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KEGG GENES
KEGG PATHWAY
KEGG DRUG
DrugBank
指定難病告示番号
1
MAPK14
💬
1. MAPK14
×
Name
Full Name
MAPK14
mitogen-activated protein kinase 14
62件:
Endocrine resistance
Endocrine resistance
,
MAPK signaling pathway
,
Rap1 signaling pathway
,
FoxO signaling pathway
,
Sphingolipid signaling pathway
,
Oocyte meiosis
,
Cellular senescence
,
Adrenergic signaling in cardiomyocytes
,
VEGF signaling pathway
,
Osteoclast differentiation
,
Signaling pathways regulating pluripotency of stem cells
,
Platelet activation
,
Neutrophil extracellular trap formation
,
Toll-like receptor signaling pathway
,
NOD-like receptor signaling pathway
,
RIG-I-like receptor signaling pathway
,
C-type lectin receptor signaling pathway
,
IL-17 signaling pathway
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
T cell receptor signaling pathway
,
Fc epsilon RI signaling pathway
,
TNF signaling pathway
,
Leukocyte transendothelial migration
,
Thermogenesis
,
Neurotrophin signaling pathway
,
Retrograde endocannabinoid signaling
,
Dopaminergic synapse
,
Inflammatory mediator regulation of TRP channels
,
GnRH signaling pathway
,
Progesterone-mediated oocyte maturation
,
Prolactin signaling pathway
,
Relaxin signaling pathway
,
Non-alcoholic fatty liver disease
,
AGE-RAGE signaling pathway in diabetic complications
,
Growth hormone synthesis, secretion and action
,
Alcoholic liver disease
,
Amyotrophic lateral sclerosis
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Epithelial cell signaling in Helicobacter pylori infection
,
Pathogenic Escherichia coli infection
,
Shigellosis
,
Salmonella infection
,
Pertussis
,
Yersinia infection
,
Leishmaniasis
,
Chagas disease
,
Toxoplasmosis
,
Tuberculosis
,
Hepatitis B
,
Human cytomegalovirus infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Epstein-Barr virus infection
,
Human immunodeficiency virus 1 infection
,
Coronavirus disease - COVID-19
,
Proteoglycans in cancer
,
Chemical carcinogenesis - reactive oxygen species
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
Diabetic cardiomyopathy
,
Lipid and atherosclerosis
,
Fluid shear stress and atherosclerosis
62件:
Endocrine resistance
,
MAPK signaling pathway
,
Rap1 signaling pathway
,
FoxO signaling pathway
,
S
...
Losmapimod
Losmapimod
💬
1. MAPK14
×
Name
Other Names
Losmapimod
Losmapimod (USAN/INN)
ロスマピモド
Losmapimod
2件:
113
113
,
222
💬
1. MAPK14
×
告示番号
日本語名
英語名
113
筋ジストロフィー
Muscular dystrophy
222
一次性ネフローゼ症候群
Primary nephrotic syndrome
2
MAPK14
💬
2. MAPK14
×
Name
Full Name
MAPK14
mitogen-activated protein kinase 14
62件:
Endocrine resistance
Endocrine resistance
,
MAPK signaling pathway
,
Rap1 signaling pathway
,
FoxO signaling pathway
,
Sphingolipid signaling pathway
,
Oocyte meiosis
,
Cellular senescence
,
Adrenergic signaling in cardiomyocytes
,
VEGF signaling pathway
,
Osteoclast differentiation
,
Signaling pathways regulating pluripotency of stem cells
,
Platelet activation
,
Neutrophil extracellular trap formation
,
Toll-like receptor signaling pathway
,
NOD-like receptor signaling pathway
,
RIG-I-like receptor signaling pathway
,
C-type lectin receptor signaling pathway
,
IL-17 signaling pathway
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
T cell receptor signaling pathway
,
Fc epsilon RI signaling pathway
,
TNF signaling pathway
,
Leukocyte transendothelial migration
,
Thermogenesis
,
Neurotrophin signaling pathway
,
Retrograde endocannabinoid signaling
,
Dopaminergic synapse
,
Inflammatory mediator regulation of TRP channels
,
GnRH signaling pathway
,
Progesterone-mediated oocyte maturation
,
Prolactin signaling pathway
,
Relaxin signaling pathway
,
Non-alcoholic fatty liver disease
,
AGE-RAGE signaling pathway in diabetic complications
,
Growth hormone synthesis, secretion and action
,
Alcoholic liver disease
,
Amyotrophic lateral sclerosis
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Epithelial cell signaling in Helicobacter pylori infection
,
Pathogenic Escherichia coli infection
,
Shigellosis
,
Salmonella infection
,
Pertussis
,
Yersinia infection
,
Leishmaniasis
,
Chagas disease
,
Toxoplasmosis
,
Tuberculosis
,
Hepatitis B
,
Human cytomegalovirus infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Epstein-Barr virus infection
,
Human immunodeficiency virus 1 infection
,
Coronavirus disease - COVID-19
,
Proteoglycans in cancer
,
Chemical carcinogenesis - reactive oxygen species
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
Diabetic cardiomyopathy
,
Lipid and atherosclerosis
,
Fluid shear stress and atherosclerosis
62件:
Endocrine resistance
,
MAPK signaling pathway
,
Rap1 signaling pathway
,
FoxO signaling pathway
,
S
...
Neflamapimod
Neflamapimod
💬
2. MAPK14
×
Name
Other Names
Neflamapimod
Neflamapimod (USAN)
ネフラマピモド
Neflamapimod
1件:
8
8
💬
2. MAPK14
×
告示番号
日本語名
英語名
8
ハンチントン病
Huntington disease
3
F2
💬
3. F2
×
Name
Full Name
F2
coagulation factor II, thrombin
8件:
Phospholipase D signaling pathway
Phospholipase D signaling pathway
,
Neuroactive ligand-receptor interaction
,
Complement and coagulation cascades
,
Platelet activation
,
Regulation of actin cytoskeleton
,
Pathogenic Escherichia coli infection
,
Coronavirus disease - COVID-19
,
Pathways in cancer
8件:
Phospholipase D signaling pathway
,
Neuroactive ligand-receptor interaction
,
Complement and coagu
...
Thrombomodulin alfa
Thrombomodulin alfa
💬
3. F2
×
Name
Other Names
Thrombomodulin alfa
Thrombomodulin alfa (USAN/INN)
Thrombomodulin alfa (genetical recombination) (JAN)
トロンボモデュリン アルファ
リコモジュリン
Thrombomodulin Alfa
1件:
85
85
💬
3. F2
×
告示番号
日本語名
英語名
85
特発性間質性肺炎
Idiopathic interstitial pneumonia
4
F2
💬
4. F2
×
Name
Full Name
F2
coagulation factor II, thrombin
8件:
Phospholipase D signaling pathway
Phospholipase D signaling pathway
,
Neuroactive ligand-receptor interaction
,
Complement and coagulation cascades
,
Platelet activation
,
Regulation of actin cytoskeleton
,
Pathogenic Escherichia coli infection
,
Coronavirus disease - COVID-19
,
Pathways in cancer
8件:
Phospholipase D signaling pathway
,
Neuroactive ligand-receptor interaction
,
Complement and coagu
...
Dabigatran etexilate
Dabigatran etexilate
💬
4. F2
×
Name
Other Names
Dabigatran etexilate
Dabigatran etexilate (USAN/INN)
Pradaxa (TN)
ダビガトランエテキシラート
Dabigatran etexilate
2件:
51
51
,
75
💬
4. F2
×
告示番号
日本語名
英語名
51
全身性強皮症
Scleroderma
75
クッシング病
Cushing disease
5
F2
💬
5. F2
×
Name
Full Name
F2
coagulation factor II, thrombin
8件:
Phospholipase D signaling pathway
Phospholipase D signaling pathway
,
Neuroactive ligand-receptor interaction
,
Complement and coagulation cascades
,
Platelet activation
,
Regulation of actin cytoskeleton
,
Pathogenic Escherichia coli infection
,
Coronavirus disease - COVID-19
,
Pathways in cancer
8件:
Phospholipase D signaling pathway
,
Neuroactive ligand-receptor interaction
,
Complement and coagu
...
Dabigatran
Dabigatran
💬
5. F2
×
Name
Other Names
Dabigatran
Dabigatran (USAN/INN)
ダビガトラン
Dabigatran
5件:
51
51
,
75
,
85
,
91
,
124
💬
5. F2
×
告示番号
日本語名
英語名
51
全身性強皮症
Scleroderma
75
クッシング病
Cushing disease
85
特発性間質性肺炎
Idiopathic interstitial pneumonia
91
バッド・キアリ症候群
Budd-Chiari syndrome
124
皮質下梗塞と白質脳症を伴う常染色体優性脳動脈症
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy
6
FYN
💬
6. FYN
×
Name
Full Name
FYN
FYN proto-oncogene, Src family tyrosine kinase
14件:
Sphingolipid signaling pathway
Sphingolipid signaling pathway
,
Phospholipase D signaling pathway
,
Axon guidance
,
Osteoclast differentiation
,
Focal adhesion
,
Adherens junction
,
Platelet activation
,
Natural killer cell mediated cytotoxicity
,
T cell receptor signaling pathway
,
Fc epsilon RI signaling pathway
,
Cholinergic synapse
,
Prion disease
,
Pathogenic Escherichia coli infection
,
Viral myocarditis
14件:
Sphingolipid signaling pathway
,
Phospholipase D signaling pathway
,
Axon guidance
,
Osteoclast di
...
Dasatinib
Dasatinib
💬
6. FYN
×
Name
Other Names
Dasatinib
Dasatinib (JAN/INN)
ダサチニブ
Dasatinib
2件:
51
51
,
85
💬
6. FYN
×
告示番号
日本語名
英語名
51
全身性強皮症
Scleroderma
85
特発性間質性肺炎
Idiopathic interstitial pneumonia
7
FYN
💬
7. FYN
×
Name
Full Name
FYN
FYN proto-oncogene, Src family tyrosine kinase
14件:
Sphingolipid signaling pathway
Sphingolipid signaling pathway
,
Phospholipase D signaling pathway
,
Axon guidance
,
Osteoclast differentiation
,
Focal adhesion
,
Adherens junction
,
Platelet activation
,
Natural killer cell mediated cytotoxicity
,
T cell receptor signaling pathway
,
Fc epsilon RI signaling pathway
,
Cholinergic synapse
,
Prion disease
,
Pathogenic Escherichia coli infection
,
Viral myocarditis
14件:
Sphingolipid signaling pathway
,
Phospholipase D signaling pathway
,
Axon guidance
,
Osteoclast di
...
Dasatinib
Dasatinib
💬
7. FYN
×
Name
Other Names
Dasatinib
Dasatinib (USAN)
Dasatinib hydrate (JAN)
Sprycel (TN)
ダサチニブ水和物
スプリセル
Dasatinib
2件:
51
51
,
85
💬
7. FYN
×
告示番号
日本語名
英語名
51
全身性強皮症
Scleroderma
85
特発性間質性肺炎
Idiopathic interstitial pneumonia
8
GUCY1A2
💬
8. GUCY1A2
×
Name
Full Name
GUCY1A2
guanylate cyclase 1 soluble subunit alpha 2
11件:
Purine metabolism
Purine metabolism
,
Metabolic pathways
,
cGMP-PKG signaling pathway
,
Vascular smooth muscle contraction
,
Gap junction
,
Platelet activation
,
Circadian entrainment
,
Long-term depression
,
Oxytocin signaling pathway
,
Renin secretion
,
Salivary secretion
11件:
Purine metabolism
,
Metabolic pathways
,
cGMP-PKG signaling pathway
,
Vascular smooth muscle contr
...
Amyl nitrite
Amyl nitrite
💬
8. GUCY1A2
×
Name
Other Names
Amyl nitrite
Amyl nitrite (JP18/USP)
Aspiral (TN)
Vaporole (TN)
亜硝酸アミル
Amyl Nitrite
1件:
58
58
💬
8. GUCY1A2
×
告示番号
日本語名
英語名
58
肥大型心筋症
Hypertrophic cardiomyopathy
9
GUCY1A2
💬
9. GUCY1A2
×
Name
Full Name
GUCY1A2
guanylate cyclase 1 soluble subunit alpha 2
11件:
Purine metabolism
Purine metabolism
,
Metabolic pathways
,
cGMP-PKG signaling pathway
,
Vascular smooth muscle contraction
,
Gap junction
,
Platelet activation
,
Circadian entrainment
,
Long-term depression
,
Oxytocin signaling pathway
,
Renin secretion
,
Salivary secretion
11件:
Purine metabolism
,
Metabolic pathways
,
cGMP-PKG signaling pathway
,
Vascular smooth muscle contr
...
Riociguat
Riociguat
💬
9. GUCY1A2
×
Name
Other Names
Riociguat
Riociguat (JAN/USAN/INN)
Adempas (TN)
リオシグアト
アデムパス
Riociguat
6件:
51
51
,
84
,
86
,
88
,
225
,
299
💬
9. GUCY1A2
×
告示番号
日本語名
英語名
51
全身性強皮症
Scleroderma
84
サルコイドーシス
Sarcoidosis
86
肺動脈性肺高血圧症
Pulmonary arterial hypertension
88
慢性血栓塞栓性肺高血圧症;特発性慢性肺血栓塞栓症（肺高血圧型）
Chronic thromboembolic pulmonary hypertension
225
先天性腎性尿崩症;遺伝性腎性尿崩症
Congenital nephrogenic diabetes insipidus
299
嚢胞性線維症;膵囊胞線維症
Cystic fibrosis
10
GUCY1A1
💬
10. GUCY1A1
×
Name
Full Name
GUCY1A1
guanylate cyclase 1 soluble subunit alpha 1
11件:
Purine metabolism
Purine metabolism
,
Metabolic pathways
,
cGMP-PKG signaling pathway
,
Vascular smooth muscle contraction
,
Gap junction
,
Platelet activation
,
Circadian entrainment
,
Long-term depression
,
Oxytocin signaling pathway
,
Renin secretion
,
Salivary secretion
11件:
Purine metabolism
,
Metabolic pathways
,
cGMP-PKG signaling pathway
,
Vascular smooth muscle contr
...
Amyl nitrite
Amyl nitrite
💬
10. GUCY1A1
×
Name
Other Names
Amyl nitrite
Amyl nitrite (JP18/USP)
Aspiral (TN)
Vaporole (TN)
亜硝酸アミル
Amyl Nitrite
1件:
58
58
💬
10. GUCY1A1
×
告示番号
日本語名
英語名
58
肥大型心筋症
Hypertrophic cardiomyopathy