Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Human cytomegalovirus infection 💬
 [1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
2 Human cytomegalovirus infection 💬
 [4] CCL2, IL1B, IL6, TNF 💬 D01583 💬 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
3 Human cytomegalovirus infection 💬
 [1] CCR5 💬 D09878 💬 Cenicriviroc [1] 94 💬
4 Human cytomegalovirus infection 💬
 [1] CCR5 💬 D06670 💬 Maraviroc [2] 46, 84 💬
5 Human cytomegalovirus infection 💬
 [2] CDK4, CDK6 💬 D10688 💬 Abemaciclib [1] 34 💬
6 Human cytomegalovirus infection 💬
 [1] CXCR2 💬 D08984 💬 Reparixin [2] 298, 299 💬
7 Human cytomegalovirus infection 💬
 [1] CXCR4 💬 D08971 💬 Plerixafor [5] 19, 20, 65, 285, 299 💬
8 Human cytomegalovirus infection 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
9 Human cytomegalovirus infection 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
10 Human cytomegalovirus infection 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
11 Human cytomegalovirus infection 💬
 [1] EGFR 💬 D11251 💬 Icotinib [1] 34 💬
12 Human cytomegalovirus infection 💬
 [1] EGFR 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
13 Human cytomegalovirus infection 💬
 [1] EGFR 💬 D08950 💬 Neratinib [1] 34 💬
14 Human cytomegalovirus infection 💬
 [1] EGFR 💬 D11772 💬 Tesevatinib [1] 67 💬
15 Human cytomegalovirus infection 💬
 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 D09662 💬 Rontalizumab [1] 49 💬
16 Human cytomegalovirus infection 💬
 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 D09668 💬 Sifalimumab [1] 49 💬
17 Human cytomegalovirus infection 💬
 [1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
18 Human cytomegalovirus infection 💬
 [1] IL1B 💬 D09911 💬 Gevokizumab [4] 41, 50, 56, 269 💬
19 Human cytomegalovirus infection 💬
 [1] IL1B 💬 D06635 💬 Rilonacept [4] 51, 106, 107, 266 💬
20 Human cytomegalovirus infection 💬
 [1] IL1R1 💬 D02934 💬 Anakinra [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
21 Human cytomegalovirus infection 💬
 [1] IL6 💬 D12487 💬 Olokizumab [2] 46, 96 💬
22 Human cytomegalovirus infection 💬
 [1] IL6 💬 D09669 💬 Siltuximab [2] 28, 331 💬
23 Human cytomegalovirus infection 💬
 [1] IL6 💬 D10080 💬 Sirukumab [2] 41, 46 💬
24 Human cytomegalovirus infection 💬
 [2] IL6, TNF 💬 D08976 💬 Pomalidomide [5] 28, 51, 85, 227, 331 💬
25 Human cytomegalovirus infection 💬
 [1] IL6R 💬 D10161 💬 Sarilumab [5] 41, 46, 84, 107, 271 💬
26 Human cytomegalovirus infection 💬
 [1] IL6R 💬 D11079 💬 Satralizumab [3] 11, 13, 86 💬
27 Human cytomegalovirus infection 💬
 [1] IL6R 💬 D02596 💬 Tocilizumab [21]  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
28 Human cytomegalovirus infection 💬
 [1] JAK1 💬 D11400 💬 Abrocitinib [1] 84 💬
29 Human cytomegalovirus infection 💬
 [1] JAK1 💬 D10308 💬 Baricitinib [13]  2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
30 Human cytomegalovirus infection 💬
 [1] JAK1 💬 D10871 💬 Filgotinib [6] 46, 53, 96, 97, 222, 271 💬
31 Human cytomegalovirus infection 💬
 [1] JAK1 💬 D10944 💬 Itacitinib [4] 46, 51, 97, 228 💬
32 Human cytomegalovirus infection 💬
 [1] JAK1 💬 D10653 💬 Peficitinib [1] 46 💬
33 Human cytomegalovirus infection 💬
 [1] JAK1 💬 D09959 💬 Ruxolitinib [3] 60, 65, 228 💬
34 Human cytomegalovirus infection 💬
 [1] JAK1 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
35 Human cytomegalovirus infection 💬
 [1] JAK1 💬 D10994 💬 Upadacitinib [8] 40, 41, 46, 49, 96, 97, 107, 271 💬
36 Human cytomegalovirus infection 💬
 [2] MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib [1] 34 💬
37 Human cytomegalovirus infection 💬
 [2] MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib [1] 280 💬
38 Human cytomegalovirus infection 💬
 [2] MAP2K1, MAP2K2 💬 D11675 💬 Mirdametinib [1] 34 💬
39 Human cytomegalovirus infection 💬
 [2] MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib [1] 34 💬
40 Human cytomegalovirus infection 💬
 [2] MAP2K1, MAP2K2 💬 D10175 💬 Trametinib [4]  2 , 34, 279, 280 💬
41 Human cytomegalovirus infection 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D09639 💬 Losmapimod [2] 113, 222 💬
42 Human cytomegalovirus infection 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
43 Human cytomegalovirus infection 💬
 [1] MTOR 💬 D02714 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
44 Human cytomegalovirus infection 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
45 Human cytomegalovirus infection 💬
 [1] MTOR 💬 D06068 💬 Temsirolimus [1] 13 💬
46 Human cytomegalovirus infection 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [5] 46, 51, 53, 271, 300 💬
47 Human cytomegalovirus infection 💬
 [1] PDGFRA 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
48 Human cytomegalovirus infection 💬
 [1] PDGFRA 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
49 Human cytomegalovirus infection 💬
 [1] PDGFRA 💬 D10481 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
50 Human cytomegalovirus infection 💬
 [1] PDGFRA 💬 D08552 💬 Sunitinib [2] 28, 34 💬
51 Human cytomegalovirus infection 💬
 [1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
52 Human cytomegalovirus infection 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
53 Human cytomegalovirus infection 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
54 Human cytomegalovirus infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
55 Human cytomegalovirus infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D05480 💬 Pimecrolimus [1] 160 💬
56 Human cytomegalovirus infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
57 Human cytomegalovirus infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
58 Human cytomegalovirus infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D09033 💬 Voclosporin [2] 49, 222 💬
59 Human cytomegalovirus infection 💬
 [1] PRKCB 💬 D11935 💬 Enzastaurin [1] 168 💬
60 Human cytomegalovirus infection 💬
 [1] PTGER1 💬 D00180 💬 Alprostadil [2] 51, 70 💬
61 Human cytomegalovirus infection 💬
 [1] PTGER1 💬 D02722 💬 Limaprost [1] 70 💬
62 Human cytomegalovirus infection 💬
 [3] PTGER2, PTGER3, PTGER4 💬 D00419 💬 Misoprostol [3] 46, 70, 271 💬
63 Human cytomegalovirus infection 💬
 [1] PTGS2 💬 D01545 💬 Aceclofenac [1] 46 💬
64 Human cytomegalovirus infection 💬
 [1] PTGS2 💬 D00217 💬 Acetaminophen [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
65 Human cytomegalovirus infection 💬
 [1] PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
66 Human cytomegalovirus infection 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
67 Human cytomegalovirus infection 💬
 [1] PTGS2 💬 D07816 💬 Diclofenac [5] 13, 34, 46, 78, 271 💬
68 Human cytomegalovirus infection 💬
 [1] PTGS2 💬 D00130 💬 Diflunisal [1] 28 💬
69 Human cytomegalovirus infection 💬
 [1] PTGS2 💬 D00315 💬 Etodolac [1] 46 💬
70 Human cytomegalovirus infection 💬
 [1] PTGS2 💬 D03710 💬 Etoricoxib [2] 46, 271 💬
71 Human cytomegalovirus infection 💬
 [1] PTGS2 💬 D00330 💬 Flurbiprofen [3] 13, 21, 46 💬
72 Human cytomegalovirus infection 💬
 [1] PTGS2 💬 D00126 💬 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299 💬
73 Human cytomegalovirus infection 💬
 [1] PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
74 Human cytomegalovirus infection 💬
 [1] PTGS2 💬 D00132 💬 Ketoprofen [1] 46 💬
75 Human cytomegalovirus infection 💬
 [1] PTGS2 💬 D08104 💬 Ketorolac [2] 70, 226 💬
76 Human cytomegalovirus infection 💬
 [1] PTGS2 💬 D08149 💬 Loxoprofen [2] 46, 271 💬
77 Human cytomegalovirus infection 💬
 [1] PTGS2 💬 D03714 💬 Lumiracoxib [1] 46 💬
78 Human cytomegalovirus infection 💬
 [1] PTGS2 💬 D00969 💬 Meloxicam [4] 46, 49, 271, 296 💬
79 Human cytomegalovirus infection 💬
 [1] PTGS2 💬 D00118 💬 Naproxen [4] 13, 46, 107, 271 💬
80 Human cytomegalovirus infection 💬
 [1] PTGS2 💬 D01049 💬 Nimesulide [1] 46 💬
81 Human cytomegalovirus infection 💬
 [1] PTGS2 💬 D03716 💬 Parecoxib [2] 46, 271 💬
82 Human cytomegalovirus infection 💬
 [1] PTGS2 💬 D00568 💬 Rofecoxib [1] 46 💬
83 Human cytomegalovirus infection 💬
 [1] PTGS2 💬 D00428 💬 Salsalate [1]  5  💬
84 Human cytomegalovirus infection 💬
 [1] PTGS2 💬 D00120 💬 Sulindac [1] 206 💬
85 Human cytomegalovirus infection 💬
 [1] PTGS2 💬 D01183 💬 Tolfenamic acid [1]  5  💬
86 Human cytomegalovirus infection 💬
 [1] PTGS2 💬 D02709 💬 Valdecoxib [1] 46 💬
87 Human cytomegalovirus infection 💬
 [1] RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
88 Human cytomegalovirus infection 💬
 [1] RELA 💬 D12181 💬 Edasalonexent [1] 113 💬
89 Human cytomegalovirus infection 💬
 [2] ROCK1, ROCK2 💬 D07941 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
90 Human cytomegalovirus infection 💬
 [1] ROCK2 💬 D11815 💬 Belumosudil [2] 51, 85 💬
91 Human cytomegalovirus infection 💬
 [1] SRC 💬 D03252 💬 Bosutinib [2]  2 , 67 💬
92 Human cytomegalovirus infection 💬
 [1] SRC 💬 D03658 💬 Dasatinib [2] 51, 85 💬
93 Human cytomegalovirus infection 💬
 [1] SRC 💬 D06414 💬 Dasatinib [2] 51, 85 💬
94 Human cytomegalovirus infection 💬
 [1] SRC 💬 D09664 💬 Saracatinib [3]  6 , 89, 272 💬
95 Human cytomegalovirus infection 💬
 [1] TNF 💬 D02597 💬 Adalimumab [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
96 Human cytomegalovirus infection 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
97 Human cytomegalovirus infection 💬
 [1] TNF 💬 D00742 💬 Etanercept [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
98 Human cytomegalovirus infection 💬
 [1] TNF 💬 D04358 💬 Golimumab [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
99 Human cytomegalovirus infection 💬
 [1] TNF 💬 D02598 💬 Infliximab [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
100 Human cytomegalovirus infection 💬
 [1] TNF 💬 D04687 💬 Lenalidomide [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
101 Human cytomegalovirus infection 💬
 [1] TNF 💬 D09944 💬 Ozoralizumab [1] 46 💬
102 Human cytomegalovirus infection 💬
 [1] TNF 💬 D05393 💬 Pegsunercept [1] 46 💬
103 Human cytomegalovirus infection 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
104 Human cytomegalovirus infection 💬
 [1] VEGFA 💬 D09574 💬 Aflibercept [2] 90, 166 💬
105 Human cytomegalovirus infection 💬
 [1] VEGFA 💬 D06409 💬 Bevacizumab [6] 13, 34, 85, 87, 227, 280 💬
106 Human cytomegalovirus infection 💬
 [1] VEGFA 💬 D05697 💬 Ranibizumab [4] 34, 166, 227, 301 💬