Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	GABBR1	7件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, GABAergic synapse, Taste transd ...	D00241	Baclofen	8件: 2, 10, 13, 18, 65, 70, 149, 206
2	OPRD1	3件: cGMP-PKG signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interact ...	D05113	Naltrexone	13件: 6, 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226
3	OPRK1	1件: Neuroactive ligand-receptor interaction	D05113	Naltrexone	12件: 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226
4	OPRM1	3件: Neuroactive ligand-receptor interaction, Estrogen signaling pathway, Morphine addiction	D05113	Naltrexone	13件: 6, 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226
5	PGR	5件: Oocyte meiosis, Progesterone-mediated oocyte maturation, Estrogen signaling pathway, Chemical ca ...	D09567	Ulipristal	1件: 10
6	SCN1A	1件: Dopaminergic synapse	D08215	Mexiletine	3件: 10, 113, 114
7	SCN2A	1件: Taste transduction	D08215	Mexiletine	3件: 10, 113, 114
8	SCN3A	1件: Taste transduction	D08215	Mexiletine	3件: 10, 113, 114
9	SCN5A	1件: Adrenergic signaling in cardiomyocytes	D08215	Mexiletine	3件: 10, 113, 114
10	SCN9A	1件: Taste transduction	D08215	Mexiletine	3件: 10, 113, 114

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