Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank 薬物名（臨床試験情報から抽出） KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Water 1件: Water8件: AVONEX; ENBREL; Hiberix; Indocyanine green; OMNITROPE; Sterile Water for Injection; Water; WATER FOR INJECTION; --21件: 2, 5, 6, 13, 17, 22, 35, 46, 53, 57, 63, 65, 67, 78, 84, 96, 97, 206, 226, 278, 299
2 Oxygen 1件: Oxygen3件: Medical air; Nitrogen; Oxygen; --13件: 6, 49, 70, 85, 86, 88, 90, 96, 168, 193, 271, 299, 330
3 Alanine 1件: Alanine2件: Alanine; L-alanine; --4件: 6, 13, 298, 299
4 Glutathione 1件: Glutathione2件: GLUTATHIONE; Reduced glutathione; --2件: 6, 299
5 Serine 1件: Serine2件: L-Serine; Serine; --4件: 2, 6, 86, 96
6 Tryptophan 1件: Tryptophan2件: Propanoic acid; Tryptophan; --2件: 6, 75
7 Tyrosine 1件: Tyrosine4件: Alanine; L-Tyrosine; Propanoic acid; Tyrosine; --5件: 6, 75, 86, 111, 298
8 Glycerin 1件: Glycerin2件: Bee venom; Glycerol; --5件: 6, 13, 79, 316, 317
9 Leucine 1件: Leucine2件: L-leucine; Leucine; --6件: 6, 19, 65, 283, 284, 299
10 Oxiglutatione 1件: Glutathione2件: GLUTATHIONE; Reduced glutathione; --2件: 6, 299
11 Niacinamide 1件: Nicotinamide3件: Multivitamin; Niacinamide; Nicotinamide; --10件: 2, 5, 6, 18, 49, 67, 97, 107, 162, 191
12 Anhydrous lactose 1件: Lactose1件: Lactose; --6件: 2, 6, 13, 97, 228, 310
13 Niacin 1件: Niacin2件: Niacin; Nicotinic acid; --3件: 6, 78, 79
14 Inosine 1件: Inosine1件: Inosine; --6件: 2, 6, 13, 17, 85, 122
15 Citicoline 1件: Citicoline1件: Citicolina; --1件: 6
16 Levodopa 1件: Levodopa9件: Carbidopa-Levodopa; DUODOPA; Inbrija; L-DOPA; Levodopa; PARCOPA; SINEMET; SINEMET CR; Stalevo; 5件: DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		11件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬6件: 6, 17, 90, 140, 164, 201
17 Mannitol 1件: Mannitol4件: Aridol; Bronchitol; Mannite; Mannitol; --7件: 6, 13, 28, 60, 96, 113, 299
18 Folic acid 1件: Folic acid5件: Acide folique; Folate; Folic acid; Multivitamin; NICOTINAMIDE; --6件: 6, 41, 46, 49, 84, 296
19 Nitric oxide 1件: Nitric Oxide3件: INOmax; Nitric Oxide; Nitrosyl; --12件: 6, 58, 85, 86, 88, 97, 210, 222, 251, 294, 299, 321
20 Nitrogen 1件: Nitrogen1件: Nitrogen; --5件: 5, 6, 17, 211, 299
21 Hydrocortisone 1件: Hydrocortisone6件: Cortef; Cortisol; Cortisone; Hydrocortisone; Hydrocortisone cream; Hydrocortisonum; 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬10件: 6, 41, 46, 53, 75, 78, 81, 83, 97, 299
22 Oxytocin 1件: Oxytocin2件: Oxytocin; Syntocinon; 1件: OXTR 💬4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬7件: 6, 72, 127, 168, 193, 206, 226
23 Tacrolimus 1件: Tacrolimus2件: Prograf; Tacrolimus; 5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬34件: 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
24 Albendazole 1件: Albendazole2件: Albendazole; Eskazole; --12件: 5, 6, 7, 13, 28, 51, 67, 86, 96, 97, 114, 127
25 Erythromycin 1件: Erythromycin1件: Erythromycin; --5件: 6, 36, 164, 228, 291
26 Cyanocobalamin 1件: Cyanocobalamin2件: Cianocobalamina; Vitamin B12; --5件: 6, 13, 201, 229, 299
27 Inulin 1件: Inulin1件: Inulin; --4件: 6, 96, 156, 299
28 Cholecalciferol 1件: Cholecalciferol5件: Cholecalciferol; COLECALCIFEROL; Multivitamin; Vitamin D; Vitamin D3; 1件: VDR 💬5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬24件: 6, 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299
29 Ampicillin 1件: Ampicillin1件: ABPC; --5件: 2, 6, 13, 84, 299
30 Rifampin 1件: Rifampicin2件: Rifampicin; Rifampin; --9件: 6, 13, 17, 46, 84, 86, 93, 299, 338
31 Acetaminophen 1件: Acetaminophen4件: Acetaminophen; Paracetamol; Tylenol; Ultracet; 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬15件: 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337
32 Acetylcysteine 1件: Acetylcysteine3件: Acetylcysteine; Mucomyst; N-Acetylcysteine; --21件: 6, 13, 19, 20, 21, 49, 51, 53, 58, 63, 85, 90, 94, 111, 164, 193, 233, 296, 298, 299, 337
33 Allopurinol 1件: Allopurinol2件: Allopurinol; ALLOPURINOL SODIUM; 1件: XDH 💬6件: Caffeine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Peroxisome, Purine metabolism 💬7件: 6, 46, 57, 60, 66, 96, 97
34 Amoxicillin 1件: Amoxicillin4件: Amoxicilina; AMOXICILLIN; Amoxycillin; Augmentin; --9件: 6, 19, 46, 63, 84, 96, 97, 222, 299
35 Azathioprine 1件: Azathioprine3件: AZATHIOPRINE; Azatioprina; Imuran; --21件: 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 63, 65, 66, 85, 93, 94, 95, 96, 97, 162
36 Bumetanide 1件: Bumetanide1件: Bumetanide; 1件: SLC12A2 💬3件: Pancreatic secretion, Salivary secretion, Vibrio cholerae infection 💬2件: 6, 158
37 Capsaicin 1件: Capsaicin2件: Capsaicin; Qutenza; 1件: TRPV1 💬2件: Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬3件: 6, 86, 226
38 Captopril 1件: Captopril1件: Captopril; 1件: ACE 💬6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬8件: 6, 17, 46, 86, 96, 97, 107, 271
39 Carbamazepine 1件: Carbamazepine1件: Carbamazepine; 5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬3件: 6, 13, 231
40 Clarithromycin 1件: Clarithromycin1件: Clarithromycin; --8件: 6, 63, 84, 96, 97, 222, 228, 299
41 Clonazepam 1件: Clonazepam1件: Clonazepam; 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬1件: 6
42 Clonidine 1件: Clonidine4件: Clonidin; Clonidina; Clonidine; CLONIDINE HYDROCHLORIDE; 3件: ADRA2A,
ADRA2B,
ADRA2C 💬		2件: Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬4件: 6, 65, 70, 78
43 Clozapine 1件: Clozapine1件: CLOZAPINE; 11件: ADRA2A,
ADRA2B,
ADRA2C,
DRD4,
HTR2A,
HTR2C,
HTR3A,
HTR3B,
HTR3C,
HTR3D,
HTR3E 💬		8件: Calcium signaling pathway, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction, cGMP-PKG signaling pathway 💬1件: 6
44 Desmopressin 1件: Desmopressin5件: DDAVP; Desmopressin; Desmopressin Acetate; Desmopressine; Minirin; 2件: AVPR2,
F8 💬		4件: Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬6件: 6, 64, 72, 75, 225, 288
45 Dihydrotachysterol 1件: Dihydrotachysterol0件: 1件: VDR 💬5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬2件: 6, 85
46 Famotidine 1件: Famotidine2件: FAMOTIDINA; Famotidine; 1件: HRH2 💬3件: Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬6件: 6, 46, 61, 86, 98, 107
47 Finasteride 1件: Finasteride1件: Finasteride; 1件: SRD5A2 💬3件: Metabolic pathways, Prostate cancer, Steroid hormone biosynthesis 💬1件: 6
48 Furosemide 1件: Furosemide2件: Furosemide; Furosemide Injection; 1件: SLC12A2 💬3件: Pancreatic secretion, Salivary secretion, Vibrio cholerae infection 💬2件: 6, 86
49 Gabapentin 1件: Gabapentin4件: Gabapentin; GABAPENTINA; Gabapentine; NEURONTIN; 5件: CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4,
SLC6A1 💬		9件: Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway, Synaptic vesicle cycle 💬5件: 6, 13, 19, 70, 298
50 Isradipine 1件: Isradipine1件: Isradipine; 4件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 6
51 Lidocaine 1件: Lidocaine4件: Aloe; Lidocaine; Lignocaine; Xylocaine; 5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬13件: 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256
52 Lovastatin 1件: Lovastatin1件: Lovastatin; 1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬11件: 6, 34, 46, 79, 156, 160, 195, 206, 263, 280, 310
53 Tropicamide 1件: Tropicamide1件: Tropicamide; 5件: CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		13件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬1件: 6
54 Valproic acid 1件: Valproic acid3件: Valproate; VALPROATE SODIUM; Valproic Acid; 7件: ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
GAD1,
GAD2 💬		17件: Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬14件: 2, 3, 5, 6, 13, 26, 65, 85, 90, 102, 127, 222, 233, 256
55 Zolmitriptan 1件: Zolmitriptan1件: Zolmitriptan; 2件: HTR1B,
HTR1D 💬		4件: Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬1件: 6
56 Nadolol 1件: Nadolol1件: Nadolol; 2件: ADRB1,
ADRB2 💬		11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 6
57 Simvastatin 1件: Simvastatin3件: Simvastatin; Simvastatina; Simvastatine; 1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬21件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310
58 Omeprazole 1件: Omeprazole4件: Losec; Omeprazol; Omeprazole; OMEPRAZOLE MAGNESIUM; 2件: ATP4A,
ATP4B 💬		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬14件: 6, 8, 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299
59 Ondansetron 1件: Ondansetron1件: Ondansetron; 5件: HTR3A,
HTR3B,
HTR3C,
HTR3D,
HTR3E 💬		2件: Serotonergic synapse, Taste transduction 💬3件: 6, 97, 107
60 Oxybutynin 1件: Oxybutynin1件: Oxybutynin; 5件: CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		13件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬3件: 6, 13, 53
61 Pyrimethamine 1件: Pyrimethamine2件: Daraprim; PYRIMETHAMINE; --12件: 2, 4, 6, 13, 19, 46, 51, 63, 65, 96, 97, 265
62 Dexmedetomidine 1件: Dexmedetomidine4件: Dexdor; DEXMEDETOMIDINA; Dexmedetomidine; DEXMEDETOMIDINE HYDROCHLORIDE; 3件: ADRA2A,
ADRA2B,
ADRA2C 💬		2件: Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬14件: 2, 4, 6, 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280
63 Pilocarpine 1件: Pilocarpine2件: Pilocarpine; Pilocarpine Hydrochloride; 2件: CHRM2,
CHRM3 💬		13件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬3件: 6, 53, 299
64 Caffeine 1件: Caffeine1件: Caffeine; 11件: ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬		22件: Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬8件: 2, 6, 21, 46, 78, 96, 97, 265
65 Topiramate 1件: Topiramate2件: TOPAMAX; Topiramate; 36件: CA2,
CA4,
CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S,
GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ,
GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		53件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Arrhythmogenic right ventricular cardiomyopathy, Bile secretion, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Collecting duct acid secretion, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Huntington disease, Hypertrophic cardiomyopathy, Insulin secretion, Long-term depression, Long-term potentiation, MAPK signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Nitrogen metabolism, Oxytocin signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Prion disease, Proximal tubule bicarbonate reclamation, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Tight junction, Transcriptional misregulation in cancer, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬6件: 6, 97, 140, 144, 156, 193
66 Zonisamide 1件: Zonisamide2件: Zonegran; Zonisamide; 8件: CACNA1G,
CACNA1H,
CACNA1I,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		11件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dopaminergic synapse, GnRH secretion, MAPK signaling pathway, Taste transduction, Type II diabetes mellitus 💬1件: 6
67 Isoflurane 1件: Isoflurane1件: Isoflurane; --1件: 6
68 Sevoflurane 1件: Sevoflurane1件: Sevoflurane; --7件: 6, 21, 22, 34, 98, 225, 296
69 Etomidate 1件: Etomidate1件: Etomidate; 1件: GABRA1 💬6件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Taste transduction 💬1件: 6
70 Propofol 1件: Propofol2件: Propofol; Propofol Injection; 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬9件: 6, 21, 22, 34, 46, 70, 75, 98, 296
71 Midazolam 1件: Midazolam2件: Midazolam; Midazolam injection; 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬12件: 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299
72 Carbidopa 1件: Carbidopa8件: Carbidopa; Carbidopa-Levodopa; DUODOPA; Lodosyn; PARCOPA; SINEMET; SINEMET CR; Stalevo; 1件: DDC 💬9件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Metabolic pathways, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬7件: 6, 13, 17, 90, 140, 164, 201
73 Repaglinide 1件: Repaglinide1件: Repaglinide; 2件: ABCC8,
KCNJ11 💬		4件: ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬4件: 6, 21, 46, 299
74 Flumazenil 1件: Flumazenil1件: Flumazenil; 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬5件: 6, 13, 17, 18, 206
75 Levetiracetam 1件: Levetiracetam2件: KEPPRA; Levetiracetam; 1件: SV2A 💬1件: ECM-receptor interaction 💬5件: 2, 4, 6, 13, 307
76 Ursodiol 1件: Ursodeoxycholic acid4件: UDCA; URSODEOXYCHOLIC ACID; Ursodiol; UrsoFalk; 1件: NR1H4 💬1件: Bile secretion 💬14件: 6, 8, 20, 46, 67, 84, 93, 94, 95, 96, 97, 234, 296, 299
77 Entacapone 1件: Entacapone5件: COMTAN; Comtess; ENTACAPONA; ENTACAPONE; Stalevo; 1件: COMT 💬4件: Dopaminergic synapse, Metabolic pathways, Steroid hormone biosynthesis, Tyrosine metabolism 💬2件: 6, 17
78 Botulinum toxin type A 1件: Botulinum toxin type A8件: Botox; Botulinum toxin A; BOTULINUM TOXIN TYPE A; BTX-A; Dysport; IncobotulinumtoxinA; OnabotulinumtoxinA; Xeomin; 1件: SNAP25 💬2件: Insulin secretion, Synaptic vesicle cycle 💬14件: 2, 5, 6, 7, 13, 15, 17, 36, 47, 51, 70, 113, 149, 226
79 Tolcapone 1件: Tolcapone3件: Tasmar; Tolcapon; TOLCAPONE; 1件: COMT 💬4件: Dopaminergic synapse, Metabolic pathways, Steroid hormone biosynthesis, Tyrosine metabolism 💬3件: 6, 28, 127
80 Hydrocortisone cypionate 1件: Hydrocortisone cypionate1件: Cortef; 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬3件: 6, 81, 83
81 Cabergoline 1件: Cabergoline3件: CABERGOLINA; Cabergoline; DOSTINEX; 2件: DRD2,
PRL 💬		12件: Alcoholism, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway 💬3件: 6, 74, 75
82 Ubidecarenone 1件: Ubidecarenone3件: Coenzyme Q-10; Coenzyme Q10; CoQ10; --12件: 2, 5, 6, 8, 10, 18, 46, 57, 86, 113, 214, 215
83 Exametazime 1件: Exametazime1件: Exametazime; --1件: 6
84 Aripiprazole 1件: Aripiprazole1件: Aripiprazole; 4件: DRD2,
DRD3,
HTR1A,
HTR2A 💬		12件: Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬2件: 6, 206
85 Magnesium oxide 1件: Magnesium oxide1件: Magnesium oxide; --3件: 6, 166, 291
86 Febuxostat 1件: Febuxostat1件: Febuxostat; 1件: XDH 💬6件: Caffeine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Peroxisome, Purine metabolism 💬3件: 2, 6, 13
87 Sulpiride 1件: Sulpiride0件: 1件: DRD2 💬8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬2件: 6, 70
88 Josamycin 1件: Josamycin0件: --2件: 6, 13
89 Droxidopa 1件: Droxidopa4件: DOPS; Droxidopa; L-DOPS; Northera; 9件: ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		14件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬5件: 5, 6, 17, 169, 170
90 Zopiclone 1件: Zopiclone1件: Zopiclone; 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬1件: 6
91 Hydrocortisone succinate 1件: Hydrocortisone succinate2件: HYDROCORTISONE HYDROGEN SUCCINATE; Solu-Cortef; 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬3件: 6, 81, 83
92 Caffeine hydrate 1件: Caffeine1件: Caffeine; 11件: ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬		22件: Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬8件: 2, 6, 21, 46, 78, 96, 97, 265
93 Edaravone 1件: Edaravone3件: Edaravone; Methylphenylpyrazolone; Norphenazone; --3件: 2, 6, 22
94 Domperidone 1件: Domperidone1件: Domperidone; 1件: DRD2 💬8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬5件: 6, 13, 17, 51, 230
95 Idebenone 1件: Idebenone2件: Idebenone; Raxone; --6件: 6, 8, 13, 18, 113, 302
96 Modafinil 1件: Modafinil2件: MODAFINIL; Provigil; --5件: 6, 13, 49, 93, 113
97 Silodosin 1件: Silodosin2件: Silodosin; Silodyx; 1件: ADRA1A 💬7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬2件: 6, 13
98 Zoledronic acid 1件: Zoledronic acid4件: ACLASTA; Zoledronate; Zoledronic Acid; Zometa; 1件: FDPS 💬4件: Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬13件: 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333
99 Tadalafil 1件: Tadalafil4件: Adcirca; Cialis; Tadalafil; TADALAFILO; 1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬7件: 6, 51, 75, 84, 86, 113, 210
100 Potassium carbonate 1件: Potassium carbonate0件: --3件: 6, 96, 291
101 Sodium chloride 1件: Sodium chloride6件: Lactated Ringers; Natriumchlorid; REBIF; Saline; Sodium chloride; Sporanox; --20件: 6, 11, 13, 14, 34, 41, 46, 50, 51, 53, 60, 67, 70, 96, 168, 193, 227, 228, 288, 299
102 Tulobuterol 1件: Tulobuterol1件: Tulobuterol; 1件: ADRB2 💬9件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 6
103 Maltodextrin 1件: Maltodextrin1件: Maltodextrin; --4件: 6, 13, 96, 97
104 Vitamin E 1件: Vitamin E2件: Alpha-tocopherol; Vitamin E; --12件: 2, 6, 13, 20, 46, 49, 90, 96, 97, 206, 299, 317
105 Dipivefrin 1件: Dipivefrin2件: Dipivefrin; Dipivefrine; 9件: ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		14件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 6
106 Sertraline 1件: Sertraline1件: Sertraline; 1件: SLC6A4 💬2件: Serotonergic synapse, Synaptic vesicle cycle 💬2件: 6, 206
107 Paroxetine 1件: Paroxetine1件: Paroxetine; 1件: SLC6A4 💬2件: Serotonergic synapse, Synaptic vesicle cycle 💬4件: 6, 13, 46, 85
108 Aspartame 1件: Aspartame0件: 2件: TAS1R2,
TAS1R3 💬		2件: Carbohydrate digestion and absorption, Taste transduction 💬4件: 6, 13, 67, 86
109 Rifaximin 1件: Rifaximin3件: Rifaximin; RIFAXIMINA; Xifaxan; --9件: 6, 65, 93, 94, 96, 97, 99, 296, 299
110 Moclobemide 1件: Moclobemide1件: MOCLOBEMIDE; 1件: MAOA 💬14件: Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬1件: 6
111 Agomelatine 1件: Agomelatine1件: Agomelatine; 3件: HTR2C,
MTNR1A,
MTNR1B 💬		6件: Calcium signaling pathway, Circadian entrainment, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse 💬1件: 6
112 Iproniazid 1件: Iproniazid1件: IPRONIAZID; 2件: MAOA,
MAOB 💬		14件: Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬1件: 6
113 Eszopiclone 1件: Eszopiclone2件: Eszopiclone; Zopiclone; 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬3件: 6, 13, 46
114 Iloperidone 1件: Iloperidone1件: Iloperidone; 4件: DRD2,
HTR2A,
HTR2B,
HTR2C 💬		11件: Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬1件: 6
115 Ramelteon 1件: Ramelteon2件: Ramelteon; ROZEREM; 2件: MTNR1A,
MTNR1B 💬		2件: Circadian entrainment, Neuroactive ligand-receptor interaction 💬3件: 6, 8, 46
116 Talampanel 1件: Talampanel1件: Talampanel; 4件: GRIA1,
GRIA2,
GRIA3,
GRIA4 💬		16件: Amphetamine addiction, Amyotrophic lateral sclerosis, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Transcriptional misregulation in cancer, cAMP signaling pathway 💬2件: 2, 6
117 Rimabotulinumtoxin B 1件: Botulinum toxin type B3件: Botulinum toxin type B; MYOBLOC; NEUROBLOC; 1件: SNAP25 💬2件: Insulin secretion, Synaptic vesicle cycle 💬4件: 2, 6, 13, 51
118 Ammonia solution, strong 1件: Ammonia1件: Ammonia; --2件: 6, 296
119 Benserazide 1件: Benserazide1件: BENSERAZIDE; 1件: DDC 💬9件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Metabolic pathways, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬1件: 6
120 Bromocriptine 1件: Bromocriptine1件: BROMOCRIPTINE; 2件: DRD2,
PRL 💬		12件: Alcoholism, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway 💬2件: 6, 74
121 Armodafinil 1件: Armodafinil2件: Armodafinil; Modafinil; 1件: SLC6A3 💬7件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬3件: 6, 13, 84
122 Lactose 1件: Lactose1件: Lactose; --6件: 2, 6, 13, 97, 228, 310
123 Filgrastim 1件: Filgrastim7件: FILGRASTIM; Filgrastim Hexal; G-CSF; Granulocyte Colony Stimulating Factor; Neupogen; TEVAGRASTIM; Zarzio; 1件: CSF3R 💬5件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬35件: 2, 6, 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331
124 Nicotine 1件: Nicotine2件: NICOTINE; Nicotine gum; 16件: CHRNA1,
CHRNA10,
CHRNA2,
CHRNA3,
CHRNA4,
CHRNA5,
CHRNA6,
CHRNA7,
CHRNA9,
CHRNB1,
CHRNB2,
CHRNB3,
CHRNB4,
CHRND,
CHRNE,
CHRNG 💬		8件: Alzheimer disease, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Virion - Lyssavirus 💬3件: 6, 13, 84
125 Polyethylene glycol 3350 1件: Polyethylene glycol4件: Macrogol; Macrogol 4000; Polyethylene glycol; Polyethylene Glycol 3350; --17件: 6, 13, 41, 46, 60, 65, 78, 96, 97, 140, 144, 235, 240, 246, 276, 299, 337
126 Cyanocobalamin Co 57 1件: Cyanocobalamin2件: Cianocobalamina; Vitamin B12; --5件: 6, 13, 201, 229, 299
127 Cyanocobalamin Co 58 1件: Cyanocobalamin2件: Cianocobalamina; Vitamin B12; --5件: 6, 13, 201, 229, 299
128 Cyanocobalamin Co 60 1件: Cyanocobalamin2件: Cianocobalamina; Vitamin B12; --5件: 6, 13, 201, 229, 299
129 Darifenacin 1件: Darifenacin2件: Darifenacin; Emselex; 1件: CHRM3 💬11件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬2件: 6, 13
130 Selegiline 1件: Selegiline2件: SELEGILINE; Zelapar; 1件: MAOB 💬14件: Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬1件: 6
131 Dextromethorphan 1件: Dextromethorphan4件: Dextromethorphan; Dextromethorphan hydrobromide; Dextrometorfano; Nuedexta; 6件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
132 Rivastigmine 1件: Rivastigmine3件: Exelon; Rivastigmine; Rivastigmine Transdermal System; 1件: ACHE 💬2件: Cholinergic synapse, Glycerophospholipid metabolism 💬3件: 5, 6, 13
133 Exenatide 1件: Exenatide3件: Bydureon; Byetta; Exenatide; 1件: GLP1R 💬3件: Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬6件: 6, 17, 72, 78, 193, 233
134 Dalfampridine 1件: Dalfampridine7件: 4-Aminopyridine; 4-AP; AMPYRA; Dalfampridine; FAMPRIDINA; FAMPRIDINE; Fampyra; 4件: KCNA4,
KCNC3,
KCND2,
KCND3 💬		4件: Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬5件: 3, 4, 6, 13, 14
135 Galantamine 1件: Galantamine2件: GALANTAMINE; Galantamine hydrobromide; 1件: ACHE 💬2件: Cholinergic synapse, Glycerophospholipid metabolism 💬2件: 6, 127
136 Lactomin 1件: Lactobacillus acidophilus4件: Acidophilus; Lacteol; Lactobacillus; Lactobacillus acidophilus; --3件: 6, 49, 97
137 Lactobacillus casei 1件: Lactobacillus casei2件: Fusion; Lactobacillus casei; --10件: 6, 11, 13, 46, 49, 69, 70, 97, 271, 296
138 Guar gum 1件: Guar gum1件: Guar gum; --1件: 6
139 Istradefylline 1件: Istradefylline1件: ISTRADEFYLLINE; 1件: ADORA2A 💬7件: Alcoholism, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway 💬1件: 6
140 Liatermin 1件: Liatermin2件: Liatermin; R-metHuGDNF; --1件: 6
141 Lithium citrate 1件: Lithium citrate2件: Lithium; LITHIUM CITRATE; --5件: 2, 5, 6, 7, 8
142 Lubiprostone 1件: Lubiprostone1件: LUBIPROSTONE; 1件: CLCN2 💬1件: Mineral absorption 💬4件: 6, 13, 290, 299
143 Metformin 1件: Metformin5件: Metformin; Metformin HCl; Metformin hydrochloride; Metformina; Metformine; 2件: PRKAA1,
PRKAA2 💬		20件: AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬25件: 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301
144 Methylphenidate 1件: Methylphenidate3件: Methylphenidate; METHYLPHENIDATE HYDROCHLORIDE; Ritalin; 2件: SLC6A2,
SLC6A3 💬		7件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬7件: 6, 13, 34, 84, 113, 179, 206
145 Minocycline 1件: Minocycline3件: Minocycline; Minocycline hydrochloride; Minomycin; --14件: 2, 6, 8, 13, 46, 84, 85, 90, 94, 162, 201, 206, 280, 299
146 Nabilone 1件: Nabilone1件: NABILONE; 2件: CNR1,
CNR2 💬		4件: Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬3件: 6, 13, 127
147 Nalmefene 1件: Nalmefene1件: Nalmefene; 3件: OPRD1,
OPRK1,
OPRM1 💬		5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬1件: 6
148 Naltrexone 1件: Naltrexone2件: Naltrexone; Naltrexone Hydrochloride; 3件: OPRD1,
OPRK1,
OPRM1 💬		5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬13件: 6, 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226
149 Nitisinone 1件: Nitisinone2件: NITISINONE; Orfadin; 1件: HPD 💬5件: Biosynthesis of cofactors, Metabolic pathways, Phenylalanine metabolism, Tyrosine metabolism, Ubiquinone and other terpenoid-quinone biosynthesis 💬3件: 6, 164, 241
150 Oxycodone 1件: Oxycodone2件: Oxycodone; OXYCODONE HYDROCHLORIDE; 3件: OPRD1,
OPRK1,
OPRM1 💬		5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬5件: 6, 13, 70, 226, 298
151 Plantago seed 1件: Plantago seed2件: Psyllium; Psyllium husk; --3件: 6, 28, 97
152 Pramipexole 1件: Pramipexole7件: Mirapex; Mirapex ER; Mirapexin; Pramipexol; Pramipexole; PRAMIPEXOLE DIHYDROCHLORIDE; SIFROL; 3件: DRD2,
DRD3,
DRD4 💬		8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬3件: 2, 6, 20
153 Rotigotine 1件: Rotigotine3件: NEUPRO; ROTIGOTINA; ROTIGOTINE; 1件: DRD2 💬8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6
154 Sargramostim 1件: Sargramostim2件: Leukine; Sargramostim; 1件: CSF2RA 💬4件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, Pathways in cancer 💬7件: 6, 28, 60, 62, 96, 229, 285
155 Sodium oxybate 1件: Sodium oxybate1件: Sodium Oxybate; --2件: 6, 149
156 Sulfachlorpyridazine 1件: Sulfachlorpyridazine0件: --1件: 6
157 Liraglutide 1件: Liraglutide2件: LIRAGLUTIDE; Saxenda; 1件: GLP1R 💬3件: Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬3件: 6, 75, 193
158 Wheat 1件: Wheat1件: Wheat; --2件: 6, 53
159 Green tea leaf 1件: Green tea leaf4件: Green Tea; Green Tea Extract; GREEN TEA LEAF; Tea Extract; --4件: 6, 17, 28, 46
160 Acamprosate 1件: Acamprosate1件: Acamprosate; 5件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬2件: 6, 206
161 Ademetionine 1件: Ademetionine2件: SAM-e; SAMe; --2件: 6, 93
162 Heptaminol 1件: Heptaminol1件: Heptaminol; --1件: 6
163 Fesoterodine 1件: Fesoterodine1件: Fesoterodine; 2件: CHRM2,
CHRM3 💬		13件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬1件: 6
164 Melevodopa 1件: Melevodopa1件: Melevodopa; --1件: 6
165 Piribedil 1件: Piribedil1件: Piribedil; 2件: DRD2,
DRD3 💬		8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6
166 Melperone 1件: Melperone1件: Melperone; 1件: DRD2 💬8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6
167 Deferiprone 1件: Deferiprone2件: Deferiprone; Ferriprox; --6件: 2, 6, 18, 120, 122, 233
168 Amantadine 1件: Amantadine3件: Amantadine; AMANTADINE HYDROCHLORIDE; GOCOVRI; 5件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬4件: 6, 8, 13, 127
169 Ambroxol 1件: Ambroxol1件: Ambroxol; --2件: 6, 19
170 Amoxicillin 1件: Amoxicillin4件: Amoxicilina; Amoxicillin; Amoxycillin; Augmentin; --9件: 6, 19, 46, 63, 84, 96, 97, 222, 299
171 Apomorphine 1件: Apomorphine4件: APOKYN; Apomorfina; Apomorphine; Apomorphine Hydrocloride; 2件: DRD1,
DRD2 💬		11件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬3件: 5, 6, 7
172 Atomoxetine 1件: Atomoxetine2件: Atomoxetine; Strattera; 1件: SLC6A2 💬1件: Synaptic vesicle cycle 💬4件: 6, 8, 13, 17
173 Buspirone 1件: Buspirone2件: Buspirone; Buspirone Hydrochloride; 2件: DRD2,
HTR1A 💬		10件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬2件: 6, 51
174 Ceftriaxone 1件: Ceftriaxone1件: Ceftriaxone; --4件: 2, 6, 46, 97
175 Citalopram 1件: Citalopram1件: Citalopram; 1件: SLC6A4 💬2件: Serotonergic synapse, Synaptic vesicle cycle 💬7件: 6, 8, 13, 18, 46, 98, 127
176 Clenbuterol 1件: Clenbuterol1件: Clenbuterol; 1件: ADRB2 💬9件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬5件: 1, 2, 6, 13, 256
177 Deanol 1件: Deanol1件: Deanol; --1件: 6
178 Delorazepam 1件: Delorazepam0件: 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬3件: 6, 46, 97
179 Dihydroergotoxine 1件: Dihydroergotoxine1件: Dihydroergotoxine; --1件: 6
180 Domperidone maleate 1件: Domperidone1件: Domperidone; 1件: DRD2 💬8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬5件: 6, 13, 17, 51, 230
181 Donepezil 1件: Donepezil3件: Aricept; Donepezil; Donepezil hydrochloride; 1件: ACHE 💬2件: Cholinergic synapse, Glycerophospholipid metabolism 💬9件: 5, 6, 13, 46, 78, 124, 127, 156, 206
182 Dopamine 1件: Dopamine2件: Dopamina; Dopamine; 5件: DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		11件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬4件: 6, 7, 74, 299
183 Doxepin 1件: Doxepin1件: Doxepin; 3件: HRH1,
SLC6A2,
SLC6A4 💬		5件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle 💬1件: 6
184 Duloxetine 1件: Duloxetine3件: CYMBALTA; Duloxetine; Duloxetine hydrochloride; 2件: SLC6A2,
SLC6A4 💬		2件: Serotonergic synapse, Synaptic vesicle cycle 💬2件: 6, 13
185 Escitalopram 1件: Escitalopram3件: Citalopram; Escitalopram; Escitalopram oxalate; 1件: SLC6A4 💬2件: Serotonergic synapse, Synaptic vesicle cycle 💬4件: 2, 6, 13, 46
186 Flecainide 1件: Flecainide3件: Flecainide; FLECAINIDE ACETATE; Flecainidum; 5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬1件: 6
187 Fludrocortisone 1件: Fludrocortisone1件: Fludrocortisone; 1件: NR3C2 💬1件: Aldosterone-regulated sodium reabsorption 💬3件: 6, 17, 81
188 Ketamine 1件: Ketamine2件: Ketamine; NMDA; 5件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬8件: 2, 4, 6, 13, 70, 113, 156, 215
189 Lidocaine hydrochloride monohydrate 1件: Lidocaine4件: Aloe; Lidocaine; Lignocaine; Xylocaine; 5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬13件: 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256
190 Lisuride 1件: Lisuride1件: LISURIDE; 3件: DRD2,
DRD3,
DRD4 💬		8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬2件: 6, 86
191 Melatonin 1件: Melatonin2件: Circadin; Melatonin; 2件: MTNR1A,
MTNR1B 💬		2件: Circadian entrainment, Neuroactive ligand-receptor interaction 💬12件: 6, 8, 13, 37, 46, 49, 72, 78, 90, 97, 145, 202
192 Memantine 1件: Memantine3件: EBIXA; Memantine; MEMANTINE HYDROCHLORIDE; 5件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬8件: 2, 6, 8, 13, 49, 127, 205, 206
193 Midodrine 1件: Midodrine2件: Midodrine; MIDODRINE HYDROCHLORIDE; 3件: ADRA1A,
ADRA1B,
ADRA1D 💬		7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬3件: 6, 17, 58
194 Montelukast 1件: Montelukast3件: MONTELUKAST; MONTELUKAST SODIUM; Singulair; 1件: CYSLTR1 💬2件: Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬8件: 6, 13, 46, 61, 63, 85, 98, 228
195 Moxifloxacin 1件: Moxifloxacin2件: Moxifloxacin; Moxifloxacin Hydrochloride; --9件: 2, 6, 46, 49, 85, 86, 113, 240, 299
196 Naloxone 1件: Naloxone2件: Naloxone; NALOXONE HYDROCHLORIDE; 3件: OPRD1,
OPRK1,
OPRM1 💬		5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬2件: 6, 226
197 Nortriptyline 1件: Nortriptyline2件: Nortriptyline; Nortriptyline hydrochloride; 2件: SLC6A2,
SLC6A4 💬		2件: Serotonergic synapse, Synaptic vesicle cycle 💬2件: 6, 226
198 Oxybuprocaine 1件: Oxybuprocaine1件: Oxybuprocaine; 5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬1件: 6
199 Pergolide 1件: Pergolide1件: PERGOLIDE; 2件: DRD1,
DRD2 💬		11件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6
200 Phenelzine 1件: Phenelzine1件: Nardil; 2件: MAOA,
MAOB 💬		14件: Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬1件: 6
201 Pioglitazone 1件: Pioglitazone1件: Pioglitazone; 1件: PPARG 💬11件: AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299
202 Propranolol 1件: Propranolol2件: Propanolol; Propranolol; 3件: ADRB1,
ADRB2,
ADRB3 💬		12件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, cAMP signaling pathway, cGMP-PKG signaling pathway 💬6件: 6, 158, 167, 227, 278, 296
203 Pyridoxine 1件: Pyridoxine2件: Pyridoxine; Vitamin B6; --5件: 6, 93, 145, 206, 320
204 Quetiapine 1件: Quetiapine2件: Quetiapine; Seroquel; 2件: DRD2,
HTR2A 💬		11件: Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬2件: 6, 13
205 Quinine 1件: Quinine0件: --1件: 6
206 Quinine dihydrochloride 1件: Quinine0件: --1件: 6
207 Rasagiline 1件: Rasagiline4件: Azilect; Rasagilina; Rasagiline; RASAGILINE MESYLATE; 1件: MAOB 💬14件: Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬6件: 2, 5, 6, 17, 58, 66
208 Remifentanil 1件: Remifentanil2件: Remifentanil; Remifentanyl; 1件: OPRM1 💬3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬2件: 6, 70
209 Ropinirole 1件: Ropinirole3件: Requip; Ropinirole; ROPINIROLE HYDROCHLORIDE; 3件: DRD2,
DRD3,
DRD4 💬		8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬4件: 2, 6, 74, 309
210 Rosuvastatin 1件: Rosuvastatin3件: Crestor; Rosuvastatin; ROSUVASTATIN CALCIUM; 1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬11件: 6, 18, 46, 49, 51, 56, 79, 96, 97, 271, 299
211 Sildenafil 1件: Sildenafil6件: Mysildecard; Revatio; Sildenafil; SILDENAFIL CITRATE; SILDENAFILO; Viagra; 1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬17件: 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301
212 Sitagliptin 1件: Sitagliptin1件: Sitagliptin; 1件: DPP4 💬1件: Protein digestion and absorption 💬4件: 6, 75, 233, 299
213 Solifenacin 1件: Solifenacin2件: Solifenacin; Solifenacin Succinate; 1件: CHRM3 💬11件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬3件: 6, 13, 53
214 Sulfanilamide 1件: Sulfanilamide0件: --4件: 6, 30, 60, 298
215 Tacrolimus 1件: Tacrolimus2件: Prograf; Tacrolimus; 5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬34件: 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
216 Terazosin 1件: Terazosin1件: Terazosin; 3件: ADRA1A,
ADRA1B,
ADRA1D 💬		7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 6
217 Trihexyphenidyl 1件: Trihexyphenidyl1件: Trihexyphenidyl; 5件: CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		13件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬2件: 5, 6
218 Trimethobenzamide 1件: Trimethobenzamide3件: Tigan; Trimethobenzamide; Trimethobenzamide Hydrochloride; --1件: 6
219 Varenicline 1件: Varenicline2件: Champix; Varenicline; 2件: CHRNA4,
CHRNB2 💬		4件: Chemical carcinogenesis - receptor activation, Cholinergic synapse, Neuroactive ligand-receptor interaction, Nicotine addiction 💬3件: 6, 18, 53
220 Venlafaxine 1件: Venlafaxine2件: Venlafaxine; VENLAFAXINE HYDROCHLORIDE; 2件: SLC6A2,
SLC6A4 💬		2件: Serotonergic synapse, Synaptic vesicle cycle 💬3件: 6, 13, 46
221 Warfarin 1件: Warfarin2件: Warfarin; Warfarin Sodium; 2件: NQO1,
VKORC1 💬		7件: Biosynthesis of cofactors, Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Metabolic pathways, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis 💬11件: 6, 8, 13, 19, 46, 49, 66, 85, 86, 88, 91
222 Yohimbine 1件: Yohimbine1件: Yohimbine; 3件: ADRA2A,
ADRA2B,
ADRA2C 💬		2件: Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬1件: 6
223 Zoledronic acid 1件: Zoledronic acid4件: Aclasta; Zoledronate; Zoledronic acid; Zometa; 1件: FDPS 💬4件: Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬13件: 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333
224 Zolpidem 1件: Zolpidem2件: Zolpidem; Zolpidem Tartrate; 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬3件: 5, 6, 46
225 Nilotinib 1件: Nilotinib2件: Nilotinib; Tasigna; 4件: ABL1,
KIT,
PDGFRA,
PDGFRB 💬		33件: Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Choline metabolism in cancer, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis 💬5件: 6, 8, 34, 51, 86
226 Perampanel 1件: Perampanel2件: Fycompa; Perampanel; 4件: GRIA1,
GRIA2,
GRIA3,
GRIA4 💬		16件: Amphetamine addiction, Amyotrophic lateral sclerosis, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Transcriptional misregulation in cancer, cAMP signaling pathway 💬3件: 2, 6, 144
227 German chamomile flower 1件: Chamomile2件: Chamomile; MATRICARIA FLOWER; --2件: 6, 97
228 Levomefolic acid 1件: Levomefolic acid1件: L-methylfolate; --2件: 6, 201
229 Linaclotide 1件: Linaclotide1件: Linaclotide; 1件: GUCY2C 💬2件: Metabolic pathways, Purine metabolism 💬2件: 6, 97
230 Pardoprunox 1件: Pardoprunox1件: Pardoprunox; 3件: DRD2,
DRD3,
HTR1A 💬		10件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬1件: 6
231 Mirabegron 1件: Mirabegron1件: Mirabegron; 1件: ADRB3 💬8件: Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, cGMP-PKG signaling pathway 💬4件: 6, 13, 53, 226
232 Nelotanserin 1件: Nelotanserin1件: Nelotanserin; 1件: HTR2A 💬5件: Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse 💬1件: 6
233 Saracatinib 1件: Saracatinib1件: Saracatinib; 2件: ABL1,
SRC 💬		49件: Adherens junction, Axon guidance, Bacterial invasion of epithelial cells, Bladder cancer, C-type lectin receptor signaling pathway, Cell cycle, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, GABAergic synapse, Gap junction, GnRH signaling pathway, Hepatitis B, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, MicroRNAs in cancer, Mitophagy - animal, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Oxytocin signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Platelet activation, Prolactin signaling pathway, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Thyroid hormone signaling pathway, Tight junction, Tuberculosis, VEGF signaling pathway, Viral carcinogenesis, Viral myocarditis, Yersinia infection 💬3件: 6, 89, 272
234 Preladenant 1件: Preladenant1件: Preladenant; 1件: ADORA2A 💬7件: Alcoholism, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway 💬1件: 6
235 Lixisenatide 1件: Lixisenatide1件: Lixisenatide; 1件: GLP1R 💬3件: Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬1件: 6
236 Bavisant 1件: Bavisant1件: Bavisant; 1件: HRH3 💬1件: Neuroactive ligand-receptor interaction 💬1件: 6
237 Pridopidine 1件: Pridopidine1件: Pridopidine; 1件: DRD2 💬8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬3件: 2, 6, 8
238 Semaglutide 1件: Semaglutide1件: Semaglutide; 1件: GLP1R 💬3件: Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬1件: 6
239 Suvorexant 1件: Suvorexant1件: Suvorexant; 2件: HCRTR1,
HCRTR2 💬		1件: Neuroactive ligand-receptor interaction 💬3件: 5, 6, 13
240 Glycerol phenylbutyrate 1件: Glycerol phenylbutyrate3件: Glycerol Phenylbutyrate; GT4P; RAVICTI; --3件: 6, 251, 299
241 Safinamide 1件: Safinamide3件: Safinamida; SAFINAMIDE; Xadago; 1件: MAOB 💬14件: Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬2件: 6, 17
242 Tozadenant 1件: Tozadenant1件: TOZADENANT; 1件: ADORA2A 💬7件: Alcoholism, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway 💬1件: 6
243 Vortioxetine 1件: Vortioxetine1件: Vortioxetine; 7件: HTR1A,
HTR3A,
HTR3B,
HTR3C,
HTR3D,
HTR3E,
SLC6A4 💬		5件: Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle, Taste transduction, cAMP signaling pathway 💬1件: 6
244 Masitinib 1件: Masitinib1件: Masitinib; 1件: KIT 💬11件: Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer, Hematopoietic cell lineage, MAPK signaling pathway, Melanogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway 💬6件: 2, 5, 6, 13, 46, 96
245 Pitolisant 1件: Pitolisant1件: Pitolisant; 1件: HRH3 💬1件: Neuroactive ligand-receptor interaction 💬3件: 6, 113, 193
246 Elobixibat 1件: Elobixibat1件: Elobixibat; 1件: SLC10A2 💬1件: Bile secretion 💬1件: 6
247 Opicapone 1件: Opicapone2件: Ongentys; OPICAPONE; 1件: COMT 💬4件: Dopaminergic synapse, Metabolic pathways, Steroid hormone biosynthesis, Tyrosine metabolism 💬1件: 6
248 Rasagiline tartrate 1件: Rasagiline4件: AZILECT; Rasagilina; RASAGILINE; RASAGILINE MESYLATE; 1件: MAOB 💬14件: Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬6件: 2, 5, 6, 17, 58, 66
249 Cannabidiol 1件: Cannabidiol4件: CANNABIDIOL; Epidiolex; Epidyolex; Sativex; 2件: CNR1,
CNR2 💬		4件: Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬20件: 2, 6, 8, 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271
250 Prasinezumab 1件: Prasinezumab1件: Prasinezumab; 1件: SNCA 💬3件: Alzheimer disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases 💬1件: 6
251 Tavapadon 1件: Tavapadon2件: PF-06649751; TAVAPADON; 2件: DRD1,
DRD5 💬		10件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, cAMP signaling pathway 💬1件: 6
252 Venglustat 1件: Venglustat2件: GENZ-682452; Venglustat; 1件: UGCG 💬2件: Metabolic pathways, Sphingolipid metabolism 💬3件: 6, 19, 67
253 Ampreloxetine 1件: Ampreloxetine1件: Ampreloxetine; 2件: SLC6A2,
SLC6A4 💬		2件: Serotonergic synapse, Synaptic vesicle cycle 💬2件: 6, 17
254 Foslevodopa 1件: Foslevodopa1件: Foslevodopa; 5件: DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		11件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6
255 Foscarbidopa 1件: Foscarbidopa1件: Foscarbidopa; --1件: 6
256 Valiloxybate 1件: Valiloxybate1件: Valiloxybate; 2件: GABBR1,
GABBR2 💬		7件: Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬1件: 6