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No.
KEGG GENES
KEGG PATHWAY
KEGG DRUG
DrugBank
指定難病告示番号
1
HDAC5
💬
1. HDAC5
×
Name
Full Name
HDAC5
histone deacetylase 5
5件:
Apelin signaling pathway
Apelin signaling pathway
,
Neutrophil extracellular trap formation
,
Alcoholism
,
Viral carcinogenesis
,
MicroRNAs in cancer
5件:
Apelin signaling pathway
,
Neutrophil extracellular trap formation
,
Alcoholism
,
Viral carcinogene
...
Vorinostat
Vorinostat
💬
1. HDAC5
×
Name
Other Names
Vorinostat
Vorinostat (JAN/USAN)
Zolinza (TN)
ボリノスタット
ゾリンザ
Vorinostat
2件:
75
75
,
96
💬
1. HDAC5
×
告示番号
日本語名
英語名
75
クッシング病
Cushing disease
96
クローン病;回腸末端炎
Crohn disease
2
CDK6
💬
2. CDK6
×
Name
Full Name
CDK6
cyclin dependent kinase 6
23件:
Cell cycle
Cell cycle
,
p53 signaling pathway
,
PI3K-Akt signaling pathway
,
Cellular senescence
,
Cushing syndrome
,
Hepatitis C
,
Measles
,
Human cytomegalovirus infection
,
Influenza A
,
Human papillomavirus infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Epstein-Barr virus infection
,
Pathways in cancer
,
Viral carcinogenesis
,
MicroRNAs in cancer
,
Pancreatic cancer
,
Glioma
,
Melanoma
,
Chronic myeloid leukemia
,
Small cell lung cancer
,
Non-small cell lung cancer
,
Breast cancer
,
Hepatocellular carcinoma
23件:
Cell cycle
,
p53 signaling pathway
,
PI3K-Akt signaling pathway
,
Cellular senescence
,
Cushing syn
...
Abemaciclib
Abemaciclib
💬
2. CDK6
×
Name
Other Names
Abemaciclib
Abemaciclib (JAN/USAN)
Verzenio (TN)
アベマシクリブ
ベージニオ
Abemaciclib
1件:
34
34
💬
2. CDK6
×
告示番号
日本語名
英語名
34
神経線維腫症
Neurofibromatosis
3
DNMT1
💬
3. DNMT1
×
Name
Full Name
DNMT1
DNA methyltransferase 1
3件:
Cysteine and methionine metabolism
Cysteine and methionine metabolism
,
Metabolic pathways
,
MicroRNAs in cancer
Decitabine
Decitabine
💬
3. DNMT1
×
Name
Other Names
Decitabine
Decitabine (USAN/INN)
Dacogen (TN)
デシタビン
Decitabine
3件:
13
13
,
60
,
63
💬
3. DNMT1
×
告示番号
日本語名
英語名
13
多発性硬化症／視神経脊髄炎
Multiple sclerosis/Neuromyelitis optica
60
再生不良性貧血
Aplastic anemia
63
特発性血小板減少性紫斑病;一次性免疫性血小板減少症
Idiopathic thrombocytopenic purpura
4
DNMT3A
💬
4. DNMT3A
×
Name
Full Name
DNMT3A
DNA methyltransferase 3 alpha
3件:
Cysteine and methionine metabolism
Cysteine and methionine metabolism
,
Metabolic pathways
,
MicroRNAs in cancer
Decitabine
Decitabine
💬
4. DNMT3A
×
Name
Other Names
Decitabine
Decitabine (USAN/INN)
Dacogen (TN)
デシタビン
Decitabine
3件:
13
13
,
60
,
63
💬
4. DNMT3A
×
告示番号
日本語名
英語名
13
多発性硬化症／視神経脊髄炎
Multiple sclerosis/Neuromyelitis optica
60
再生不良性貧血
Aplastic anemia
63
特発性血小板減少性紫斑病;一次性免疫性血小板減少症
Idiopathic thrombocytopenic purpura
5
DNMT3B
💬
5. DNMT3B
×
Name
Full Name
DNMT3B
DNA methyltransferase 3 beta
3件:
Cysteine and methionine metabolism
Cysteine and methionine metabolism
,
Metabolic pathways
,
MicroRNAs in cancer
Decitabine
Decitabine
💬
5. DNMT3B
×
Name
Other Names
Decitabine
Decitabine (USAN/INN)
Dacogen (TN)
デシタビン
Decitabine
3件:
13
13
,
60
,
63
💬
5. DNMT3B
×
告示番号
日本語名
英語名
13
多発性硬化症／視神経脊髄炎
Multiple sclerosis/Neuromyelitis optica
60
再生不良性貧血
Aplastic anemia
63
特発性血小板減少性紫斑病;一次性免疫性血小板減少症
Idiopathic thrombocytopenic purpura
6
EGFR
💬
6. EGFR
×
Name
Full Name
EGFR
epidermal growth factor receptor
48件:
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
MAPK signaling pathway
,
ErbB signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Calcium signaling pathway
,
HIF-1 signaling pathway
,
FoxO signaling pathway
,
Phospholipase D signaling pathway
,
Endocytosis
,
PI3K-Akt signaling pathway
,
Focal adhesion
,
Adherens junction
,
Gap junction
,
JAK-STAT signaling pathway
,
Regulation of actin cytoskeleton
,
GnRH signaling pathway
,
Estrogen signaling pathway
,
Oxytocin signaling pathway
,
Relaxin signaling pathway
,
Parathyroid hormone synthesis, secretion and action
,
Cushing syndrome
,
Epithelial cell signaling in Helicobacter pylori infection
,
Shigellosis
,
Hepatitis C
,
Human cytomegalovirus infection
,
Human papillomavirus infection
,
Coronavirus disease - COVID-19
,
Pathways in cancer
,
Proteoglycans in cancer
,
MicroRNAs in cancer
,
Chemical carcinogenesis - receptor activation
,
Chemical carcinogenesis - reactive oxygen species
,
Colorectal cancer
,
Pancreatic cancer
,
Endometrial cancer
,
Glioma
,
Prostate cancer
,
Melanoma
,
Bladder cancer
,
Non-small cell lung cancer
,
Breast cancer
,
Hepatocellular carcinoma
,
Gastric cancer
,
Central carbon metabolism in cancer
,
Choline metabolism in cancer
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
48件:
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
MAPK signaling pathway
,
ErbB s
...
Gefitinib
Gefitinib
💬
6. EGFR
×
Name
Other Names
Gefitinib
Gefitinib (JP18/USAN/INN)
Iressa (TN)
ゲフィチニブ
イレッサ
Gefitinib
1件:
75
75
💬
6. EGFR
×
告示番号
日本語名
英語名
75
クッシング病
Cushing disease
7
EGFR
💬
7. EGFR
×
Name
Full Name
EGFR
epidermal growth factor receptor
48件:
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
MAPK signaling pathway
,
ErbB signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Calcium signaling pathway
,
HIF-1 signaling pathway
,
FoxO signaling pathway
,
Phospholipase D signaling pathway
,
Endocytosis
,
PI3K-Akt signaling pathway
,
Focal adhesion
,
Adherens junction
,
Gap junction
,
JAK-STAT signaling pathway
,
Regulation of actin cytoskeleton
,
GnRH signaling pathway
,
Estrogen signaling pathway
,
Oxytocin signaling pathway
,
Relaxin signaling pathway
,
Parathyroid hormone synthesis, secretion and action
,
Cushing syndrome
,
Epithelial cell signaling in Helicobacter pylori infection
,
Shigellosis
,
Hepatitis C
,
Human cytomegalovirus infection
,
Human papillomavirus infection
,
Coronavirus disease - COVID-19
,
Pathways in cancer
,
Proteoglycans in cancer
,
MicroRNAs in cancer
,
Chemical carcinogenesis - receptor activation
,
Chemical carcinogenesis - reactive oxygen species
,
Colorectal cancer
,
Pancreatic cancer
,
Endometrial cancer
,
Glioma
,
Prostate cancer
,
Melanoma
,
Bladder cancer
,
Non-small cell lung cancer
,
Breast cancer
,
Hepatocellular carcinoma
,
Gastric cancer
,
Central carbon metabolism in cancer
,
Choline metabolism in cancer
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
48件:
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
MAPK signaling pathway
,
ErbB s
...
Cetuximab
Cetuximab
💬
7. EGFR
×
Name
Other Names
Cetuximab
Cetuximab (USAN/INN)
Cetuximab (genetical recombination) (JAN)
Erbitux (TN)
セツキシマブ
アービタックス
Cetuximab
2件:
51
51
,
86
💬
7. EGFR
×
告示番号
日本語名
英語名
51
全身性強皮症
Scleroderma
86
肺動脈性肺高血圧症
Pulmonary arterial hypertension
8
EGFR
💬
8. EGFR
×
Name
Full Name
EGFR
epidermal growth factor receptor
48件:
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
MAPK signaling pathway
,
ErbB signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Calcium signaling pathway
,
HIF-1 signaling pathway
,
FoxO signaling pathway
,
Phospholipase D signaling pathway
,
Endocytosis
,
PI3K-Akt signaling pathway
,
Focal adhesion
,
Adherens junction
,
Gap junction
,
JAK-STAT signaling pathway
,
Regulation of actin cytoskeleton
,
GnRH signaling pathway
,
Estrogen signaling pathway
,
Oxytocin signaling pathway
,
Relaxin signaling pathway
,
Parathyroid hormone synthesis, secretion and action
,
Cushing syndrome
,
Epithelial cell signaling in Helicobacter pylori infection
,
Shigellosis
,
Hepatitis C
,
Human cytomegalovirus infection
,
Human papillomavirus infection
,
Coronavirus disease - COVID-19
,
Pathways in cancer
,
Proteoglycans in cancer
,
MicroRNAs in cancer
,
Chemical carcinogenesis - receptor activation
,
Chemical carcinogenesis - reactive oxygen species
,
Colorectal cancer
,
Pancreatic cancer
,
Endometrial cancer
,
Glioma
,
Prostate cancer
,
Melanoma
,
Bladder cancer
,
Non-small cell lung cancer
,
Breast cancer
,
Hepatocellular carcinoma
,
Gastric cancer
,
Central carbon metabolism in cancer
,
Choline metabolism in cancer
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
48件:
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
MAPK signaling pathway
,
ErbB s
...
Erlotinib
Erlotinib
💬
8. EGFR
×
Name
Other Names
Erlotinib
Erlotinib (INN)
エルロチニブ
Erlotinib
1件:
94
94
💬
8. EGFR
×
告示番号
日本語名
英語名
94
原発性硬化性胆管炎
Primary sclerosing cholangitis
9
EGFR
💬
9. EGFR
×
Name
Full Name
EGFR
epidermal growth factor receptor
48件:
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
MAPK signaling pathway
,
ErbB signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Calcium signaling pathway
,
HIF-1 signaling pathway
,
FoxO signaling pathway
,
Phospholipase D signaling pathway
,
Endocytosis
,
PI3K-Akt signaling pathway
,
Focal adhesion
,
Adherens junction
,
Gap junction
,
JAK-STAT signaling pathway
,
Regulation of actin cytoskeleton
,
GnRH signaling pathway
,
Estrogen signaling pathway
,
Oxytocin signaling pathway
,
Relaxin signaling pathway
,
Parathyroid hormone synthesis, secretion and action
,
Cushing syndrome
,
Epithelial cell signaling in Helicobacter pylori infection
,
Shigellosis
,
Hepatitis C
,
Human cytomegalovirus infection
,
Human papillomavirus infection
,
Coronavirus disease - COVID-19
,
Pathways in cancer
,
Proteoglycans in cancer
,
MicroRNAs in cancer
,
Chemical carcinogenesis - receptor activation
,
Chemical carcinogenesis - reactive oxygen species
,
Colorectal cancer
,
Pancreatic cancer
,
Endometrial cancer
,
Glioma
,
Prostate cancer
,
Melanoma
,
Bladder cancer
,
Non-small cell lung cancer
,
Breast cancer
,
Hepatocellular carcinoma
,
Gastric cancer
,
Central carbon metabolism in cancer
,
Choline metabolism in cancer
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
48件:
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
MAPK signaling pathway
,
ErbB s
...
Lapatinib
Lapatinib
💬
9. EGFR
×
Name
Other Names
Lapatinib
Lapatinib (INN)
ラパチニブ
Lapatinib
3件:
34
34
,
74
,
75
💬
9. EGFR
×
告示番号
日本語名
英語名
34
神経線維腫症
Neurofibromatosis
74
下垂体性PRL分泌亢進症
Prolactin secreting pituitary adenoma
75
クッシング病
Cushing disease
10
EGFR
💬
10. EGFR
×
Name
Full Name
EGFR
epidermal growth factor receptor
48件:
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
MAPK signaling pathway
,
ErbB signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Calcium signaling pathway
,
HIF-1 signaling pathway
,
FoxO signaling pathway
,
Phospholipase D signaling pathway
,
Endocytosis
,
PI3K-Akt signaling pathway
,
Focal adhesion
,
Adherens junction
,
Gap junction
,
JAK-STAT signaling pathway
,
Regulation of actin cytoskeleton
,
GnRH signaling pathway
,
Estrogen signaling pathway
,
Oxytocin signaling pathway
,
Relaxin signaling pathway
,
Parathyroid hormone synthesis, secretion and action
,
Cushing syndrome
,
Epithelial cell signaling in Helicobacter pylori infection
,
Shigellosis
,
Hepatitis C
,
Human cytomegalovirus infection
,
Human papillomavirus infection
,
Coronavirus disease - COVID-19
,
Pathways in cancer
,
Proteoglycans in cancer
,
MicroRNAs in cancer
,
Chemical carcinogenesis - receptor activation
,
Chemical carcinogenesis - reactive oxygen species
,
Colorectal cancer
,
Pancreatic cancer
,
Endometrial cancer
,
Glioma
,
Prostate cancer
,
Melanoma
,
Bladder cancer
,
Non-small cell lung cancer
,
Breast cancer
,
Hepatocellular carcinoma
,
Gastric cancer
,
Central carbon metabolism in cancer
,
Choline metabolism in cancer
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
48件:
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
MAPK signaling pathway
,
ErbB s
...
Neratinib
Neratinib
💬
10. EGFR
×
Name
Other Names
Neratinib
Neratinib (USAN/INN)
ネラチニブ
Neratinib
1件:
34
34
💬
10. EGFR
×
告示番号
日本語名
英語名
34
神経線維腫症
Neurofibromatosis