Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	CSF3R	5件: Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, ...	D03235	Filgrastim	35件: 2, 6, 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 6 ...
2	EDNRA	7件: Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligan ...	D01227	Bosentan	10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212
3	EDNRA	7件: Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligan ...	D07538	Bosentan	10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212
4	EDNRB	6件: Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, ...	D01227	Bosentan	10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212
5	EDNRB	6件: Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, ...	D07538	Bosentan	10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212
6	SERPINC1	1件: Complement and coagulation cascades	D07510	Heparin	11件: 47, 60, 70, 84, 107, 224, 226, 280, 299, 316, 317
7	SNAP25	2件: Synaptic vesicle cycle, Insulin secretion	D00783	Botulinum toxin type A	14件: 2, 5, 6, 7, 13, 15, 17, 36, 47, 51, 70, 113, 149, 226

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