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KEGG GENES
KEGG PATHWAY
KEGG DRUG
DrugBank
指定難病告示番号
1
TNFSF13B
💬
1. TNFSF13B
×
Name
Full Name
TNFSF13B
TNF superfamily member 13b
4件:
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
NF-kappa B signaling pathway
,
Intestinal immune network for IgA production
,
Rheumatoid arthritis
4件:
Cytokine-cytokine receptor interaction
,
NF-kappa B signaling pathway
,
Intestinal immune network
...
Belimumab
Belimumab
💬
1. TNFSF13B
×
Name
Other Names
Belimumab
Belimumab (USAN)
Belimumab (genetical recombination) (JAN)
Benlysta (TN)
LymphoStat-B (TN)
ベリムマブ
ベンリスタ
Belimumab
13件:
11
11
,
13
,
43
,
44
,
46
,
49
,
51
,
53
,
63
,
66
,
222
,
296
,
300
💬
1. TNFSF13B
×
告示番号
日本語名
英語名
11
重症筋無力症
Myasthenia gravis
13
多発性硬化症／視神経脊髄炎
Multiple sclerosis/Neuromyelitis optica
43
顕微鏡的多発血管炎
Microscopic polyangiitis
44
多発血管炎性肉芽腫症;ウェゲナー肉芽腫症
Wegener granulomatosis
46
悪性関節リウマチ
Malignant rheumatoid arthritis
49
全身性エリテマトーデス
Systemic lupus erythematosus
51
全身性強皮症
Scleroderma
53
シェーグレン症候群
Sjogren syndrome
63
特発性血小板減少性紫斑病;一次性免疫性血小板減少症
Idiopathic thrombocytopenic purpura
66
IgA腎症
IgA nephropathy
222
一次性ネフローゼ症候群
Primary nephrotic syndrome
296
胆道閉鎖症
Biliary atresia
300
IgG4関連疾患
IgG4-related disease
2
MASP2
💬
2. MASP2
×
Name
Full Name
MASP2
mannan binding lectin serine peptidase 2
3件:
Complement and coagulation cascades
Complement and coagulation cascades
,
Staphylococcus aureus infection
,
Coronavirus disease - COVID-19
3件:
Complement and coagulation cascades
,
Staphylococcus aureus infection
,
Coronavirus disease - COVI
...
Narsoplimab
Narsoplimab
💬
2. MASP2
×
Name
Other Names
Narsoplimab
Narsoplimab (USAN)
ナルソプリマブ
Narsoplimab
4件:
64
64
,
66
,
109
,
222
💬
2. MASP2
×
告示番号
日本語名
英語名
64
血栓性血小板減少性紫斑病
Thrombotic thrombocytopenic purpura
66
IgA腎症
IgA nephropathy
109
非典型溶血性尿毒症症候群
Atypical hemolytic uremic syndrome
222
一次性ネフローゼ症候群
Primary nephrotic syndrome
3
MAPK14
💬
3. MAPK14
×
Name
Full Name
MAPK14
mitogen-activated protein kinase 14
62件:
Endocrine resistance
Endocrine resistance
,
MAPK signaling pathway
,
Rap1 signaling pathway
,
FoxO signaling pathway
,
Sphingolipid signaling pathway
,
Oocyte meiosis
,
Cellular senescence
,
Adrenergic signaling in cardiomyocytes
,
VEGF signaling pathway
,
Osteoclast differentiation
,
Signaling pathways regulating pluripotency of stem cells
,
Platelet activation
,
Neutrophil extracellular trap formation
,
Toll-like receptor signaling pathway
,
NOD-like receptor signaling pathway
,
RIG-I-like receptor signaling pathway
,
C-type lectin receptor signaling pathway
,
IL-17 signaling pathway
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
T cell receptor signaling pathway
,
Fc epsilon RI signaling pathway
,
TNF signaling pathway
,
Leukocyte transendothelial migration
,
Thermogenesis
,
Neurotrophin signaling pathway
,
Retrograde endocannabinoid signaling
,
Dopaminergic synapse
,
Inflammatory mediator regulation of TRP channels
,
GnRH signaling pathway
,
Progesterone-mediated oocyte maturation
,
Prolactin signaling pathway
,
Relaxin signaling pathway
,
Non-alcoholic fatty liver disease
,
AGE-RAGE signaling pathway in diabetic complications
,
Growth hormone synthesis, secretion and action
,
Alcoholic liver disease
,
Amyotrophic lateral sclerosis
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Epithelial cell signaling in Helicobacter pylori infection
,
Pathogenic Escherichia coli infection
,
Shigellosis
,
Salmonella infection
,
Pertussis
,
Yersinia infection
,
Leishmaniasis
,
Chagas disease
,
Toxoplasmosis
,
Tuberculosis
,
Hepatitis B
,
Human cytomegalovirus infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Epstein-Barr virus infection
,
Human immunodeficiency virus 1 infection
,
Coronavirus disease - COVID-19
,
Proteoglycans in cancer
,
Chemical carcinogenesis - reactive oxygen species
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
Diabetic cardiomyopathy
,
Lipid and atherosclerosis
,
Fluid shear stress and atherosclerosis
62件:
Endocrine resistance
,
MAPK signaling pathway
,
Rap1 signaling pathway
,
FoxO signaling pathway
,
S
...
Losmapimod
Losmapimod
💬
3. MAPK14
×
Name
Other Names
Losmapimod
Losmapimod (USAN/INN)
ロスマピモド
Losmapimod
2件:
113
113
,
222
💬
3. MAPK14
×
告示番号
日本語名
英語名
113
筋ジストロフィー
Muscular dystrophy
222
一次性ネフローゼ症候群
Primary nephrotic syndrome
4
ACE
💬
4. ACE
×
Name
Full Name
ACE
angiotensin I converting enzyme
6件:
Renin-angiotensin system
Renin-angiotensin system
,
Renin secretion
,
Chagas disease
,
Coronavirus disease - COVID-19
,
Hypertrophic cardiomyopathy
,
Diabetic cardiomyopathy
6件:
Renin-angiotensin system
,
Renin secretion
,
Chagas disease
,
Coronavirus disease - COVID-19
,
Hyper
...
Lisinopril
Lisinopril
💬
4. ACE
×
Name
Other Names
Lisinopril
Lisinopril (USP)
Lisinopril hydrate (JP18)
Lisinopril dihydrate
Prinivil (TN)
Zestril (TN)
QBRELIS
LISINORIL
リシノプリル水和物
ゼストリル
ロンゲス
リシノプリル
Lisinopril
7件:
19
19
,
46
,
49
,
66
,
67
,
113
,
222
💬
4. ACE
×
告示番号
日本語名
英語名
19
ライソゾーム病
Lysosomal storage disease
46
悪性関節リウマチ
Malignant rheumatoid arthritis
49
全身性エリテマトーデス
Systemic lupus erythematosus
66
IgA腎症
IgA nephropathy
67
多発性嚢胞腎
Polycystic kidney disease
113
筋ジストロフィー
Muscular dystrophy
222
一次性ネフローゼ症候群
Primary nephrotic syndrome
5
ACE
💬
5. ACE
×
Name
Full Name
ACE
angiotensin I converting enzyme
6件:
Renin-angiotensin system
Renin-angiotensin system
,
Renin secretion
,
Chagas disease
,
Coronavirus disease - COVID-19
,
Hypertrophic cardiomyopathy
,
Diabetic cardiomyopathy
6件:
Renin-angiotensin system
,
Renin secretion
,
Chagas disease
,
Coronavirus disease - COVID-19
,
Hyper
...
Perindopril
Perindopril
💬
5. ACE
×
Name
Other Names
Perindopril
Perindopril (USAN/INN)
ペリンドプリル
Perindopril
4件:
58
58
,
113
,
167
,
222
💬
5. ACE
×
告示番号
日本語名
英語名
58
肥大型心筋症
Hypertrophic cardiomyopathy
113
筋ジストロフィー
Muscular dystrophy
167
マルファン症候群
Marfan syndrome
222
一次性ネフローゼ症候群
Primary nephrotic syndrome
6
ACE
💬
6. ACE
×
Name
Full Name
ACE
angiotensin I converting enzyme
6件:
Renin-angiotensin system
Renin-angiotensin system
,
Renin secretion
,
Chagas disease
,
Coronavirus disease - COVID-19
,
Hypertrophic cardiomyopathy
,
Diabetic cardiomyopathy
6件:
Renin-angiotensin system
,
Renin secretion
,
Chagas disease
,
Coronavirus disease - COVID-19
,
Hyper
...
Enalapril
Enalapril
💬
6. ACE
×
Name
Other Names
Enalapril
Enalapril (INN)
Enalapril (TN)
エナラプリル
Enalapril
6件:
19
19
,
46
,
66
,
113
,
210
,
222
💬
6. ACE
×
告示番号
日本語名
英語名
19
ライソゾーム病
Lysosomal storage disease
46
悪性関節リウマチ
Malignant rheumatoid arthritis
66
IgA腎症
IgA nephropathy
113
筋ジストロフィー
Muscular dystrophy
210
単心室症
Single Ventricle
222
一次性ネフローゼ症候群
Primary nephrotic syndrome
7
ACE
💬
7. ACE
×
Name
Full Name
ACE
angiotensin I converting enzyme
6件:
Renin-angiotensin system
Renin-angiotensin system
,
Renin secretion
,
Chagas disease
,
Coronavirus disease - COVID-19
,
Hypertrophic cardiomyopathy
,
Diabetic cardiomyopathy
6件:
Renin-angiotensin system
,
Renin secretion
,
Chagas disease
,
Coronavirus disease - COVID-19
,
Hyper
...
Lisinopril
Lisinopril
💬
7. ACE
×
Name
Other Names
Lisinopril
Lisinopril (INN)
Zestril (TN)
リシノプリル
Lisinopril
7件:
19
19
,
46
,
49
,
66
,
67
,
113
,
222
💬
7. ACE
×
告示番号
日本語名
英語名
19
ライソゾーム病
Lysosomal storage disease
46
悪性関節リウマチ
Malignant rheumatoid arthritis
49
全身性エリテマトーデス
Systemic lupus erythematosus
66
IgA腎症
IgA nephropathy
67
多発性嚢胞腎
Polycystic kidney disease
113
筋ジストロフィー
Muscular dystrophy
222
一次性ネフローゼ症候群
Primary nephrotic syndrome
8
AGTR1
💬
8. AGTR1
×
Name
Full Name
AGTR1
angiotensin II receptor type 1
16件:
Calcium signaling pathway
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
Phospholipase D signaling pathway
,
Neuroactive ligand-receptor interaction
,
Adrenergic signaling in cardiomyocytes
,
Vascular smooth muscle contraction
,
Apelin signaling pathway
,
Renin-angiotensin system
,
Renin secretion
,
Aldosterone synthesis and secretion
,
Cortisol synthesis and secretion
,
AGE-RAGE signaling pathway in diabetic complications
,
Cushing syndrome
,
Coronavirus disease - COVID-19
,
Pathways in cancer
,
Diabetic cardiomyopathy
16件:
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
Phospholipase D signaling pathway
,
Neuro
...
Angiotensin II
Angiotensin II
💬
8. AGTR1
×
Name
Other Names
Angiotensin II
Angiotensin II (INN)
アンギオテンシンII
Angiotensin II
7件:
17
17
,
19
,
46
,
66
,
86
,
222
,
224
💬
8. AGTR1
×
告示番号
日本語名
英語名
17
多系統萎縮症
Multiple system atrophy
19
ライソゾーム病
Lysosomal storage disease
46
悪性関節リウマチ
Malignant rheumatoid arthritis
66
IgA腎症
IgA nephropathy
86
肺動脈性肺高血圧症
Pulmonary arterial hypertension
222
一次性ネフローゼ症候群
Primary nephrotic syndrome
224
紫斑病性腎炎
Purpura nephritis
9
AGTR1
💬
9. AGTR1
×
Name
Full Name
AGTR1
angiotensin II receptor type 1
16件:
Calcium signaling pathway
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
Phospholipase D signaling pathway
,
Neuroactive ligand-receptor interaction
,
Adrenergic signaling in cardiomyocytes
,
Vascular smooth muscle contraction
,
Apelin signaling pathway
,
Renin-angiotensin system
,
Renin secretion
,
Aldosterone synthesis and secretion
,
Cortisol synthesis and secretion
,
AGE-RAGE signaling pathway in diabetic complications
,
Cushing syndrome
,
Coronavirus disease - COVID-19
,
Pathways in cancer
,
Diabetic cardiomyopathy
16件:
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
Phospholipase D signaling pathway
,
Neuro
...
Valsartan
Valsartan
💬
9. AGTR1
×
Name
Other Names
Valsartan
Valsartan (JP18/USP/INN)
Diovan (TN)
バルサルタン
ディオバン
Valsartan
7件:
57
57
,
58
,
66
,
75
,
218
,
222
,
224
💬
9. AGTR1
×
告示番号
日本語名
英語名
57
特発性拡張型心筋症
Idiopathic dilated cardiomyopathy
58
肥大型心筋症
Hypertrophic cardiomyopathy
66
IgA腎症
IgA nephropathy
75
クッシング病
Cushing disease
218
アルポート症候群
Alport syndrome
222
一次性ネフローゼ症候群
Primary nephrotic syndrome
224
紫斑病性腎炎
Purpura nephritis
10
AGTR1
💬
10. AGTR1
×
Name
Full Name
AGTR1
angiotensin II receptor type 1
16件:
Calcium signaling pathway
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
Phospholipase D signaling pathway
,
Neuroactive ligand-receptor interaction
,
Adrenergic signaling in cardiomyocytes
,
Vascular smooth muscle contraction
,
Apelin signaling pathway
,
Renin-angiotensin system
,
Renin secretion
,
Aldosterone synthesis and secretion
,
Cortisol synthesis and secretion
,
AGE-RAGE signaling pathway in diabetic complications
,
Cushing syndrome
,
Coronavirus disease - COVID-19
,
Pathways in cancer
,
Diabetic cardiomyopathy
16件:
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
Phospholipase D signaling pathway
,
Neuro
...
Irbesartan
Irbesartan
💬
10. AGTR1
×
Name
Other Names
Irbesartan
Irbesartan (JP18/USP/INN)
Avapro (TN)
イルベサルタン
アバプロ
イルベタン
Irbesartan
4件:
66
66
,
167
,
168
,
222
💬
10. AGTR1
×
告示番号
日本語名
英語名
66
IgA腎症
IgA nephropathy
167
マルファン症候群
Marfan syndrome
168
エーラス・ダンロス症候群
Ehlers-Danlos syndrome
222
一次性ネフローゼ症候群
Primary nephrotic syndrome