Target Gene/Pathway Pathway / Gene


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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 ACE 1件: Renin-angiotensin system D00251 Captopril 8件: 6, 17, 46, 86, 96, 97, 107, 271
2 ACE 1件: Renin-angiotensin system D00362 Lisinopril 7件: 19, 46, 49, 66, 67, 113, 222
3 ACE 1件: Renin-angiotensin system D00421 Ramipril 7件: 46, 49, 66, 67, 113, 218, 257
4 ACE 1件: Renin-angiotensin system D01069 Cilazapril 1件: 66
5 ACE 1件: Renin-angiotensin system D03752 Quinapril 1件: 19
6 ACE 1件: Renin-angiotensin system D03753 Perindopril 4件: 58, 113, 167, 222
7 ACE 1件: Renin-angiotensin system D07499 Benazepril 4件: 49, 57, 218, 224
8 ACE 1件: Renin-angiotensin system D07699 Cilazapril 1件: 66
9 ACE 1件: Renin-angiotensin system D07892 Enalapril 6件: 19, 46, 66, 113, 210, 222
10 ACE 1件: Renin-angiotensin system D08068 Imidapril 1件: 67
11 ACE 1件: Renin-angiotensin system D08131 Lisinopril 7件: 19, 46, 49, 66, 67, 113, 222
12 ACE 1件: Renin-angiotensin system D08225 Moexipril 1件: 93
13 AGTR1 2件: Vascular smooth muscle contraction, Renin-angiotensin system D00150 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224
14 AGTR1 2件: Vascular smooth muscle contraction, Renin-angiotensin system D00400 Valsartan 7件: 57, 58, 66, 75, 218, 222, 224
15 AGTR1 2件: Vascular smooth muscle contraction, Renin-angiotensin system D00522 Candesartan 2件: 58, 67
16 AGTR1 2件: Vascular smooth muscle contraction, Renin-angiotensin system D00523 Irbesartan 4件: 66, 167, 168, 222
17 AGTR1 2件: Vascular smooth muscle contraction, Renin-angiotensin system D00626 Candesartan cilexetil 1件: 67
18 AGTR1 2件: Vascular smooth muscle contraction, Renin-angiotensin system D00627 Telmisartan 2件: 66, 67
19 AGTR1 2件: Vascular smooth muscle contraction, Renin-angiotensin system D02014 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224
20 AGTR1 2件: Vascular smooth muscle contraction, Renin-angiotensin system D08146 Losartan 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
21 AGTR1 2件: Vascular smooth muscle contraction, Renin-angiotensin system D11776 Sparsentan 3件: 66, 218, 222
22 AGTR2 1件: Renin-angiotensin system D00150 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224
23 AGTR2 1件: Renin-angiotensin system D02014 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224
24 ANPEP 1件: Renin-angiotensin system D00087 Ubenimex 1件: 86
25 MME 1件: Renin-angiotensin system D10225 Sacubitril 2件: 58, 222
26 REN 1件: Renin-angiotensin system D03208 Aliskiren 3件: 66, 167, 222