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KEGG GENES
KEGG PATHWAY
KEGG DRUG
DrugBank
指定難病告示番号
1
CDK4
💬
1. CDK4
×
Name
Full Name
CDK4
cyclin dependent kinase 4
28件:
Endocrine resistance
Endocrine resistance
,
Cell cycle
,
p53 signaling pathway
,
PI3K-Akt signaling pathway
,
Cellular senescence
,
Tight junction
,
T cell receptor signaling pathway
,
AGE-RAGE signaling pathway in diabetic complications
,
Cushing syndrome
,
Hepatitis C
,
Measles
,
Human cytomegalovirus infection
,
Influenza A
,
Human papillomavirus infection
,
Human T-cell leukemia virus 1 infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Epstein-Barr virus infection
,
Pathways in cancer
,
Viral carcinogenesis
,
Pancreatic cancer
,
Glioma
,
Melanoma
,
Bladder cancer
,
Chronic myeloid leukemia
,
Small cell lung cancer
,
Non-small cell lung cancer
,
Breast cancer
,
Hepatocellular carcinoma
28件:
Endocrine resistance
,
Cell cycle
,
p53 signaling pathway
,
PI3K-Akt signaling pathway
,
Cellular s
...
Abemaciclib
Abemaciclib
💬
1. CDK4
×
Name
Other Names
Abemaciclib
Abemaciclib (JAN/USAN)
Verzenio (TN)
アベマシクリブ
ベージニオ
Abemaciclib
1件:
34
34
💬
1. CDK4
×
告示番号
日本語名
英語名
34
神経線維腫症
Neurofibromatosis
2
CDK6
💬
2. CDK6
×
Name
Full Name
CDK6
cyclin dependent kinase 6
23件:
Cell cycle
Cell cycle
,
p53 signaling pathway
,
PI3K-Akt signaling pathway
,
Cellular senescence
,
Cushing syndrome
,
Hepatitis C
,
Measles
,
Human cytomegalovirus infection
,
Influenza A
,
Human papillomavirus infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Epstein-Barr virus infection
,
Pathways in cancer
,
Viral carcinogenesis
,
MicroRNAs in cancer
,
Pancreatic cancer
,
Glioma
,
Melanoma
,
Chronic myeloid leukemia
,
Small cell lung cancer
,
Non-small cell lung cancer
,
Breast cancer
,
Hepatocellular carcinoma
23件:
Cell cycle
,
p53 signaling pathway
,
PI3K-Akt signaling pathway
,
Cellular senescence
,
Cushing syn
...
Abemaciclib
Abemaciclib
💬
2. CDK6
×
Name
Other Names
Abemaciclib
Abemaciclib (JAN/USAN)
Verzenio (TN)
アベマシクリブ
ベージニオ
Abemaciclib
1件:
34
34
💬
2. CDK6
×
告示番号
日本語名
英語名
34
神経線維腫症
Neurofibromatosis
3
FDPS
💬
3. FDPS
×
Name
Full Name
FDPS
farnesyl diphosphate synthase
4件:
Terpenoid backbone biosynthesis
Terpenoid backbone biosynthesis
,
Metabolic pathways
,
Influenza A
,
Human T-cell leukemia virus 1 infection
4件:
Terpenoid backbone biosynthesis
,
Metabolic pathways
,
Influenza A
,
Human T-cell leukemia virus 1
...
Zoledronic acid
Zoledronic acid
💬
3. FDPS
×
Name
Other Names
Zoledronic acid
Zoledronic acid (USAN)
Zoledronic acid hydrate (JAN)
Zometa (TN)
Reclast (TN)
ゾレドロン酸水和物
ゾメタ
リクラスト
ゾレドロン酸
Zoledronic acid
13件:
5
5
,
6
,
13
,
17
,
46
,
65
,
93
,
95
,
96
,
270
,
274
,
299
,
333
💬
3. FDPS
×
告示番号
日本語名
英語名
5
進行性核上性麻痺
Progressive supranuclear palsy
6
パーキンソン病
Parkinson disease
13
多発性硬化症／視神経脊髄炎
Multiple sclerosis/Neuromyelitis optica
17
多系統萎縮症
Multiple system atrophy
46
悪性関節リウマチ
Malignant rheumatoid arthritis
65
原発性免疫不全症候群
Primary immunodeficiency
93
原発性胆汁性胆管炎
Primary biliary cholangitis
95
自己免疫性肝炎
Autoimmune hepatitis
96
クローン病;回腸末端炎
Crohn disease
270
慢性再発性多発性骨髄炎
Chronic recurrent multifocal osteomyelitis
274
骨形成不全症
Osteogenesis Imperfecta
299
嚢胞性線維症;膵囊胞線維症
Cystic fibrosis
333
ハッチンソン・ギルフォード症候群
Hutchinson-Gilford syndrome
4
FDPS
💬
4. FDPS
×
Name
Full Name
FDPS
farnesyl diphosphate synthase
4件:
Terpenoid backbone biosynthesis
Terpenoid backbone biosynthesis
,
Metabolic pathways
,
Influenza A
,
Human T-cell leukemia virus 1 infection
4件:
Terpenoid backbone biosynthesis
,
Metabolic pathways
,
Influenza A
,
Human T-cell leukemia virus 1
...
Alendronic acid
Alendronic acid
💬
4. FDPS
×
Name
Other Names
Alendronic acid
Alendronic acid (INN)
アレンドロン酸
Alendronic acid
7件:
19
19
,
41
,
46
,
50
,
271
,
274
,
299
💬
4. FDPS
×
告示番号
日本語名
英語名
19
ライソゾーム病
Lysosomal storage disease
41
巨細胞性動脈炎;側頭動脈炎
Giant cell arteritis
46
悪性関節リウマチ
Malignant rheumatoid arthritis
50
皮膚筋炎／多発性筋炎
Dermatomyositis
271
強直性脊椎炎
Ankylosing spondylitis
274
骨形成不全症
Osteogenesis Imperfecta
299
嚢胞性線維症;膵囊胞線維症
Cystic fibrosis
5
FDPS
💬
5. FDPS
×
Name
Full Name
FDPS
farnesyl diphosphate synthase
4件:
Terpenoid backbone biosynthesis
Terpenoid backbone biosynthesis
,
Metabolic pathways
,
Influenza A
,
Human T-cell leukemia virus 1 infection
4件:
Terpenoid backbone biosynthesis
,
Metabolic pathways
,
Influenza A
,
Human T-cell leukemia virus 1
...
Pamidronic acid
Pamidronic acid
💬
5. FDPS
×
Name
Other Names
Pamidronic acid
Pamidronic acid (INN)
Ribodroat (TN)
パミドロン酸
Pamidronic acid
3件:
270
270
,
271
,
274
💬
5. FDPS
×
告示番号
日本語名
英語名
270
慢性再発性多発性骨髄炎
Chronic recurrent multifocal osteomyelitis
271
強直性脊椎炎
Ankylosing spondylitis
274
骨形成不全症
Osteogenesis Imperfecta
6
FDPS
💬
6. FDPS
×
Name
Full Name
FDPS
farnesyl diphosphate synthase
4件:
Terpenoid backbone biosynthesis
Terpenoid backbone biosynthesis
,
Metabolic pathways
,
Influenza A
,
Human T-cell leukemia virus 1 infection
4件:
Terpenoid backbone biosynthesis
,
Metabolic pathways
,
Influenza A
,
Human T-cell leukemia virus 1
...
Risedronic acid
Risedronic acid
💬
6. FDPS
×
Name
Other Names
Risedronic acid
Risedronic acid (INN)
Ridron (TN)
リセドロン酸
Risedronic acid
9件:
46
46
,
50
,
66
,
93
,
95
,
96
,
107
,
113
,
274
💬
6. FDPS
×
告示番号
日本語名
英語名
46
悪性関節リウマチ
Malignant rheumatoid arthritis
50
皮膚筋炎／多発性筋炎
Dermatomyositis
66
IgA腎症
IgA nephropathy
93
原発性胆汁性胆管炎
Primary biliary cholangitis
95
自己免疫性肝炎
Autoimmune hepatitis
96
クローン病;回腸末端炎
Crohn disease
107
若年性特発性関節炎
Juvenile idiopathic arthritis
113
筋ジストロフィー
Muscular dystrophy
274
骨形成不全症
Osteogenesis Imperfecta
7
FDPS
💬
7. FDPS
×
Name
Full Name
FDPS
farnesyl diphosphate synthase
4件:
Terpenoid backbone biosynthesis
Terpenoid backbone biosynthesis
,
Metabolic pathways
,
Influenza A
,
Human T-cell leukemia virus 1 infection
4件:
Terpenoid backbone biosynthesis
,
Metabolic pathways
,
Influenza A
,
Human T-cell leukemia virus 1
...
Zoledronic acid
Zoledronic acid
💬
7. FDPS
×
Name
Other Names
Zoledronic acid
Zoledronic acid (INN)
Zometa (TN)
Reclast (TN)
ゾレドロン酸
Zoledronic acid
13件:
5
5
,
6
,
13
,
17
,
46
,
65
,
93
,
95
,
96
,
270
,
274
,
299
,
333
💬
7. FDPS
×
告示番号
日本語名
英語名
5
進行性核上性麻痺
Progressive supranuclear palsy
6
パーキンソン病
Parkinson disease
13
多発性硬化症／視神経脊髄炎
Multiple sclerosis/Neuromyelitis optica
17
多系統萎縮症
Multiple system atrophy
46
悪性関節リウマチ
Malignant rheumatoid arthritis
65
原発性免疫不全症候群
Primary immunodeficiency
93
原発性胆汁性胆管炎
Primary biliary cholangitis
95
自己免疫性肝炎
Autoimmune hepatitis
96
クローン病;回腸末端炎
Crohn disease
270
慢性再発性多発性骨髄炎
Chronic recurrent multifocal osteomyelitis
274
骨形成不全症
Osteogenesis Imperfecta
299
嚢胞性線維症;膵囊胞線維症
Cystic fibrosis
333
ハッチンソン・ギルフォード症候群
Hutchinson-Gilford syndrome
8
IFNA1
💬
8. IFNA1
×
Name
Full Name
IFNA1
interferon alpha 1
25件:
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
PI3K-Akt signaling pathway
,
Necroptosis
,
Toll-like receptor signaling pathway
,
NOD-like receptor signaling pathway
,
RIG-I-like receptor signaling pathway
,
Cytosolic DNA-sensing pathway
,
JAK-STAT signaling pathway
,
Natural killer cell mediated cytotoxicity
,
Alcoholic liver disease
,
Tuberculosis
,
Hepatitis C
,
Hepatitis B
,
Measles
,
Human cytomegalovirus infection
,
Influenza A
,
Human papillomavirus infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Herpes simplex virus 1 infection
,
Epstein-Barr virus infection
,
Human immunodeficiency virus 1 infection
,
Coronavirus disease - COVID-19
,
Pathways in cancer
,
Autoimmune thyroid disease
,
Lipid and atherosclerosis
25件:
Cytokine-cytokine receptor interaction
,
PI3K-Akt signaling pathway
,
Necroptosis
,
Toll-like rece
...
Rontalizumab
Rontalizumab
💬
8. IFNA1
×
Name
Other Names
Rontalizumab
Rontalizumab (USAN/INN)
ロンタリズマブ
Rontalizumab
1件:
49
49
💬
8. IFNA1
×
告示番号
日本語名
英語名
49
全身性エリテマトーデス
Systemic lupus erythematosus
9
IFNA1
💬
9. IFNA1
×
Name
Full Name
IFNA1
interferon alpha 1
25件:
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
PI3K-Akt signaling pathway
,
Necroptosis
,
Toll-like receptor signaling pathway
,
NOD-like receptor signaling pathway
,
RIG-I-like receptor signaling pathway
,
Cytosolic DNA-sensing pathway
,
JAK-STAT signaling pathway
,
Natural killer cell mediated cytotoxicity
,
Alcoholic liver disease
,
Tuberculosis
,
Hepatitis C
,
Hepatitis B
,
Measles
,
Human cytomegalovirus infection
,
Influenza A
,
Human papillomavirus infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Herpes simplex virus 1 infection
,
Epstein-Barr virus infection
,
Human immunodeficiency virus 1 infection
,
Coronavirus disease - COVID-19
,
Pathways in cancer
,
Autoimmune thyroid disease
,
Lipid and atherosclerosis
25件:
Cytokine-cytokine receptor interaction
,
PI3K-Akt signaling pathway
,
Necroptosis
,
Toll-like rece
...
Sifalimumab
Sifalimumab
💬
9. IFNA1
×
Name
Other Names
Sifalimumab
Sifalimumab (USAN/INN)
シファリムマブ
Sifalimumab
1件:
49
49
💬
9. IFNA1
×
告示番号
日本語名
英語名
49
全身性エリテマトーデス
Systemic lupus erythematosus
10
IFNA2
💬
10. IFNA2
×
Name
Full Name
IFNA2
interferon alpha 2
25件:
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
PI3K-Akt signaling pathway
,
Necroptosis
,
Toll-like receptor signaling pathway
,
NOD-like receptor signaling pathway
,
RIG-I-like receptor signaling pathway
,
Cytosolic DNA-sensing pathway
,
JAK-STAT signaling pathway
,
Natural killer cell mediated cytotoxicity
,
Alcoholic liver disease
,
Tuberculosis
,
Hepatitis C
,
Hepatitis B
,
Measles
,
Human cytomegalovirus infection
,
Influenza A
,
Human papillomavirus infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Herpes simplex virus 1 infection
,
Epstein-Barr virus infection
,
Human immunodeficiency virus 1 infection
,
Coronavirus disease - COVID-19
,
Pathways in cancer
,
Autoimmune thyroid disease
,
Lipid and atherosclerosis
25件:
Cytokine-cytokine receptor interaction
,
PI3K-Akt signaling pathway
,
Necroptosis
,
Toll-like rece
...
Rontalizumab
Rontalizumab
💬
10. IFNA2
×
Name
Other Names
Rontalizumab
Rontalizumab (USAN/INN)
ロンタリズマブ
Rontalizumab
1件:
49
49
💬
10. IFNA2
×
告示番号
日本語名
英語名
49
全身性エリテマトーデス
Systemic lupus erythematosus