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KEGG GENES
KEGG PATHWAY
KEGG DRUG
DrugBank
指定難病告示番号
1
MAPK14
💬
1. MAPK14
×
Name
Full Name
MAPK14
mitogen-activated protein kinase 14
62件:
Endocrine resistance
Endocrine resistance
,
MAPK signaling pathway
,
Rap1 signaling pathway
,
FoxO signaling pathway
,
Sphingolipid signaling pathway
,
Oocyte meiosis
,
Cellular senescence
,
Adrenergic signaling in cardiomyocytes
,
VEGF signaling pathway
,
Osteoclast differentiation
,
Signaling pathways regulating pluripotency of stem cells
,
Platelet activation
,
Neutrophil extracellular trap formation
,
Toll-like receptor signaling pathway
,
NOD-like receptor signaling pathway
,
RIG-I-like receptor signaling pathway
,
C-type lectin receptor signaling pathway
,
IL-17 signaling pathway
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
T cell receptor signaling pathway
,
Fc epsilon RI signaling pathway
,
TNF signaling pathway
,
Leukocyte transendothelial migration
,
Thermogenesis
,
Neurotrophin signaling pathway
,
Retrograde endocannabinoid signaling
,
Dopaminergic synapse
,
Inflammatory mediator regulation of TRP channels
,
GnRH signaling pathway
,
Progesterone-mediated oocyte maturation
,
Prolactin signaling pathway
,
Relaxin signaling pathway
,
Non-alcoholic fatty liver disease
,
AGE-RAGE signaling pathway in diabetic complications
,
Growth hormone synthesis, secretion and action
,
Alcoholic liver disease
,
Amyotrophic lateral sclerosis
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Epithelial cell signaling in Helicobacter pylori infection
,
Pathogenic Escherichia coli infection
,
Shigellosis
,
Salmonella infection
,
Pertussis
,
Yersinia infection
,
Leishmaniasis
,
Chagas disease
,
Toxoplasmosis
,
Tuberculosis
,
Hepatitis B
,
Human cytomegalovirus infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Epstein-Barr virus infection
,
Human immunodeficiency virus 1 infection
,
Coronavirus disease - COVID-19
,
Proteoglycans in cancer
,
Chemical carcinogenesis - reactive oxygen species
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
Diabetic cardiomyopathy
,
Lipid and atherosclerosis
,
Fluid shear stress and atherosclerosis
62件:
Endocrine resistance
,
MAPK signaling pathway
,
Rap1 signaling pathway
,
FoxO signaling pathway
,
S
...
Losmapimod
Losmapimod
💬
1. MAPK14
×
Name
Other Names
Losmapimod
Losmapimod (USAN/INN)
ロスマピモド
Losmapimod
2件:
113
113
,
222
💬
1. MAPK14
×
告示番号
日本語名
英語名
113
筋ジストロフィー
Muscular dystrophy
222
一次性ネフローゼ症候群
Primary nephrotic syndrome
2
MAPK14
💬
2. MAPK14
×
Name
Full Name
MAPK14
mitogen-activated protein kinase 14
62件:
Endocrine resistance
Endocrine resistance
,
MAPK signaling pathway
,
Rap1 signaling pathway
,
FoxO signaling pathway
,
Sphingolipid signaling pathway
,
Oocyte meiosis
,
Cellular senescence
,
Adrenergic signaling in cardiomyocytes
,
VEGF signaling pathway
,
Osteoclast differentiation
,
Signaling pathways regulating pluripotency of stem cells
,
Platelet activation
,
Neutrophil extracellular trap formation
,
Toll-like receptor signaling pathway
,
NOD-like receptor signaling pathway
,
RIG-I-like receptor signaling pathway
,
C-type lectin receptor signaling pathway
,
IL-17 signaling pathway
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
T cell receptor signaling pathway
,
Fc epsilon RI signaling pathway
,
TNF signaling pathway
,
Leukocyte transendothelial migration
,
Thermogenesis
,
Neurotrophin signaling pathway
,
Retrograde endocannabinoid signaling
,
Dopaminergic synapse
,
Inflammatory mediator regulation of TRP channels
,
GnRH signaling pathway
,
Progesterone-mediated oocyte maturation
,
Prolactin signaling pathway
,
Relaxin signaling pathway
,
Non-alcoholic fatty liver disease
,
AGE-RAGE signaling pathway in diabetic complications
,
Growth hormone synthesis, secretion and action
,
Alcoholic liver disease
,
Amyotrophic lateral sclerosis
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Epithelial cell signaling in Helicobacter pylori infection
,
Pathogenic Escherichia coli infection
,
Shigellosis
,
Salmonella infection
,
Pertussis
,
Yersinia infection
,
Leishmaniasis
,
Chagas disease
,
Toxoplasmosis
,
Tuberculosis
,
Hepatitis B
,
Human cytomegalovirus infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Epstein-Barr virus infection
,
Human immunodeficiency virus 1 infection
,
Coronavirus disease - COVID-19
,
Proteoglycans in cancer
,
Chemical carcinogenesis - reactive oxygen species
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
Diabetic cardiomyopathy
,
Lipid and atherosclerosis
,
Fluid shear stress and atherosclerosis
62件:
Endocrine resistance
,
MAPK signaling pathway
,
Rap1 signaling pathway
,
FoxO signaling pathway
,
S
...
Neflamapimod
Neflamapimod
💬
2. MAPK14
×
Name
Other Names
Neflamapimod
Neflamapimod (USAN)
ネフラマピモド
Neflamapimod
1件:
8
8
💬
2. MAPK14
×
告示番号
日本語名
英語名
8
ハンチントン病
Huntington disease
3
S1PR1
💬
3. S1PR1
×
Name
Full Name
S1PR1
sphingosine-1-phosphate receptor 1
3件:
FoxO signaling pathway
FoxO signaling pathway
,
Sphingolipid signaling pathway
,
Neuroactive ligand-receptor interaction
Fingolimod
Fingolimod
💬
3. S1PR1
×
Name
Other Names
Fingolimod
Fingolimod (INN)
Gilenya (TN)
フィンゴリモド
Fingolimod
3件:
13
13
,
14
,
156
💬
3. S1PR1
×
告示番号
日本語名
英語名
13
多発性硬化症／視神経脊髄炎
Multiple sclerosis/Neuromyelitis optica
14
慢性炎症性脱髄性多発神経炎／多巣性運動ニューロパチー
Chronic inflammatory demyelinating polyneuropathy
156
レット症候群
Rett syndrome
4
S1PR1
💬
4. S1PR1
×
Name
Full Name
S1PR1
sphingosine-1-phosphate receptor 1
3件:
FoxO signaling pathway
FoxO signaling pathway
,
Sphingolipid signaling pathway
,
Neuroactive ligand-receptor interaction
Amiselimod
Amiselimod
💬
4. S1PR1
×
Name
Other Names
Amiselimod
Amiselimod (USAN/INN)
アミセリモド
Amiselimod
1件:
97
97
💬
4. S1PR1
×
告示番号
日本語名
英語名
97
潰瘍性大腸炎
Ulcerative colitis
5
S1PR1
💬
5. S1PR1
×
Name
Full Name
S1PR1
sphingosine-1-phosphate receptor 1
3件:
FoxO signaling pathway
FoxO signaling pathway
,
Sphingolipid signaling pathway
,
Neuroactive ligand-receptor interaction
Etrasimod
Etrasimod
💬
5. S1PR1
×
Name
Other Names
Etrasimod
Etrasimod (USAN)
エトラシモド
Etrasimod
3件:
96
96
,
97
,
98
💬
5. S1PR1
×
告示番号
日本語名
英語名
96
クローン病;回腸末端炎
Crohn disease
97
潰瘍性大腸炎
Ulcerative colitis
98
好酸球性消化管疾患
Eosinophilic gastrointestinal disease
6
S1PR1
💬
6. S1PR1
×
Name
Full Name
S1PR1
sphingosine-1-phosphate receptor 1
3件:
FoxO signaling pathway
FoxO signaling pathway
,
Sphingolipid signaling pathway
,
Neuroactive ligand-receptor interaction
Ozanimod
Ozanimod
💬
6. S1PR1
×
Name
Other Names
Ozanimod
Ozanimod (USAN/INN)
オザニモド
Ozanimod
3件:
13
13
,
96
,
97
💬
6. S1PR1
×
告示番号
日本語名
英語名
13
多発性硬化症／視神経脊髄炎
Multiple sclerosis/Neuromyelitis optica
96
クローン病;回腸末端炎
Crohn disease
97
潰瘍性大腸炎
Ulcerative colitis
7
S1PR1
💬
7. S1PR1
×
Name
Full Name
S1PR1
sphingosine-1-phosphate receptor 1
3件:
FoxO signaling pathway
FoxO signaling pathway
,
Sphingolipid signaling pathway
,
Neuroactive ligand-receptor interaction
Ponesimod
Ponesimod
💬
7. S1PR1
×
Name
Other Names
Ponesimod
Ponesimod (USAN/INN)
Ponvory (TN)
ポネシモド
Ponesimod
1件:
13
13
💬
7. S1PR1
×
告示番号
日本語名
英語名
13
多発性硬化症／視神経脊髄炎
Multiple sclerosis/Neuromyelitis optica
8
S1PR1
💬
8. S1PR1
×
Name
Full Name
S1PR1
sphingosine-1-phosphate receptor 1
3件:
FoxO signaling pathway
FoxO signaling pathway
,
Sphingolipid signaling pathway
,
Neuroactive ligand-receptor interaction
Cenerimod
Cenerimod
💬
8. S1PR1
×
Name
Other Names
Cenerimod
Cenerimod (USAN/INN)
セネリモド
Cenerimod
1件:
49
49
💬
8. S1PR1
×
告示番号
日本語名
英語名
49
全身性エリテマトーデス
Systemic lupus erythematosus
9
S1PR1
💬
9. S1PR1
×
Name
Full Name
S1PR1
sphingosine-1-phosphate receptor 1
3件:
FoxO signaling pathway
FoxO signaling pathway
,
Sphingolipid signaling pathway
,
Neuroactive ligand-receptor interaction
Siponimod
Siponimod
💬
9. S1PR1
×
Name
Other Names
Siponimod
Siponimod (USAN/INN)
シポニモド
Siponimod
2件:
13
13
,
50
💬
9. S1PR1
×
告示番号
日本語名
英語名
13
多発性硬化症／視神経脊髄炎
Multiple sclerosis/Neuromyelitis optica
50
皮膚筋炎／多発性筋炎
Dermatomyositis
10
EGFR
💬
10. EGFR
×
Name
Full Name
EGFR
epidermal growth factor receptor
48件:
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
MAPK signaling pathway
,
ErbB signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Calcium signaling pathway
,
HIF-1 signaling pathway
,
FoxO signaling pathway
,
Phospholipase D signaling pathway
,
Endocytosis
,
PI3K-Akt signaling pathway
,
Focal adhesion
,
Adherens junction
,
Gap junction
,
JAK-STAT signaling pathway
,
Regulation of actin cytoskeleton
,
GnRH signaling pathway
,
Estrogen signaling pathway
,
Oxytocin signaling pathway
,
Relaxin signaling pathway
,
Parathyroid hormone synthesis, secretion and action
,
Cushing syndrome
,
Epithelial cell signaling in Helicobacter pylori infection
,
Shigellosis
,
Hepatitis C
,
Human cytomegalovirus infection
,
Human papillomavirus infection
,
Coronavirus disease - COVID-19
,
Pathways in cancer
,
Proteoglycans in cancer
,
MicroRNAs in cancer
,
Chemical carcinogenesis - receptor activation
,
Chemical carcinogenesis - reactive oxygen species
,
Colorectal cancer
,
Pancreatic cancer
,
Endometrial cancer
,
Glioma
,
Prostate cancer
,
Melanoma
,
Bladder cancer
,
Non-small cell lung cancer
,
Breast cancer
,
Hepatocellular carcinoma
,
Gastric cancer
,
Central carbon metabolism in cancer
,
Choline metabolism in cancer
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
48件:
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
MAPK signaling pathway
,
ErbB s
...
Gefitinib
Gefitinib
💬
10. EGFR
×
Name
Other Names
Gefitinib
Gefitinib (JP18/USAN/INN)
Iressa (TN)
ゲフィチニブ
イレッサ
Gefitinib
1件:
75
75
💬
10. EGFR
×
告示番号
日本語名
英語名
75
クッシング病
Cushing disease