wnt signaling pathway, Tight junction, Regulation of actin cytoskeleton, Shigellosis, Salmonella infection, Yersinia infection, Proteoglycans in cancer D11815 Belumosudil 1件: 51