Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 MASP2 3件: Complement and coagulation cascades, Staphylococcus aureus infection, Coronavirus disease - COVID-19 D11531 Narsoplimab 4件: 64, 66, 109, 222
2 CFD 3件: Complement and coagulation cascades, Staphylococcus aureus infection, Coronavirus disease - COVID-19 D11641 Danicopan 1件: 62
3 F2 8件: Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Platelet activation, Regulation of actin cytoskeleton, Pathogenic Escherichia coli infection, Coronavirus disease - COVID-19, Pathways in cancer D06410 Thrombomodulin Alfa 1件: 85
4 F2 8件: Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Platelet activation, Regulation of actin cytoskeleton, Pathogenic Escherichia coli infection, Coronavirus disease - COVID-19, Pathways in cancer D07144 Dabigatran etexilate 2件: 51, 75
5 F2 8件: Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Platelet activation, Regulation of actin cytoskeleton, Pathogenic Escherichia coli infection, Coronavirus disease - COVID-19, Pathways in cancer D09707 Dabigatran 5件: 51, 75, 85, 91, 124
6 F8 1件: Complement and coagulation cascades D00291 Desmopressin 6件: 6, 64, 72, 75, 225, 288
7 F9 1件: Complement and coagulation cascades D10821 Emicizumab 1件: 288
8 F10 1件: Complement and coagulation cascades D03213 Apixaban 1件: 222
9 F10 1件: Complement and coagulation cascades D07086 Rivaroxaban 4件: 46, 49, 91, 210
10 F10 1件: Complement and coagulation cascades D09710 Edoxaban 2件: 46, 88
11 F10 1件: Complement and coagulation cascades D10821 Emicizumab 1件: 288
12 SERPIND1 1件: Complement and coagulation cascades D08547 Sulodexide 2件: 51, 271
13 KLKB1 1件: Complement and coagulation cascades D10845 Conestat alfa 1件: 61
14 SERPINC1 1件: Complement and coagulation cascades D07510 Heparin 11件: 47, 60, 70, 84, 107, 224, 226, 280, 299, 316, 317
15 SERPINC1 1件: Complement and coagulation cascades D07510 Enoxaparin 1件: 46
16 SERPINC1 1件: Complement and coagulation cascades D07510 Parnaparin 1件: 97
17 SERPINC1 1件: Complement and coagulation cascades D08547 Sulodexide 2件: 51, 271
18 PLG 4件: Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Staphylococcus aureus infection, Influenza A D00160 Aminocaproic acid 1件: 70
19 PLG 4件: Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Staphylococcus aureus infection, Influenza A D01136 Tranexamic acid 7件: 46, 70, 215, 227, 274, 288, 299
20 CFB 3件: Complement and coagulation cascades, Staphylococcus aureus infection, Coronavirus disease - COVID-19 D12251 Iptacopan 5件: 61, 62, 66, 109, 222
21 C1R 6件: Phagosome, Complement and coagulation cascades, Pertussis, Staphylococcus aureus infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus D10845 Conestat alfa 1件: 61
22 C1S 5件: Complement and coagulation cascades, Pertussis, Staphylococcus aureus infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus D10845 Conestat alfa 1件: 61
23 C1S 5件: Complement and coagulation cascades, Pertussis, Staphylococcus aureus infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus D11530 Sutimlimab 1件: 61
24 C3 15件: Neuroactive ligand-receptor interaction, Phagosome, Complement and coagulation cascades, Neutrophil extracellular trap formation, Shigellosis, Pertussis, Legionellosis, Leishmaniasis, Staphylococcus aureus infection, Tuberculosis, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Coronavirus disease - COVID-19, Viral carcinogenesis, Systemic lupus erythematosus D11613 Pegcetacoplan 4件: 2, 61, 62, 222
25 C5 10件: Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Regulation of actin cytoskeleton, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus D03940 Eculizumab 7件: 11, 13, 14, 61, 62, 109, 222
26 C5 10件: Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Regulation of actin cytoskeleton, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus D11054 Ravulizumab 7件: 2, 11, 13, 50, 62, 66, 109
27 C5 10件: Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Regulation of actin cytoskeleton, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus D11473 Nomacopan 3件: 62, 109, 162
28 C5 10件: Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Regulation of actin cytoskeleton, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus D11477 Pozelimab 2件: 11, 62
29 C5 10件: Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Regulation of actin cytoskeleton, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus D11696 Crovalimab 2件: 62, 109
30 C5 10件: Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Regulation of actin cytoskeleton, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus D11838 Vilobelimab 3件: 43, 44, 269
31 C5 10件: Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Regulation of actin cytoskeleton, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus D12357 Zilucoplan 3件: 2, 11, 62
32 C5AR1 5件: Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Staphylococcus aureus infection, Coronavirus disease - COVID-19 D11093 Avacopan 3件: 43, 44, 222
33 VWF 8件: PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Complement and coagulation cascades, Platelet activation, Neutrophil extracellular trap formation, Human papillomavirus infection, Coronavirus disease - COVID-19 D11160 Caplacizumab 1件: 64