Target Gene/Pathway Pathway / Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Acute myeloid leukemia 💬	[1] RELA 💬	D12181 💬	Edasalonexent	[1] 113 💬
2	Adipocytokine signaling pathway 💬	[2] PRKAA1, PRKAA2 💬	D04966 💬	Metformin	[25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 2 ...
3	Adipocytokine signaling pathway 💬	[1] RELA 💬	D12181 💬	Edasalonexent	[1] 113 💬
4	Adrenergic signaling in cardiomyocytes 💬	[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬	D00255 💬	Carvedilol	[4] 57, 86, 113, 210 💬
5	Adrenergic signaling in cardiomyocytes 💬	[1] ADRB1 💬	D02342 💬	Bisoprolol	[4] 58, 67, 86, 113 💬
6	Adrenergic signaling in cardiomyocytes 💬	[1] ADRB1 💬	D02358 💬	Metoprolol	[6] 17, 57, 58, 113, 193, 226 💬
7	Adrenergic signaling in cardiomyocytes 💬	[1] ADRB1 💬	D05127 💬	Nebivolol	[4] 17, 85, 113, 167 💬
8	Adrenergic signaling in cardiomyocytes 💬	[1] ADRB2 💬	D02147 💬	Salbutamol	[12] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
9	Adrenergic signaling in cardiomyocytes 💬	[1] AGTR1 💬	D08146 💬	Losartan	[17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
10	Adrenergic signaling in cardiomyocytes 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬

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