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No.
KEGG GENES
KEGG PATHWAY
KEGG DRUG
DrugBank
指定難病告示番号
1
MAPK14
💬
1. MAPK14
×
Name
Full Name
MAPK14
mitogen-activated protein kinase 14
62件:
Endocrine resistance
Endocrine resistance
,
MAPK signaling pathway
,
Rap1 signaling pathway
,
FoxO signaling pathway
,
Sphingolipid signaling pathway
,
Oocyte meiosis
,
Cellular senescence
,
Adrenergic signaling in cardiomyocytes
,
VEGF signaling pathway
,
Osteoclast differentiation
,
Signaling pathways regulating pluripotency of stem cells
,
Platelet activation
,
Neutrophil extracellular trap formation
,
Toll-like receptor signaling pathway
,
NOD-like receptor signaling pathway
,
RIG-I-like receptor signaling pathway
,
C-type lectin receptor signaling pathway
,
IL-17 signaling pathway
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
T cell receptor signaling pathway
,
Fc epsilon RI signaling pathway
,
TNF signaling pathway
,
Leukocyte transendothelial migration
,
Thermogenesis
,
Neurotrophin signaling pathway
,
Retrograde endocannabinoid signaling
,
Dopaminergic synapse
,
Inflammatory mediator regulation of TRP channels
,
GnRH signaling pathway
,
Progesterone-mediated oocyte maturation
,
Prolactin signaling pathway
,
Relaxin signaling pathway
,
Non-alcoholic fatty liver disease
,
AGE-RAGE signaling pathway in diabetic complications
,
Growth hormone synthesis, secretion and action
,
Alcoholic liver disease
,
Amyotrophic lateral sclerosis
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Epithelial cell signaling in Helicobacter pylori infection
,
Pathogenic Escherichia coli infection
,
Shigellosis
,
Salmonella infection
,
Pertussis
,
Yersinia infection
,
Leishmaniasis
,
Chagas disease
,
Toxoplasmosis
,
Tuberculosis
,
Hepatitis B
,
Human cytomegalovirus infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Epstein-Barr virus infection
,
Human immunodeficiency virus 1 infection
,
Coronavirus disease - COVID-19
,
Proteoglycans in cancer
,
Chemical carcinogenesis - reactive oxygen species
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
Diabetic cardiomyopathy
,
Lipid and atherosclerosis
,
Fluid shear stress and atherosclerosis
62件:
Endocrine resistance
,
MAPK signaling pathway
,
Rap1 signaling pathway
,
FoxO signaling pathway
,
S
...
Losmapimod
Losmapimod
💬
1. MAPK14
×
Name
Other Names
Losmapimod
Losmapimod (USAN/INN)
ロスマピモド
Losmapimod
2件:
113
113
,
222
💬
1. MAPK14
×
告示番号
日本語名
英語名
113
筋ジストロフィー
Muscular dystrophy
222
一次性ネフローゼ症候群
Primary nephrotic syndrome
2
MAPK14
💬
2. MAPK14
×
Name
Full Name
MAPK14
mitogen-activated protein kinase 14
62件:
Endocrine resistance
Endocrine resistance
,
MAPK signaling pathway
,
Rap1 signaling pathway
,
FoxO signaling pathway
,
Sphingolipid signaling pathway
,
Oocyte meiosis
,
Cellular senescence
,
Adrenergic signaling in cardiomyocytes
,
VEGF signaling pathway
,
Osteoclast differentiation
,
Signaling pathways regulating pluripotency of stem cells
,
Platelet activation
,
Neutrophil extracellular trap formation
,
Toll-like receptor signaling pathway
,
NOD-like receptor signaling pathway
,
RIG-I-like receptor signaling pathway
,
C-type lectin receptor signaling pathway
,
IL-17 signaling pathway
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
T cell receptor signaling pathway
,
Fc epsilon RI signaling pathway
,
TNF signaling pathway
,
Leukocyte transendothelial migration
,
Thermogenesis
,
Neurotrophin signaling pathway
,
Retrograde endocannabinoid signaling
,
Dopaminergic synapse
,
Inflammatory mediator regulation of TRP channels
,
GnRH signaling pathway
,
Progesterone-mediated oocyte maturation
,
Prolactin signaling pathway
,
Relaxin signaling pathway
,
Non-alcoholic fatty liver disease
,
AGE-RAGE signaling pathway in diabetic complications
,
Growth hormone synthesis, secretion and action
,
Alcoholic liver disease
,
Amyotrophic lateral sclerosis
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Epithelial cell signaling in Helicobacter pylori infection
,
Pathogenic Escherichia coli infection
,
Shigellosis
,
Salmonella infection
,
Pertussis
,
Yersinia infection
,
Leishmaniasis
,
Chagas disease
,
Toxoplasmosis
,
Tuberculosis
,
Hepatitis B
,
Human cytomegalovirus infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Epstein-Barr virus infection
,
Human immunodeficiency virus 1 infection
,
Coronavirus disease - COVID-19
,
Proteoglycans in cancer
,
Chemical carcinogenesis - reactive oxygen species
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
Diabetic cardiomyopathy
,
Lipid and atherosclerosis
,
Fluid shear stress and atherosclerosis
62件:
Endocrine resistance
,
MAPK signaling pathway
,
Rap1 signaling pathway
,
FoxO signaling pathway
,
S
...
Neflamapimod
Neflamapimod
💬
2. MAPK14
×
Name
Other Names
Neflamapimod
Neflamapimod (USAN)
ネフラマピモド
Neflamapimod
1件:
8
8
💬
2. MAPK14
×
告示番号
日本語名
英語名
8
ハンチントン病
Huntington disease
3
HRH1
💬
3. HRH1
×
Name
Full Name
HRH1
histamine receptor H1
3件:
Calcium signaling pathway
Calcium signaling pathway
,
Neuroactive ligand-receptor interaction
,
Inflammatory mediator regulation of TRP channels
3件:
Calcium signaling pathway
,
Neuroactive ligand-receptor interaction
,
Inflammatory mediator regula
...
Chlorpromazine
Chlorpromazine
💬
3. HRH1
×
Name
Other Names
Chlorpromazine
Chlorpromazine (USP/INN)
Thorazine (TN)
クロルプロマジン
Chlorpromazine
1件:
254
254
💬
3. HRH1
×
告示番号
日本語名
英語名
254
ポルフィリン症
Porphyria
4
HRH1
💬
4. HRH1
×
Name
Full Name
HRH1
histamine receptor H1
3件:
Calcium signaling pathway
Calcium signaling pathway
,
Neuroactive ligand-receptor interaction
,
Inflammatory mediator regulation of TRP channels
3件:
Calcium signaling pathway
,
Neuroactive ligand-receptor interaction
,
Inflammatory mediator regula
...
Diphenhydramine
Diphenhydramine
💬
4. HRH1
×
Name
Other Names
Diphenhydramine
Diphenhydramine (JP18/INN)
Restamin (TN)
ジフェンヒドラミン
レスタミン
Diphenhydramine
8件:
11
11
,
13
,
49
,
51
,
70
,
86
,
222
,
256
💬
4. HRH1
×
告示番号
日本語名
英語名
11
重症筋無力症
Myasthenia gravis
13
多発性硬化症／視神経脊髄炎
Multiple sclerosis/Neuromyelitis optica
49
全身性エリテマトーデス
Systemic lupus erythematosus
51
全身性強皮症
Scleroderma
70
広範脊柱管狭窄症
Spinal stenosis
86
肺動脈性肺高血圧症
Pulmonary arterial hypertension
222
一次性ネフローゼ症候群
Primary nephrotic syndrome
256
筋型糖原病
Muscle glycogenosis
5
HRH1
💬
5. HRH1
×
Name
Full Name
HRH1
histamine receptor H1
3件:
Calcium signaling pathway
Calcium signaling pathway
,
Neuroactive ligand-receptor interaction
,
Inflammatory mediator regulation of TRP channels
3件:
Calcium signaling pathway
,
Neuroactive ligand-receptor interaction
,
Inflammatory mediator regula
...
Loratadine
Loratadine
💬
5. HRH1
×
Name
Other Names
Loratadine
Loratadine (JAN/USP/INN)
Claritin (TN)
ロラタジン
クラリチン
Loratadine
4件:
13
13
,
46
,
89
,
98
💬
5. HRH1
×
告示番号
日本語名
英語名
13
多発性硬化症／視神経脊髄炎
Multiple sclerosis/Neuromyelitis optica
46
悪性関節リウマチ
Malignant rheumatoid arthritis
89
リンパ脈管筋腫症
Lymphangioleiomyomatosis
98
好酸球性消化管疾患
Eosinophilic gastrointestinal disease
6
HRH1
💬
6. HRH1
×
Name
Full Name
HRH1
histamine receptor H1
3件:
Calcium signaling pathway
Calcium signaling pathway
,
Neuroactive ligand-receptor interaction
,
Inflammatory mediator regulation of TRP channels
3件:
Calcium signaling pathway
,
Neuroactive ligand-receptor interaction
,
Inflammatory mediator regula
...
Olanzapine
Olanzapine
💬
6. HRH1
×
Name
Other Names
Olanzapine
Olanzapine (JAN/USP/INN)
Zyprexa (TN)
オランザピン
ジプレキサ
Olanzapine
2件:
2
2
,
8
💬
6. HRH1
×
告示番号
日本語名
英語名
2
筋萎縮性側索硬化症
Amyotrophic lateral sclerosis
8
ハンチントン病
Huntington disease
7
HRH1
💬
7. HRH1
×
Name
Full Name
HRH1
histamine receptor H1
3件:
Calcium signaling pathway
Calcium signaling pathway
,
Neuroactive ligand-receptor interaction
,
Inflammatory mediator regulation of TRP channels
3件:
Calcium signaling pathway
,
Neuroactive ligand-receptor interaction
,
Inflammatory mediator regula
...
Promethazine
Promethazine
💬
7. HRH1
×
Name
Other Names
Promethazine
Promethazine (JAN/INN)
プロメタジン
Promethazine
1件:
96
96
💬
7. HRH1
×
告示番号
日本語名
英語名
96
クローン病;回腸末端炎
Crohn disease
8
HRH1
💬
8. HRH1
×
Name
Full Name
HRH1
histamine receptor H1
3件:
Calcium signaling pathway
Calcium signaling pathway
,
Neuroactive ligand-receptor interaction
,
Inflammatory mediator regulation of TRP channels
3件:
Calcium signaling pathway
,
Neuroactive ligand-receptor interaction
,
Inflammatory mediator regula
...
Clemastine
Clemastine
💬
8. HRH1
×
Name
Other Names
Clemastine
Clemastine (USAN)
クレマスチン
Clemastine
1件:
13
13
💬
8. HRH1
×
告示番号
日本語名
英語名
13
多発性硬化症／視神経脊髄炎
Multiple sclerosis/Neuromyelitis optica
9
HRH1
💬
9. HRH1
×
Name
Full Name
HRH1
histamine receptor H1
3件:
Calcium signaling pathway
Calcium signaling pathway
,
Neuroactive ligand-receptor interaction
,
Inflammatory mediator regulation of TRP channels
3件:
Calcium signaling pathway
,
Neuroactive ligand-receptor interaction
,
Inflammatory mediator regula
...
Desloratadine
Desloratadine
💬
9. HRH1
×
Name
Other Names
Desloratadine
Desloratadine (JAN/USP/INN)
Clarinex (TN)
デスロラタジン
デザレックス
Desloratadine
1件:
13
13
💬
9. HRH1
×
告示番号
日本語名
英語名
13
多発性硬化症／視神経脊髄炎
Multiple sclerosis/Neuromyelitis optica
10
HRH1
💬
10. HRH1
×
Name
Full Name
HRH1
histamine receptor H1
3件:
Calcium signaling pathway
Calcium signaling pathway
,
Neuroactive ligand-receptor interaction
,
Inflammatory mediator regulation of TRP channels
3件:
Calcium signaling pathway
,
Neuroactive ligand-receptor interaction
,
Inflammatory mediator regula
...
Chlorphenamine
Chlorphenamine
💬
10. HRH1
×
Name
Other Names
Chlorphenamine
Chlorphenamine (INN)
Chlorpheniramine
Clofeniramina (TN)
クロルフェナミン
クロルフェニラミン
Chlorpheniramine
1件:
14
14
💬
10. HRH1
×
告示番号
日本語名
英語名
14
慢性炎症性脱髄性多発神経炎／多巣性運動ニューロパチー
Chronic inflammatory demyelinating polyneuropathy