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KEGG GENES

KEGG PATHWAY

KEGG DRUG

DrugBank

Disease ID

F8 💬

[1] Complement and coagulation cascades

Desmopressin 💬

Desmopressin

[6] 6, 64, 72, 75, 225, 288 💬

Disease ID	Name
6	Parkinson disease
64	Thrombotic thrombocytopenic purpura
72	Pituitary ADH secretion disorder
75	Cushing disease
225	Congenital nephrogenic diabetes insipidus
288	Autoimmune acquired coagulation factor deficiency

F9 💬

[1] Complement and coagulation cascades

Emicizumab 💬

Emicizumab

[1] 288 💬

F10 💬

[1] Complement and coagulation cascades

Emicizumab 💬

Emicizumab

[1] 288 💬

NR3C1 💬

[1] Neuroactive ligand-receptor interaction

Prednisone 💬

Prednisone

[45] 2, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, ...

Disease ID	Name
2	Amyotrophic lateral sclerosis
11	Myasthenia gravis
13	Multiple sclerosis/Neuromyelitis optica
14	Chronic inflammatory demyelinating polyneuropathy
19	Lysosomal storage disease
26	HTLV-1-associated myelopathy
35	Pemphigus
40	Takayasu arteritis
41	Giant cell arteritis
42	Polyarteritis nodosa
43	Microscopic polyangiitis
44	Wegener granulomatosis
45	Eosinophilic granulomatosis with Polyangiitis
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
50	Dermatomyositis
51	Scleroderma
53	Sjogren syndrome
61	Autoimmune hemolytic anemia
63	Idiopathic thrombocytopenic purpura
64	Thrombotic thrombocytopenic purpura
65	Primary immunodeficiency
66	IgA nephropathy
79	Homozygous familial hypercholesterolemia
81	Congenital adrenal hyperplasia
84	Sarcoidosis
85	Idiopathic interstitial pneumonia
86	Pulmonary arterial hypertension
95	Autoimmune hepatitis
96	Crohn disease
97	Ulcerative colitis
113	Muscular dystrophy
162	Pemphigoid
164	Oculocutaneous albinism
205	Fragile X syndrome related disease
222	Primary nephrotic syndrome
224	Purpura nephritis
228	Bronchiolitis obliterans
283	Acquired pure red cell aplasia
284	Diamond-Blackfan anemia
288	Autoimmune acquired coagulation factor deficiency
299	Cystic fibrosis
300	IgG4-related disease
307	Canavan disease
331	Idiopathic multicentric castleman disease

HMGCR 💬

[4] Terpenoid backbone biosynthesis, Metabolic pathways, AMPK signaling pathway, Bile secretion

Simvastatin 💬

Simvastatin

[21] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬

Disease ID	Name
6	Parkinson disease
13	Multiple sclerosis/Neuromyelitis optica
15	Inclusion body myositis
34	Neurofibromatosis
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
51	Scleroderma
66	IgA nephropathy
79	Homozygous familial hypercholesterolemia
86	Pulmonary arterial hypertension
89	Lymphangioleiomyomatosis
94	Primary sclerosing cholangitis
158	Tuberous sclerosis
160	Congenital ichthyosis
162	Pemphigoid
195	Noonan syndrome
265	Lipodystrophy
288	Autoimmune acquired coagulation factor deficiency
298	Hereditary pancreatitis
299	Cystic fibrosis
310	Congenital anomalies syndrome

IL11RA 💬

[3] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, Hematopoietic cell lineage

Oprelvekin 💬

Oprelvekin

[2] 96, 288 💬

PLG 💬

[4] Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Staphylococcus aur ...

Tranexamic acid 💬

Tranexamic acid

[7] 46, 70, 215, 227, 274, 288, 299 💬

AVPR2 💬

[3] Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Vasopressin-regulate ...

Desmopressin 💬

Desmopressin

[6] 6, 64, 72, 75, 225, 288 💬

Disease ID	Name
6	Parkinson disease
64	Thrombotic thrombocytopenic purpura
72	Pituitary ADH secretion disorder
75	Cushing disease
225	Congenital nephrogenic diabetes insipidus
288	Autoimmune acquired coagulation factor deficiency

PSMB5 💬

[8] Proteasome, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington dise ...

Bortezomib 💬

Bortezomib

[17] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬

Disease ID	Name
11	Myasthenia gravis
13	Multiple sclerosis/Neuromyelitis optica
26	HTLV-1-associated myelopathy
28	Systemic amyloidosis
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
51	Scleroderma
61	Autoimmune hemolytic anemia
63	Idiopathic thrombocytopenic purpura
64	Thrombotic thrombocytopenic purpura
66	IgA nephropathy
222	Primary nephrotic syndrome
228	Bronchiolitis obliterans
256	Muscle glycogenosis
283	Acquired pure red cell aplasia
288	Autoimmune acquired coagulation factor deficiency
331	Idiopathic multicentric castleman disease

MS4A1 💬

[1] Hematopoietic cell lineage

Rituximab 💬

Name	Other Names
Rituximab	Rituximab (USAN/INN) Rituximab (genetical recombination) (JAN) Rituximab (genetical recombination) [Rituximab biosimilar 1] (JAN) Rituximab (genetical recombination) [Rituximab biosimilar 2] (JAN) Rituximab-abbs Rituximab-pvvr Rituximab-arrx Rituxan (TN) Riabni (TN) Truximab (TN) RUXIENCE TRUXIMA

Rituximab

[48] 11, 13, 14, 19, 26, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, ...

Disease ID	Name
11	Myasthenia gravis
13	Multiple sclerosis/Neuromyelitis optica
14	Chronic inflammatory demyelinating polyneuropathy
19	Lysosomal storage disease
26	HTLV-1-associated myelopathy
35	Pemphigus
36	Epidermolysis bullosa
40	Takayasu arteritis
41	Giant cell arteritis
42	Polyarteritis nodosa
43	Microscopic polyangiitis
44	Wegener granulomatosis
45	Eosinophilic granulomatosis with Polyangiitis
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
50	Dermatomyositis
51	Scleroderma
52	Mixed connective tissue disease
53	Sjogren syndrome
55	Relapsing polychondritis
56	Behcet disease
60	Aplastic anemia
61	Autoimmune hemolytic anemia
63	Idiopathic thrombocytopenic purpura
64	Thrombotic thrombocytopenic purpura
65	Primary immunodeficiency
66	IgA nephropathy
83	Addison disease
84	Sarcoidosis
85	Idiopathic interstitial pneumonia
86	Pulmonary arterial hypertension
93	Primary biliary cholangitis
94	Primary sclerosing cholangitis
96	Crohn disease
97	Ulcerative colitis
162	Pemphigoid
222	Primary nephrotic syndrome
229	Autoimmune pulmonary alveolar proteinosis
256	Muscle glycogenosis
271	Ankylosing spondylitis
274	Osteogenesis Imperfecta
283	Acquired pure red cell aplasia
284	Diamond-Blackfan anemia
285	Fanconi anemia
288	Autoimmune acquired coagulation factor deficiency
296	Biliary atresia
300	IgG4-related disease
331	Idiopathic multicentric castleman disease

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