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No.
KEGG GENES
KEGG PATHWAY
KEGG DRUG
DrugBank
指定難病告示番号
1
EGFR
💬
1. EGFR
×
Name
Full Name
EGFR
epidermal growth factor receptor
48件:
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
MAPK signaling pathway
,
ErbB signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Calcium signaling pathway
,
HIF-1 signaling pathway
,
FoxO signaling pathway
,
Phospholipase D signaling pathway
,
Endocytosis
,
PI3K-Akt signaling pathway
,
Focal adhesion
,
Adherens junction
,
Gap junction
,
JAK-STAT signaling pathway
,
Regulation of actin cytoskeleton
,
GnRH signaling pathway
,
Estrogen signaling pathway
,
Oxytocin signaling pathway
,
Relaxin signaling pathway
,
Parathyroid hormone synthesis, secretion and action
,
Cushing syndrome
,
Epithelial cell signaling in Helicobacter pylori infection
,
Shigellosis
,
Hepatitis C
,
Human cytomegalovirus infection
,
Human papillomavirus infection
,
Coronavirus disease - COVID-19
,
Pathways in cancer
,
Proteoglycans in cancer
,
MicroRNAs in cancer
,
Chemical carcinogenesis - receptor activation
,
Chemical carcinogenesis - reactive oxygen species
,
Colorectal cancer
,
Pancreatic cancer
,
Endometrial cancer
,
Glioma
,
Prostate cancer
,
Melanoma
,
Bladder cancer
,
Non-small cell lung cancer
,
Breast cancer
,
Hepatocellular carcinoma
,
Gastric cancer
,
Central carbon metabolism in cancer
,
Choline metabolism in cancer
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
48件:
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
MAPK signaling pathway
,
ErbB s
...
Gefitinib
Gefitinib
💬
1. EGFR
×
Name
Other Names
Gefitinib
Gefitinib (JP18/USAN/INN)
Iressa (TN)
ゲフィチニブ
イレッサ
Gefitinib
1件:
75
75
💬
1. EGFR
×
告示番号
日本語名
英語名
75
クッシング病
Cushing disease
2
EGFR
💬
2. EGFR
×
Name
Full Name
EGFR
epidermal growth factor receptor
48件:
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
MAPK signaling pathway
,
ErbB signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Calcium signaling pathway
,
HIF-1 signaling pathway
,
FoxO signaling pathway
,
Phospholipase D signaling pathway
,
Endocytosis
,
PI3K-Akt signaling pathway
,
Focal adhesion
,
Adherens junction
,
Gap junction
,
JAK-STAT signaling pathway
,
Regulation of actin cytoskeleton
,
GnRH signaling pathway
,
Estrogen signaling pathway
,
Oxytocin signaling pathway
,
Relaxin signaling pathway
,
Parathyroid hormone synthesis, secretion and action
,
Cushing syndrome
,
Epithelial cell signaling in Helicobacter pylori infection
,
Shigellosis
,
Hepatitis C
,
Human cytomegalovirus infection
,
Human papillomavirus infection
,
Coronavirus disease - COVID-19
,
Pathways in cancer
,
Proteoglycans in cancer
,
MicroRNAs in cancer
,
Chemical carcinogenesis - receptor activation
,
Chemical carcinogenesis - reactive oxygen species
,
Colorectal cancer
,
Pancreatic cancer
,
Endometrial cancer
,
Glioma
,
Prostate cancer
,
Melanoma
,
Bladder cancer
,
Non-small cell lung cancer
,
Breast cancer
,
Hepatocellular carcinoma
,
Gastric cancer
,
Central carbon metabolism in cancer
,
Choline metabolism in cancer
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
48件:
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
MAPK signaling pathway
,
ErbB s
...
Cetuximab
Cetuximab
💬
2. EGFR
×
Name
Other Names
Cetuximab
Cetuximab (USAN/INN)
Cetuximab (genetical recombination) (JAN)
Erbitux (TN)
セツキシマブ
アービタックス
Cetuximab
2件:
51
51
,
86
💬
2. EGFR
×
告示番号
日本語名
英語名
51
全身性強皮症
Scleroderma
86
肺動脈性肺高血圧症
Pulmonary arterial hypertension
3
EGFR
💬
3. EGFR
×
Name
Full Name
EGFR
epidermal growth factor receptor
48件:
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
MAPK signaling pathway
,
ErbB signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Calcium signaling pathway
,
HIF-1 signaling pathway
,
FoxO signaling pathway
,
Phospholipase D signaling pathway
,
Endocytosis
,
PI3K-Akt signaling pathway
,
Focal adhesion
,
Adherens junction
,
Gap junction
,
JAK-STAT signaling pathway
,
Regulation of actin cytoskeleton
,
GnRH signaling pathway
,
Estrogen signaling pathway
,
Oxytocin signaling pathway
,
Relaxin signaling pathway
,
Parathyroid hormone synthesis, secretion and action
,
Cushing syndrome
,
Epithelial cell signaling in Helicobacter pylori infection
,
Shigellosis
,
Hepatitis C
,
Human cytomegalovirus infection
,
Human papillomavirus infection
,
Coronavirus disease - COVID-19
,
Pathways in cancer
,
Proteoglycans in cancer
,
MicroRNAs in cancer
,
Chemical carcinogenesis - receptor activation
,
Chemical carcinogenesis - reactive oxygen species
,
Colorectal cancer
,
Pancreatic cancer
,
Endometrial cancer
,
Glioma
,
Prostate cancer
,
Melanoma
,
Bladder cancer
,
Non-small cell lung cancer
,
Breast cancer
,
Hepatocellular carcinoma
,
Gastric cancer
,
Central carbon metabolism in cancer
,
Choline metabolism in cancer
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
48件:
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
MAPK signaling pathway
,
ErbB s
...
Erlotinib
Erlotinib
💬
3. EGFR
×
Name
Other Names
Erlotinib
Erlotinib (INN)
エルロチニブ
Erlotinib
1件:
94
94
💬
3. EGFR
×
告示番号
日本語名
英語名
94
原発性硬化性胆管炎
Primary sclerosing cholangitis
4
EGFR
💬
4. EGFR
×
Name
Full Name
EGFR
epidermal growth factor receptor
48件:
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
MAPK signaling pathway
,
ErbB signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Calcium signaling pathway
,
HIF-1 signaling pathway
,
FoxO signaling pathway
,
Phospholipase D signaling pathway
,
Endocytosis
,
PI3K-Akt signaling pathway
,
Focal adhesion
,
Adherens junction
,
Gap junction
,
JAK-STAT signaling pathway
,
Regulation of actin cytoskeleton
,
GnRH signaling pathway
,
Estrogen signaling pathway
,
Oxytocin signaling pathway
,
Relaxin signaling pathway
,
Parathyroid hormone synthesis, secretion and action
,
Cushing syndrome
,
Epithelial cell signaling in Helicobacter pylori infection
,
Shigellosis
,
Hepatitis C
,
Human cytomegalovirus infection
,
Human papillomavirus infection
,
Coronavirus disease - COVID-19
,
Pathways in cancer
,
Proteoglycans in cancer
,
MicroRNAs in cancer
,
Chemical carcinogenesis - receptor activation
,
Chemical carcinogenesis - reactive oxygen species
,
Colorectal cancer
,
Pancreatic cancer
,
Endometrial cancer
,
Glioma
,
Prostate cancer
,
Melanoma
,
Bladder cancer
,
Non-small cell lung cancer
,
Breast cancer
,
Hepatocellular carcinoma
,
Gastric cancer
,
Central carbon metabolism in cancer
,
Choline metabolism in cancer
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
48件:
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
MAPK signaling pathway
,
ErbB s
...
Lapatinib
Lapatinib
💬
4. EGFR
×
Name
Other Names
Lapatinib
Lapatinib (INN)
ラパチニブ
Lapatinib
3件:
34
34
,
74
,
75
💬
4. EGFR
×
告示番号
日本語名
英語名
34
神経線維腫症
Neurofibromatosis
74
下垂体性PRL分泌亢進症
Prolactin secreting pituitary adenoma
75
クッシング病
Cushing disease
5
EGFR
💬
5. EGFR
×
Name
Full Name
EGFR
epidermal growth factor receptor
48件:
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
MAPK signaling pathway
,
ErbB signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Calcium signaling pathway
,
HIF-1 signaling pathway
,
FoxO signaling pathway
,
Phospholipase D signaling pathway
,
Endocytosis
,
PI3K-Akt signaling pathway
,
Focal adhesion
,
Adherens junction
,
Gap junction
,
JAK-STAT signaling pathway
,
Regulation of actin cytoskeleton
,
GnRH signaling pathway
,
Estrogen signaling pathway
,
Oxytocin signaling pathway
,
Relaxin signaling pathway
,
Parathyroid hormone synthesis, secretion and action
,
Cushing syndrome
,
Epithelial cell signaling in Helicobacter pylori infection
,
Shigellosis
,
Hepatitis C
,
Human cytomegalovirus infection
,
Human papillomavirus infection
,
Coronavirus disease - COVID-19
,
Pathways in cancer
,
Proteoglycans in cancer
,
MicroRNAs in cancer
,
Chemical carcinogenesis - receptor activation
,
Chemical carcinogenesis - reactive oxygen species
,
Colorectal cancer
,
Pancreatic cancer
,
Endometrial cancer
,
Glioma
,
Prostate cancer
,
Melanoma
,
Bladder cancer
,
Non-small cell lung cancer
,
Breast cancer
,
Hepatocellular carcinoma
,
Gastric cancer
,
Central carbon metabolism in cancer
,
Choline metabolism in cancer
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
48件:
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
MAPK signaling pathway
,
ErbB s
...
Neratinib
Neratinib
💬
5. EGFR
×
Name
Other Names
Neratinib
Neratinib (USAN/INN)
ネラチニブ
Neratinib
1件:
34
34
💬
5. EGFR
×
告示番号
日本語名
英語名
34
神経線維腫症
Neurofibromatosis
6
EGFR
💬
6. EGFR
×
Name
Full Name
EGFR
epidermal growth factor receptor
48件:
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
MAPK signaling pathway
,
ErbB signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Calcium signaling pathway
,
HIF-1 signaling pathway
,
FoxO signaling pathway
,
Phospholipase D signaling pathway
,
Endocytosis
,
PI3K-Akt signaling pathway
,
Focal adhesion
,
Adherens junction
,
Gap junction
,
JAK-STAT signaling pathway
,
Regulation of actin cytoskeleton
,
GnRH signaling pathway
,
Estrogen signaling pathway
,
Oxytocin signaling pathway
,
Relaxin signaling pathway
,
Parathyroid hormone synthesis, secretion and action
,
Cushing syndrome
,
Epithelial cell signaling in Helicobacter pylori infection
,
Shigellosis
,
Hepatitis C
,
Human cytomegalovirus infection
,
Human papillomavirus infection
,
Coronavirus disease - COVID-19
,
Pathways in cancer
,
Proteoglycans in cancer
,
MicroRNAs in cancer
,
Chemical carcinogenesis - receptor activation
,
Chemical carcinogenesis - reactive oxygen species
,
Colorectal cancer
,
Pancreatic cancer
,
Endometrial cancer
,
Glioma
,
Prostate cancer
,
Melanoma
,
Bladder cancer
,
Non-small cell lung cancer
,
Breast cancer
,
Hepatocellular carcinoma
,
Gastric cancer
,
Central carbon metabolism in cancer
,
Choline metabolism in cancer
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
48件:
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
MAPK signaling pathway
,
ErbB s
...
Icotinib
Icotinib
💬
6. EGFR
×
Name
Other Names
Icotinib
Icotinib
イコチニブ
Icotinib
1件:
34
34
💬
6. EGFR
×
告示番号
日本語名
英語名
34
神経線維腫症
Neurofibromatosis
7
EGFR
💬
7. EGFR
×
Name
Full Name
EGFR
epidermal growth factor receptor
48件:
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
MAPK signaling pathway
,
ErbB signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Calcium signaling pathway
,
HIF-1 signaling pathway
,
FoxO signaling pathway
,
Phospholipase D signaling pathway
,
Endocytosis
,
PI3K-Akt signaling pathway
,
Focal adhesion
,
Adherens junction
,
Gap junction
,
JAK-STAT signaling pathway
,
Regulation of actin cytoskeleton
,
GnRH signaling pathway
,
Estrogen signaling pathway
,
Oxytocin signaling pathway
,
Relaxin signaling pathway
,
Parathyroid hormone synthesis, secretion and action
,
Cushing syndrome
,
Epithelial cell signaling in Helicobacter pylori infection
,
Shigellosis
,
Hepatitis C
,
Human cytomegalovirus infection
,
Human papillomavirus infection
,
Coronavirus disease - COVID-19
,
Pathways in cancer
,
Proteoglycans in cancer
,
MicroRNAs in cancer
,
Chemical carcinogenesis - receptor activation
,
Chemical carcinogenesis - reactive oxygen species
,
Colorectal cancer
,
Pancreatic cancer
,
Endometrial cancer
,
Glioma
,
Prostate cancer
,
Melanoma
,
Bladder cancer
,
Non-small cell lung cancer
,
Breast cancer
,
Hepatocellular carcinoma
,
Gastric cancer
,
Central carbon metabolism in cancer
,
Choline metabolism in cancer
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
48件:
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
MAPK signaling pathway
,
ErbB s
...
Tesevatinib
Tesevatinib
💬
7. EGFR
×
Name
Other Names
Tesevatinib
Tesevatinib (USAN/INN)
テセバチニブ
Tesevatinib
1件:
67
67
💬
7. EGFR
×
告示番号
日本語名
英語名
67
多発性嚢胞腎
Polycystic kidney disease
8
GUCY1A2
💬
8. GUCY1A2
×
Name
Full Name
GUCY1A2
guanylate cyclase 1 soluble subunit alpha 2
11件:
Purine metabolism
Purine metabolism
,
Metabolic pathways
,
cGMP-PKG signaling pathway
,
Vascular smooth muscle contraction
,
Gap junction
,
Platelet activation
,
Circadian entrainment
,
Long-term depression
,
Oxytocin signaling pathway
,
Renin secretion
,
Salivary secretion
11件:
Purine metabolism
,
Metabolic pathways
,
cGMP-PKG signaling pathway
,
Vascular smooth muscle contr
...
Amyl nitrite
Amyl nitrite
💬
8. GUCY1A2
×
Name
Other Names
Amyl nitrite
Amyl nitrite (JP18/USP)
Aspiral (TN)
Vaporole (TN)
亜硝酸アミル
Amyl Nitrite
1件:
58
58
💬
8. GUCY1A2
×
告示番号
日本語名
英語名
58
肥大型心筋症
Hypertrophic cardiomyopathy
9
GUCY1A2
💬
9. GUCY1A2
×
Name
Full Name
GUCY1A2
guanylate cyclase 1 soluble subunit alpha 2
11件:
Purine metabolism
Purine metabolism
,
Metabolic pathways
,
cGMP-PKG signaling pathway
,
Vascular smooth muscle contraction
,
Gap junction
,
Platelet activation
,
Circadian entrainment
,
Long-term depression
,
Oxytocin signaling pathway
,
Renin secretion
,
Salivary secretion
11件:
Purine metabolism
,
Metabolic pathways
,
cGMP-PKG signaling pathway
,
Vascular smooth muscle contr
...
Riociguat
Riociguat
💬
9. GUCY1A2
×
Name
Other Names
Riociguat
Riociguat (JAN/USAN/INN)
Adempas (TN)
リオシグアト
アデムパス
Riociguat
6件:
51
51
,
84
,
86
,
88
,
225
,
299
💬
9. GUCY1A2
×
告示番号
日本語名
英語名
51
全身性強皮症
Scleroderma
84
サルコイドーシス
Sarcoidosis
86
肺動脈性肺高血圧症
Pulmonary arterial hypertension
88
慢性血栓塞栓性肺高血圧症;特発性慢性肺血栓塞栓症（肺高血圧型）
Chronic thromboembolic pulmonary hypertension
225
先天性腎性尿崩症;遺伝性腎性尿崩症
Congenital nephrogenic diabetes insipidus
299
嚢胞性線維症;膵囊胞線維症
Cystic fibrosis
10
GUCY1A1
💬
10. GUCY1A1
×
Name
Full Name
GUCY1A1
guanylate cyclase 1 soluble subunit alpha 1
11件:
Purine metabolism
Purine metabolism
,
Metabolic pathways
,
cGMP-PKG signaling pathway
,
Vascular smooth muscle contraction
,
Gap junction
,
Platelet activation
,
Circadian entrainment
,
Long-term depression
,
Oxytocin signaling pathway
,
Renin secretion
,
Salivary secretion
11件:
Purine metabolism
,
Metabolic pathways
,
cGMP-PKG signaling pathway
,
Vascular smooth muscle contr
...
Amyl nitrite
Amyl nitrite
💬
10. GUCY1A1
×
Name
Other Names
Amyl nitrite
Amyl nitrite (JP18/USP)
Aspiral (TN)
Vaporole (TN)
亜硝酸アミル
Amyl Nitrite
1件:
58
58
💬
10. GUCY1A1
×
告示番号
日本語名
英語名
58
肥大型心筋症
Hypertrophic cardiomyopathy