Target Gene/Pathway Pathway / Gene

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KEGG GENES

KEGG PATHWAY

KEGG DRUG

DrugBank

Disease ID

1

[8] Fatty acid degradation, Fatty acid metabolism, PPAR signaling pathway, AMPK signaling pathway, T ...

Perhexiline 💬

[2] 58, 272 💬

2

[9] Fatty acid degradation, Fatty acid metabolism, PPAR signaling pathway, AMPK signaling pathway, T ...

Perhexiline 💬

[2] 58, 272 💬

3

[10] Fatty acid degradation, Fatty acid metabolism, PPAR signaling pathway, AMPK signaling pathway, ...

Perhexiline 💬

[2] 58, 272 💬

4

[5] Fatty acid degradation, Fatty acid metabolism, PPAR signaling pathway, Thermogenesis, Diabetic c ...

Perhexiline 💬

[2] 58, 272 💬

5

[2] PPAR signaling pathway, Cholesterol metabolism

Volanesorsen 💬

[1] 265 💬

6

[10] PPAR signaling pathway, cAMP signaling pathway, Adipocytokine signaling pathway, Glucagon signa ...

Fenofibrate 💬

[6] 8, 79, 93, 94, 97, 265 💬

7

[10] PPAR signaling pathway, cAMP signaling pathway, Adipocytokine signaling pathway, Glucagon signa ...

Bezafibrate 💬

[7] 20, 93, 94, 160, 296, 316, 324 💬

8

[10] PPAR signaling pathway, cAMP signaling pathway, Adipocytokine signaling pathway, Glucagon signa ...

Pemafibrate 💬

[1] 93 💬

9

[10] PPAR signaling pathway, cAMP signaling pathway, Adipocytokine signaling pathway, Glucagon signa ...

Elafibranor 💬

[2] 93, 94 💬

10

[11] PPAR signaling pathway, AMPK signaling pathway, Longevity regulating pathway, Osteoclast differ ...

Pioglitazone 💬

[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
6	Parkinson disease
13	Multiple sclerosis/Neuromyelitis optica
15	Inclusion body myositis
20	Adrenoleukodystrophy
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
65	Primary immunodeficiency
67	Polycystic kidney disease
78	Hypopituitarism
81	Congenital adrenal hyperplasia
86	Pulmonary arterial hypertension
96	Crohn disease
229	Autoimmune pulmonary alveolar proteinosis
265	Lipodystrophy
298	Hereditary pancreatitis
299	Cystic fibrosis

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