Target Gene/Pathway Pathway / Gene


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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 PDE10A 4件: Purine metabolism, Metabolic pathways, cAMP signaling pathway, Morphine addiction D07546 Bucladesine 1件: 246
2 CPS1 6件: Arginine biosynthesis, Alanine, aspartate and glutamate metabolism, Nitrogen metabolism, Metabolic pathways, Carbon metabolism, Biosynthesis of amino acids D07130 Carglumic acid 3件: 245, 246, 251
3 PDE7B 3件: Purine metabolism, Metabolic pathways, Morphine addiction D07546 Bucladesine 1件: 246
4 PDE11A 4件: Purine metabolism, Metabolic pathways, Cushing syndrome, Morphine addiction D07546 Bucladesine 1件: 246
5 PDE1A 7件: Purine metabolism, Metabolic pathways, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction D07546 Bucladesine 1件: 246
6 PDE1C 7件: Purine metabolism, Metabolic pathways, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction D07546 Bucladesine 1件: 246
7 PDE2A 6件: Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, Olfactory transduction, Aldosterone synthesis and secretion, Morphine addiction D07546 Bucladesine 1件: 246
8 PDE3A 6件: Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, cAMP signaling pathway, Renin secretion, Morphine addiction D07546 Bucladesine 1件: 246
9 PDE3B 11件: Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, cAMP signaling pathway, Apelin signaling pathway, Insulin signaling pathway, Progesterone-mediated oocyte maturation, Glucagon signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Morphine addiction D07546 Bucladesine 1件: 246
10 PDE4A 5件: Purine metabolism, Metabolic pathways, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction D07546 Bucladesine 1件: 246
11 PDE4B 5件: Purine metabolism, Metabolic pathways, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction D07546 Bucladesine 1件: 246
12 PDE4C 5件: Purine metabolism, Metabolic pathways, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction D07546 Bucladesine 1件: 246
13 PDE4D 5件: Purine metabolism, Metabolic pathways, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction D07546 Bucladesine 1件: 246
14 PDE7A 3件: Purine metabolism, Metabolic pathways, Morphine addiction D07546 Bucladesine 1件: 246
15 PDE8A 5件: Purine metabolism, Metabolic pathways, Cortisol synthesis and secretion, Cushing syndrome, Morphine addiction D07546 Bucladesine 1件: 246
16 PDE1B 7件: Purine metabolism, Metabolic pathways, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction D07546 Bucladesine 1件: 246
17 PDE8B 5件: Purine metabolism, Metabolic pathways, Cortisol synthesis and secretion, Cushing syndrome, Morphine addiction D07546 Bucladesine 1件: 246