Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	CD52	-	D02802	Alemtuzumab	5件: 234, 283, 284, 285, 326
2	ABCD1	1件: Peroxisome	D12150	Elivaldogene autotemcel	1件: 20
3	POLA2	1件: DNA replication	D03546	Clofarabine	2件: 234, 326
4	IMPDH1	4件: Purine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism	D00752	Mycophenolate mofetil	34件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, ...
5	IMPDH1	4件: Purine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism	D05096	Mycophenolic acid	36件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, ...
6	IMPDH2	4件: Purine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism	D00752	Mycophenolate mofetil	34件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, ...
7	IMPDH2	4件: Purine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism	D05096	Mycophenolic acid	36件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, ...
8	POLA1	1件: DNA replication	D03546	Clofarabine	2件: 234, 326
9	HAO1	4件: Glyoxylate and dicarboxylate metabolism, Metabolic pathways, Carbon metabolism, Peroxisome	D11925	Lumasiran	1件: 234
10	PPARA (Full name: peroxisome proliferator activated receptor alpha)	10件: PPAR signaling pathway, cAMP signaling pathway, Adipocytokine signaling pathway, Glucagon signa ...	D00565	Fenofibrate	6件: 8, 79, 93, 94, 97, 265

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