Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Acetate [1] Acetate---[41] 1, 2, 6, 10, 13, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 171, 206, 222, 224, 225, 227, 235, 251, 265, 288, 298, 299
2 Acetylsalicylic acid [2] ACETYLSALICYLIC ACID; Aspirin[1] D00109 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251
3 Arginine [6] Arginina; Arginine; L-Arg; L-Arginin; L-arginine; R-Gene[1] D02982 --[12] 46, 58, 65, 67, 78, 96, 97, 98, 113, 210, 251, 299
4 Ataluren [2] ATALUREN; Translarna[1] D09323 --[6] 19, 113, 140, 246, 299, 329
5 ATYR-1940 [1] ATYR1940---[1] 113
6 Bisoprolol [2] Bisoprolol; Bisoprolol Fumarate[1] D02342 [1] ADRB1 💬[11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 58, 67, 86, 113
7 BLS-M22 [1] BLS-M22---[1] 113
8 BMN-044 [0] ---[1] 113
9 BMN-045 [2] BMN 045; PRO045---[1] 113
10 BMN-053 [1] BMN053---[1] 113
11 Bocidelpar [1] Bocidelpar[1] D12242 [1] PPARG 💬[11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[1] 113
12 Botulinum toxin type A [8] Botox; Botulinum toxin A; Botulinum toxin type A; BTX-A; Dysport; IncobotulinumtoxinA; OnabotulinumtoxinA; Xeomin[1] D00783 [1] SNAP25 💬[2] Insulin secretion, Synaptic vesicle cycle 💬[14] 2, 5, 6, 7, 13, 15, 17, 36, 47, 51, 70, 113, 149, 226
13 Calcifediol [2] 25-Hydroxyvitamin D3; CALCIFEDIOL[1] D00122 [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[2] 113, 299
14 Canakinumab [2] CANAKINUMAB; Ilaris[1] D09315 [1] IL1B 💬[44] AGE-RAGE signaling pathway in diabetic complications, African trypanosomiasis, Alcoholic liver disease, Alzheimer disease, Amoebiasis, Antifolate resistance, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Herpes simplex virus 1 infection, Human cytomegalovirus infection, IL-17 signaling pathway, Inflammatory bowel disease, Inflammatory mediator regulation of TRP channels, Influenza A, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Rheumatoid arthritis, Salmonella infection, Shigellosis, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Tuberculosis, Type I diabetes mellitus, Yersinia infection 💬[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269
15 CAP-1002 [1] CAP-1002---[1] 113
16 Carvedilol [1] Carvedilol[1] D00255 [5] ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
ADRB2 💬		[13] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 57, 86, 113, 210
17 Casimersen [1] CASIMERSEN[1] D11988 [1] DMD 💬[4] Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Viral myocarditis 💬[1] 113
18 Citrulline [1] Citrulline---[2] 86, 113
19 Creatine [1] Creatine---[11] 1, 2, 5, 6, 8, 46, 49, 50, 113, 156, 201
20 Cyclosporine [10] CICLOSPORIN; CICLOSPORINA; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine; Cyclosporine A; Ikervis; Neoral; Restasis[1] D00184 [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
21 Deflazacort [1] Deflazacort[1] D03671 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[2] 30, 113
22 Dexmedetomidine [4] Dexdor; DEXMEDETOMIDINA; Dexmedetomidine; DEXMEDETOMIDINE HYDROCHLORIDE[1] D00514 [3] ADRA2A,
ADRA2B,
ADRA2C 💬		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[14] 2, 4, 6, 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280
23 Doconexent [2] Docosahexaenoic acid; Docosahexanoic Acid---[10] 6, 46, 48, 49, 90, 94, 113, 240, 299, 301
24 Domagrozumab [1] PF-06252616[1] D11047 [1] MSTN 💬[1] Cytokine-cytokine receptor interaction 💬[1] 113
25 Drisapersen [1] Drisapersen[1] D10114 [1] DMD 💬[4] Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Viral myocarditis 💬[1] 113
26 Edasalonexent [1] EDASALONEXENT[1] D12181 [1] RELA 💬[76] AGE-RAGE signaling pathway in diabetic complications, Acute myeloid leukemia, Adipocytokine signaling pathway, Alcoholic liver disease, Alzheimer disease, Amoebiasis, Antifolate resistance, Apoptosis, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Chronic myeloid leukemia, Cocaine addiction, Coronavirus disease - COVID-19, Cytosolic DNA-sensing pathway, Diabetic cardiomyopathy, Epithelial cell signaling in Helicobacter pylori infection, Epstein-Barr virus infection, Fluid shear stress and atherosclerosis, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, Longevity regulating pathway, MAPK signaling pathway, Measles, Mitophagy - animal, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prolactin signaling pathway, Prostate cancer, RIG-I-like receptor signaling pathway, Ras signaling pathway, Relaxin signaling pathway, Salmonella infection, Shigellosis, Small cell lung cancer, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Viral carcinogenesis, Yersinia infection, cAMP signaling pathway 💬[1] 113
27 Enalapril [2] Enalapril; Enalapril Maleate[1] D07892 [1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[6] 19, 46, 66, 113, 210, 222
28 Epicatechin [1] Epicatechin---[2] 86, 113
29 Epigallocatechin [1] Epigallocatechin---[5] 8, 13, 28, 85, 113
30 Epigallocatechin gallate [3] EGCG; Epigallocatechin gallate; Epigallocatechin-3-gallate---[9] 6, 8, 13, 17, 28, 85, 113, 206, 299
31 Eplerenone [1] Eplerenone[1] D01115 [1] NR3C2 💬[1] Aldosterone-regulated sodium reabsorption 💬[4] 75, 113, 210, 215
32 Esomeprazole [3] Esomeprazole; Nexium; Omeprazole[1] D07917 [2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[8] 13, 46, 86, 98, 107, 113, 298, 299
33 Eteplirsen [2] ETEPLIRSEN; Exondys 51[1] D09900 [1] DMD 💬[4] Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Viral myocarditis 💬[1] 113
34 Ezutromid [1] Ezutromid---[1] 113
35 Filgrastim [7] Filgrastim; Filgrastim Hexal; G-CSF; Granulocyte Colony Stimulating Factor; Neupogen; TEVAGRASTIM; Zarzio[1] D03235 [1] CSF3R 💬[5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[35] 2, 6, 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331
36 Fordadistrogene movaparvovec [1] Fordadistrogene movaparvovec---[1] 113
37 Gentamicin [2] Gentamicin; Gentamicin Sulfate[1] D08013 --[3] 36, 113, 299
38 Givinostat [1] Givinostat---[2] 107, 113
39 Gold [1] Gold---[43] 2, 5, 6, 13, 17, 34, 35, 46, 49, 50, 53, 58, 63, 65, 68, 76, 84, 86, 91, 93, 95, 96, 97, 98, 113, 137, 158, 162, 167, 171, 193, 218, 222, 224, 226, 227, 230, 271, 291, 296, 298, 310, 318
40 Golodirsen [2] GOLODIRSEN; Vyondys 53[1] D11707 [1] DMD 💬[4] Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Viral myocarditis 💬[1] 113
41 Guanidine [1] Guanidine---[1] 113
42 Human Umbilical Cord Mesenchymal Stem Cells [4] Human Umbilical Cord Mesenchymal Stem Cells; Mesenchymal Stromal Cells; UC-MSCs; WJ-MSCs---[13] 2, 13, 36, 46, 49, 51, 60, 96, 97, 107, 113, 274, 284
43 Ibuprofen [2] Ibuprofen; IBUPROFEN 200MG[1] D00126 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[7] 13, 46, 65, 107, 113, 271, 299
44 Icosapent [2] Eicosapentaenoic acid; Icosapent[1] D08061 --[11] 8, 46, 48, 49, 96, 97, 113, 296, 297, 301, 338
45 Idebenone [2] Idebenone; Raxone[1] D01750 --[6] 6, 8, 13, 18, 113, 302
46 Ifetroban [1] Ifetroban[1] D04500 [1] TBXA2R 💬[3] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Platelet activation 💬[2] 85, 113
47 Isosorbide [1] Isosorbide[1] D00347 --[1] 113
48 Isosorbide dinitrate [2] Isosorbide; ISOSORBIDE DINITRATE[1] D00516 --[1] 113
49 Ketamine [2] Ketamine; NMDA[1] D08098 [5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[8] 2, 4, 6, 13, 70, 113, 156, 215
50 L-arginine [1] L-arginine[1] D02982 --[8] 46, 67, 78, 96, 97, 98, 113, 299
51 L-Glutamine [2] Glutamine; L-Glutamine[1] D00015 --[8] 87, 89, 96, 97, 113, 222, 245, 299
52 Lisinopril [2] LISINOPRIL; ZESTRIL[2] D00362 ,
D08131 		[1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[7] 19, 46, 49, 66, 67, 113, 222
53 Lonafarnib [1] Lonafarnib[1] D04768 [2] FNTA,
FNTB 💬		[1] Terpenoid backbone biosynthesis 💬[2] 113, 333
54 Losartan [3] Cozaar; Losartan; LOSARTAN POTASSIUM[1] D08146 [1] AGTR1 💬[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
55 Losmapimod [1] LOSMAPIMOD[1] D09639 [4] MAPK11,
MAPK12,
MAPK13,
MAPK14 💬		[62] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Alcoholic liver disease, Amyotrophic lateral sclerosis, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Dopaminergic synapse, Endocrine resistance, Epithelial cell signaling in Helicobacter pylori infection, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hepatitis B, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, IL-17 signaling pathway, Inflammatory mediator regulation of TRP channels, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Leukocyte transendothelial migration, Lipid and atherosclerosis, MAPK signaling pathway, NOD-like receptor signaling pathway, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Oocyte meiosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Platelet activation, Prion disease, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rap1 signaling pathway, Relaxin signaling pathway, Retrograde endocannabinoid signaling, Salmonella infection, Shigellosis, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Thermogenesis, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, VEGF signaling pathway, Yersinia infection 💬[2] 113, 222
56 Mannitol [4] Aridol; Bronchitol; Mannite; Mannitol[1] D00062 --[7] 6, 13, 28, 60, 96, 113, 299
57 Metformin [5] Metformin; Metformin HCl; Metformin hydrochloride; Metformina; Metformine[1] D04966 [2] PRKAA1,
PRKAA2 💬		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[25] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301
58 Methylphenidate [3] Methylphenidate; METHYLPHENIDATE HYDROCHLORIDE; Ritalin[1] D04999 [2] SLC6A2,
SLC6A3 💬		[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[7] 6, 13, 34, 84, 113, 179, 206
59 Metoprolol [2] Metoprolol; METOPROLOL SUCCINATE[1] D02358 [1] ADRB1 💬[11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[6] 17, 57, 58, 113, 193, 226
60 Mexiletine [4] Mexiletina; Mexiletine; Mexitil; Namuscla[1] D08215 [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[5] 1, 2, 10, 113, 114
61 Modafinil [2] Modafinil; Provigil[1] D01832 --[5] 6, 13, 49, 93, 113
62 Moxifloxacin [2] Moxifloxacin; Moxifloxacin Hydrochloride[1] D08237 --[9] 2, 6, 46, 49, 85, 86, 113, 240, 299
63 Nebivolol [1] Nebivolol[1] D05127 [1] ADRB1 💬[11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 17, 85, 113, 167
64 Nitrate [1] Nitrate[1] D02313 --[4] 58, 67, 113, 299
65 Omigapil [1] Omigapil---[1] 113
66 Oxatomide [1] Oxatomide[1] D01773 [1] ALOX5 💬[6] Arachidonic acid metabolism, Fc epsilon RI signaling pathway, Metabolic pathways, Ovarian steroidogenesis, Serotonergic synapse, Toxoplasmosis 💬[1] 113
67 Pamrevlumab [1] PAMREVLUMAB[1] D10969 [1] CCN2 💬[2] Apelin signaling pathway, Hippo signaling pathway 💬[2] 85, 113
68 Pemirolast [1] PEMIROLAST[1] D07476 --[1] 113
69 Pentoxifylline [1] Pentoxifylline[1] D00501 --[12] 26, 56, 84, 86, 93, 96, 97, 113, 220, 222, 296, 298
70 Perindopril [2] Coversyl; PERINDOPRIL[1] D03753 [1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[4] 58, 113, 167, 222
71 Pitolisant [1] Pitolisant[1] D10749 [1] HRH3 💬[1] Neuroactive ligand-receptor interaction 💬[3] 6, 113, 193
72 Prasterone [3] Dehydroepiandrosterone; DHEA; Prasterone[1] D08409 [3] AR,
ESR1,
ESR2 💬		[12] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Oocyte meiosis, Pathways in cancer, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[6] 49, 53, 83, 86, 96, 113
73 Prednisolone [3] Prednisolona; Prednisolone; Prednisolonum[1] D00472 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[42] 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300
74 Prednisone [3] Prednisona; Prednisone; RAYOS[1] D00473 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[45] 2, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331
75 Ramipril [1] Ramipril[1] D00421 [1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[7] 46, 49, 66, 67, 113, 218, 257
76 Ranolazine [3] RANEXA; Ranolazina; Ranolazine[1] D05700 --[6] 2, 58, 86, 96, 113, 114
77 Resveratrol [1] Resveratrol---[6] 2, 8, 18, 89, 97, 113
78 rhIGFBP-3 [1] RhIGFBP-3---[2] 113, 195
79 Rimeporide [1] Rimeporide---[1] 113
80 Risedronic acid [3] Risedronate; Risedronate sodium; Risedronic acid[1] D08484 [1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[9] 46, 50, 66, 93, 95, 96, 107, 113, 274
81 Salbutamol [3] Albuterol; Salbutamol; Ventolin[1] D02147 [1] ADRB2 💬[9] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[12] 3, 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299
82 Sildenafil [6] Mysildecard; Revatio; Sildenafil; Sildenafil Citrate; SILDENAFILO; VIAGRA[1] D08514 [1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[17] 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301
83 Sodium nitrate [1] Sodium Nitrate---[2] 58, 113
84 Somatotropin [17] Genotropin; Growth hormone; Human growth hormone; Humatrope; Norditropin; Norditropin SimpleXx; NUTROPIN; Nutropin AQ; NutropinAq; OMNITROPE; Recombinant human growth hormone; RhGH; SAIZEN; Somatotropin; Somatropin; SOMATROPINA; Zomacton---[25] 2, 3, 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 246, 265, 274, 276, 299, 337
85 Spironolactone [1] SPIRONOLACTONE[1] D00443 [1] NR3C2 💬[1] Aldosterone-regulated sodium reabsorption 💬[8] 46, 58, 67, 86, 113, 210, 218, 225
86 SRP-9003 [1] SRP-9003---[1] 113
87 Stamulumab [1] MYO-029[1] D05917 [1] MSTN 💬[1] Cytokine-cytokine receptor interaction 💬[1] 113
88 Tacrolimus [2] Prograf; Tacrolimus[2] D00107 ,
D08556 		[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
89 Tadalafil [4] Adcirca; CIALIS; Tadalafil; TADALAFILO[1] D02008 [1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[7] 6, 51, 75, 84, 86, 113, 210
90 Tamoxifen [2] Tamoxifen; TAMOXIFEN CITRATE[1] D08559 [2] ESR1,
ESR2 💬		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[3] 2, 113, 227
91 Testosterone [1] Testosterone[1] D00075 [1] AR 💬[4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[8] 1, 2, 3, 13, 60, 76, 78, 113
92 Testosterone decanoate [1] Testosterone decanoate[1] D08573 [1] AR 💬[4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[1] 113
93 Testosterone enanthate [1] Testosterone Enanthate[1] D00958 [1] AR 💬[4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[1] 113
94 Testosterone isocaproate [1] Testosterone isocaproate---[1] 113
95 Testosterone phenylpropionate [1] Testosterone phenylpropionate[1] D08574 [1] AR 💬[4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[1] 113
96 Testosterone propionate [1] Testosterone propionate[1] D00959 [1] AR 💬[4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[1] 113
97 Tetracosactide [4] Cosyntropin; Synacthen Depot; Tetracosactide; Tetracosactrin[1] D00284 [1] MC2R 💬[5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[5] 78, 83, 113, 145, 222
98 Tideglusib [1] Tideglusib---[2] 5, 113
99 Tranilast [1] Tranilast[1] D02027 --[4] 46, 84, 106, 113
100 Trehalose [2] Cabaletta; Trehalose---[4] 2, 6, 18, 113
101 Ubidecarenone [3] Coenzyme Q-10; Coenzyme Q10; CoQ10[1] D01065 --[12] 2, 5, 6, 8, 10, 18, 46, 57, 86, 113, 214, 215
102 Vamorolone [1] Vamorolone[1] D11000 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[2] 97, 113
103 Viltolarsen [1] VILTOLARSEN[1] D11528 [1] DMD 💬[4] Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Viral myocarditis 💬[1] 113
104 Zildistrogene varoparvovec [1] RAAV9-CK8-h-µD5---[1] 113
105 Zinc [3] Nicotinamide; Wilzin; Zinc---[4] 2, 113, 171, 299