Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Acetaminophen
(Synonym: Rx Act Nighttime Cold Flu Relief Multi Symptom)		[4] Acetaminophen; PARACETAMOL; Tylenol; Ultracet[1] D00217 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[15] 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337
2 Acetylsalicylic acid
(Synonym: Rx Act Aspirin)		[2] Acetylsalicylic acid; Aspirin[1] D00109 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251
3 Acteoside [1] Acteoside---[1] 66
4 Activated charcoal [1] Carbon---[6] 6, 85, 86, 96, 97, 158
5 Adenosine
(Synonym: ACTIBEAU Intensive Moisturizing Facial Mask)		[2] Adenosine; Ginseng[1] D00045 [4] ADORA1,
ADORA2A,
ADORA2B,
ADORA3 💬		[12] Alcoholism, Calcium signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 13, 58, 65
6 Alendronic acid
(Synonym: Act Alendronate)		[3] Alendronate; Alendronate sodium; ALENDRONIC ACID[1] D07119 [1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[7] 19, 41, 46, 50, 271, 274, 299
7 Alginic acid
(Synonym: Tums Dual Action)		[3] Algin; Alginate; Alginic acid[1] D02324 --[4] 51, 53, 97, 299
8 Allantoin
(Synonym: Correct Essential Activator)		[1] ALLANTOIN[1] D00121 --[1] 36
9 Aloe vera leaf
(Synonym: Re-action E)		[3] Aloe; Aloe vera; Aloe vera gel---[2] 97, 226
10 Aluminum hydroxide
(Synonym: Rx Act Antacid Extra Strength)		[2] Aluminium hydroxide; Aluminum hydroxide[1] D02416 --[2] 11, 46
11 Amlodipine
(Synonym: Act Amlodipine)		[1] Amlodipine[1] D07450 [4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 13, 51, 67, 298
12 Ammonium chloride
(Synonym: Ecopp Long Acting Antibacterial Disinfectant)		[1] Ammonium chloride[1] D01139 --[3] 96, 107, 251
13 Ascorbic acid
(Synonym: Acti-scorb 500 Caplet 500mg)		[4] Acidum ascorbicum; Ascorbic acid; Iron; Vitamin C[1] D00018 --[8] 10, 97, 192, 206, 210, 211, 212, 298
14 Atacicept
(Synonym: Human Transmembrane Activator and CAML Interactor)		[2] ATACICEPT; TACI-Fc5[1] D09704 [2] TNFSF13,
TNFSF13B 💬		[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[4] 13, 46, 49, 66
15 Atenolol
(Synonym: Act Atenolol)		[1] ATENOLOL[1] D00235 [1] ADRB1 💬[11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 167
16 Azithromycin
(Synonym: Act Azithromycin)		[5] Azithromycin; AZITHROMYCIN DIHYDRATE; Azithromycin monohydrate; AZITHROMYCINE; Zithromax[2] D06390 ,
D07486 		--[6] 13, 84, 85, 96, 228, 299
17 Beta carotene
(Synonym: Multi-actin)		[3] Beta carotene; Beta-Carotene; BETACAROTENE[1] D03101 --[2] 13, 96
18 Bezafibrate
(Synonym: Act-bezafibrate SR)		[1] Bezafibrate[1] D01366 [1] PPARA 💬[10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[7] 20, 93, 94, 160, 296, 316, 324
19 Biotin
(Synonym: Multi-actin)		[4] BIOTIN; Biotina; D-BIOTIN; Vitamin B7[1] D00029 --[5] 2, 8, 10, 13, 20
20 Bortezomib D-mannitol
(Synonym: Act Bortezomib)		[3] BORTEZOMIB; Bortezomib D-mannitol; Velcade---[3] 11, 28, 61
21 Bosentan
(Synonym: Act Bosentan)		[2] Bosentan; Tracleer[2] D01227 ,
D07538 		[2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212
22 Cabergoline
(Synonym: Act Cabergoline)		[3] CABERGOLINA; CABERGOLINE; DOSTINEX[1] D00987 [2] DRD2,
PRL 💬		[12] Alcoholism, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 6, 74, 75
23 Caffeine
(Synonym: Re-action E)		[1] Caffeine[2] D00528 ,
D01453 		[11] ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬		[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[8] 2, 6, 21, 46, 78, 96, 97, 265
24 Calcium
(Synonym: ENA Actimineral A)		[2] Calcio; Calcium---[27] 6, 13, 19, 46, 49, 51, 53, 56, 68, 75, 79, 84, 93, 94, 95, 96, 97, 156, 214, 215, 222, 224, 235, 265, 274, 298, 299
25 Calcium carbonate
(Synonym: Dual Action Complete)		[3] Calcio carbonato; Calcium; Calcium Carbonate[2] D00932 ,
D10802 		--[9] 13, 19, 46, 53, 75, 96, 235, 274, 299
26 Candesartan cilexetil
(Synonym: Act Candesartan/hct)		[1] CANDESARTAN[1] D00626 [1] AGTR1 💬[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 67
27 Capsaicin
(Synonym: Arthricare for Women Multi-action)		[2] Capsaicin; Qutenza[1] D00250 [1] TRPV1 💬[2] Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[3] 6, 86, 226
28 Celecoxib
(Synonym: Act Celecoxib)		[2] Celebrex; Celecoxib[1] D00567 [1] PTGS2 💬[22] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[10] 2, 3, 34, 46, 70, 89, 107, 161, 171, 271
29 Cetirizine
(Synonym: Rx Act all day allergy relief)		[3] Cetirizina; Cetirizine; CETIRIZINE HYDROCHLORIDE[1] D07662 [1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[4] 13, 28, 35, 300
30 Chlorpheniramine
(Synonym: Coricidin D Long Acting Tab)		[1] Clorfenamina[1] D07398 [1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[1] 14
31 Cholecalciferol
(Synonym: Active FE)		[5] Cholecalciferol; COLECALCIFEROL; Multivitamin; Vitamin D; Vitamin D3[1] D00188 [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[24] 6, 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299
32 Chromium
(Synonym: Multi-actin)		[1] Chromium---[1] 46
33 Ciprofloxacin
(Synonym: Act Ciprofloxacin)		[2] Ciprofloxacin; CIPROFLOXACIN HYDROCHLORIDE[1] D00186 --[5] 2, 60, 96, 97, 299
34 Citalopram
(Synonym: Act Citalopram)		[1] Citalopram[1] D07704 [1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[7] 6, 8, 13, 18, 46, 98, 127
35 Citric acid
(Synonym: bdr Re-action natural low base skin refiner exfoliation essence)		[1] Citric acid[1] D01222 --[2] 53, 291
36 Clarithromycin
(Synonym: Act Clarithromycin XL)		[1] Clarithromycin[1] D00276 --[8] 6, 63, 84, 96, 97, 222, 228, 299
37 Clopidogrel
(Synonym: Act Clopidogrel)		[1] Clopidogrel[3] D07729 ,
D10823 ,
D10824 		[1] P2RY12 💬[1] Platelet activation 💬[3] 49, 51, 86
38 Cobamamide
(Synonym: Acti-folic + Dibencozide Caplets)		[1] Cobamamide[1] D00042 --[1] 299
39 Copper
(Synonym: Actyform)		[2] Copper; Nicotinamide---[4] 2, 169, 170, 171
40 Corticorelin ovine triflutate
(Synonym: Acthrel)		[1] Acthrel[1] D03592 (Name: Acthrel (TN))[2] CRHR1,
CRHR2 💬		[4] Cushing syndrome, Long-term depression, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 75
41 Corticotropin
(Synonym: Acthar Powder Inj 40unit/vial)		[5] ACTH; ACTHAR; Adrenocorticotropic Hormone; Corticotrophin; Corticotropin[1] D00146 (Name: ACTH (TN))[1] MC2R 💬[5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[12] 2, 13, 14, 46, 49, 50, 66, 75, 81, 84, 145, 222
42 Cyanocobalamin
(Synonym: Active OB)		[2] Cianocobalamina; Vitamin B12[4] D00166 ,
D03615 ,
D03616 ,
D03617 		--[5] 6, 13, 201, 229, 299
43 Desloratadine
(Synonym: Aerius Dual Action 24 Hour)		[1] Desloratadine[1] D03693 [1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[1] 13
44 Dextran
(Synonym: Visine for Red Eye Triple Action)		[1] Dextran[1] D00060 --[4] 2, 62, 96, 97
45 Dextromethorphan
(Synonym: Activcin)		[4] Dextromethorphan; DEXTROMETHORPHAN HYDROBROMIDE; Dextrometorfano; Nuedexta[1] D03742 [6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
46 Diclofenac
(Synonym: Act Diclo-miso)		[3] Diclofenac; Diclofenac sodium; Diclofenac SR[1] D07816 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[5] 13, 34, 46, 78, 271
47 Diltiazem
(Synonym: Act Diltiazem T)		[2] Diltiazem; Diltiazem Hydrochloride[1] D07845 [4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 51, 58, 86
48 Diphenhydramine
(Synonym: Excedrin PM Triple Action Caplets)		[2] Diphenhydramine; Diphenhydramine hydrochloride[1] D00300 [1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[8] 11, 13, 49, 51, 70, 86, 222, 256
49 Doconexent
(Synonym: Active OB)		[2] Docosahexaenoic acid; Docosahexanoic Acid---[10] 6, 46, 48, 49, 90, 94, 113, 240, 299, 301
50 Donepezil
(Synonym: Act Donepezil ODT)		[3] Aricept; Donepezil; Donepezil hydrochloride[1] D07869 [1] ACHE 💬[2] Cholinergic synapse, Glycerophospholipid metabolism 💬[9] 5, 6, 13, 46, 78, 124, 127, 156, 206
51 Dorzolamide
(Synonym: Act Dorzotimolol)		[1] Dorzolamide[1] D07871 [13] CA1,
CA12,
CA13,
CA14,
CA2,
CA3,
CA4,
CA5A,
CA5B,
CA6,
CA7,
CA8,
CA9 💬		[7] Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬[1] 90
52 Doxycycline
(Synonym: Acticlate)		[4] Doxycyclin; Doxycycline; DOXYCYCLINE HYCLATE; Doxycycline Tablets[2] D00307 ,
D07876 		--[17] 13, 23, 28, 34, 46, 84, 85, 89, 96, 97, 158, 161, 162, 167, 227, 280, 299
53 Dutasteride
(Synonym: Act Dutasteride)		[2] Dutasterida; DUTASTERIDE[1] D03820 [2] SRD5A1,
SRD5A2 💬		[3] Metabolic pathways, Prostate cancer, Steroid hormone biosynthesis 💬[2] 1, 2
54 Enalapril
(Synonym: Act Enalapril)		[2] Enalapril; Enalapril Maleate[1] D07892 [1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[6] 19, 46, 66, 113, 210, 222
55 Ephedrine
(Synonym: Bronkaid Dual Action Formula)		[3] Efedrina; Ephedrine; EPHEDRINE HYDROCHLORIDE[1] D00124 [9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		[14] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 11
56 Ergocalciferol
(Synonym: Activated ergosterol)		[3] Ergocalciferol; Vitamin D; Vitamin D2[1] D00187 [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[6] 46, 49, 84, 96, 97, 299
57 Escitalopram
(Synonym: Act Escitalopram ODT)		[3] Citalopram; Escitalopram; Escitalopram oxalate[1] D07913 [1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[4] 2, 6, 13, 46
58 Estradiol
(Synonym: Activelle)		[1] Estradiol[1] D00105 [2] ESR1,
ESR2 💬		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[7] 13, 46, 49, 65, 76, 226, 299
59 Ethanol
(Synonym: Non-Negotiables Fast-Acting Sanitizing)		[3] Alcohol; Ethanol; PREDNISONE[1] D06542 --[5] 58, 97, 279, 280, 298
60 Etidronic acid
(Synonym: Act Etidrocal)		[1] Etidronate[1] D02373 --[1] 27
61 Ezetimibe
(Synonym: Act Ezetimibe)		[2] Ezetimibe; Ezetrol[1] D01966 [1] NPC1L1 💬[1] Fat digestion and absorption 💬[4] 49, 79, 93, 260
62 Famciclovir
(Synonym: Act Famciclovir)		[1] Famciclovir[1] D00317 --[2] 11, 13
63 Famotidine
(Synonym: Up and Up Acid Controller Complete Dual Action)		[2] FAMOTIDINA; Famotidine[1] D00318 [1] HRH2 💬[3] Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬[6] 6, 46, 61, 86, 98, 107
64 Fentanyl
(Synonym: Actiq)		[1] Fentanyl[1] D00320 [1] OPRM1 💬[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[3] 46, 70, 215
65 Finasteride
(Synonym: Act Finasteride)		[1] Finasteride[1] D00321 [1] SRD5A2 💬[3] Metabolic pathways, Prostate cancer, Steroid hormone biosynthesis 💬[1] 6
66 Fluconazole
(Synonym: Act Fluconazole)		[2] Diflucan; FLUCONAZOLE[1] D00322 --[2] 96, 225
67 Fluoxetine
(Synonym: Act Fluoxetine)		[5] Fluoxetin; FLUOXETINE; FLUOXETINE HYDROCHLORIDE; Fluoxétine; PROZAC[1] D00326 [1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[6] 13, 17, 78, 86, 179, 206
68 Fluticasone propionate
(Synonym: Flovent Inhalers-aem Inh-orl250mcg/actuation)		[3] Flovent; Fluticasone; Fluticasone propionate[1] D01708 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[2] 98, 228
69 Folic acid
(Synonym: Active OB)		[5] Acide folique; Folate; Folic Acid; Multivitamin; Nicotinamide[1] D00070 --[6] 6, 41, 46, 49, 84, 296
70 Fulvestrant
(Synonym: Act Fulvestrant)		[2] Faslodex; Fulvestrant[1] D01161 [2] ESR1,
ESR2 💬		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[2] 49, 86
71 Furosemide
(Synonym: Active-Medicated specimen collection kit)		[2] Furosemide; Furosemide Injection[1] D00331 [1] SLC12A2 💬[3] Pancreatic secretion, Salivary secretion, Vibrio cholerae infection 💬[2] 6, 86
72 Gabapentin
(Synonym: ACTIVE-PAC with Gabapentin)		[4] GABAPENTIN; GABAPENTINA; Gabapentine; NEURONTIN[1] D00332 [5] CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4,
SLC6A1 💬		[9] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway, Synaptic vesicle cycle 💬[5] 6, 13, 19, 70, 298
73 Glycerin
(Synonym: TONYMOLY Bio EX Active-Cell Eye-Face Cream)		[2] Bee venom; Glycerol[1] D00028 --[5] 6, 13, 79, 316, 317
74 Glycolic acid
(Synonym: bdr Re-action deep low base skin refiner exfoliation essence)		[1] Glycolic acid---[1] 65
75 Haemophilus influenzae type B strain 1482 capsular polysaccharide tetanus toxoid conjugate antigen
(Synonym: ActHIB)		[2] ACT-HIB; ActHIB---[5] 14, 61, 62, 66, 222
76 Haloperidol
(Synonym: Haloperidol Long Acting)		[1] Haloperidol[1] D00136 [1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 8
77 Hyaluronic acid
(Synonym: ACTS38 BoswelliaGel)		[2] Hyaluronate; Hyaluronic acid[1] D08043 --[6] 46, 53, 70, 97, 226, 231
78 Hydrochlorothiazide
(Synonym: Act Candesartan/hct)		[2] Esidrix; Hydrochlorothiazide[1] D00340 [1] SLC12A3 💬-[4] 13, 67, 225, 235
79 Hydrocortisone [6] Cortef; Cortisol; Cortisone; Hydrocortisone; Hydrocortisone cream; Hydrocortisonum[1] D00088 (Name: Acticort (TN))[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[10] 6, 41, 46, 53, 75, 78, 81, 83, 97, 299
80 Hydrocortisone acetate
(Synonym: Actinac Pwr)		[2] Hydrocortisone; HYDROCORTISONE ACETATE[1] D00165 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 97
81 Ibuprofen
(Synonym: Rx Act Ibuprofen)		[2] Ibuprofen; IBUPROFEN 200MG[1] D00126 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[7] 13, 46, 65, 107, 113, 271, 299
82 Imatinib
(Synonym: Imatinib Actavis)		[4] Gleevec; GLIVEC; Imatinib; Imatinib Mesylate[1] D08066 [3] ABL1,
KIT,
PDGFRA 💬		[32] Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Choline metabolism in cancer, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis 💬[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
83 Indian frankincense
(Synonym: ACTS38 BoswelliaGel)		[2] Boswellia Serrata; Boswellia Serrata Extract---[1] 13
84 Insulin human
(Synonym: Actraphane 30 Flexpen)		[1] Human insulin[1] D03230 [1] INSR 💬[22] AMPK signaling pathway, Adherens junction, Aldosterone-regulated sodium reabsorption, Alzheimer disease, Diabetic cardiomyopathy, FoxO signaling pathway, HIF-1 signaling pathway, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Non-alcoholic fatty liver disease, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway, Regulation of lipolysis in adipocytes, Type II diabetes mellitus, cGMP-PKG signaling pathway, mTOR signaling pathway 💬[2] 96, 156
85 Insulin-like growth factor II
(Synonym: Multiplication-stimulating activity III-2)		[0] ---[1] 19
86 Interferon gamma-1b
(Synonym: Actimmune)		[2] ACTIMMUNE; INTERFERON GAMMA-1B[1] D00747 (Name: Actimmune (TN))[2] IFNGR1,
IFNGR2 💬		[18] Chagas disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis 💬[7] 18, 65, 85, 228, 299, 301, 326
87 Iodine
(Synonym: Multi-actin)		[2] Iodine; Iodo[1] D00108 --[2] 28, 46
88 Irbesartan
(Synonym: Act Irbesartan)		[2] Aprovel; IRBESARTAN[1] D00523 [1] AGTR1 💬[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[4] 66, 167, 168, 222
89 Iron
(Synonym: Active FE)		[1] Iron---[6] 18, 96, 97, 238, 254, 284
90 Levetiracetam
(Synonym: Levetiracetam Actavis Group)		[2] KEPPRA; Levetiracetam[1] D00709 [1] SV2A 💬[1] ECM-receptor interaction 💬[5] 2, 4, 6, 13, 307
91 Levofloxacin
(Synonym: Act Levofloxacin)		[2] Levaquin; Levofloxacin[2] D00588 ,
D08120 		--[5] 46, 53, 84, 85, 299
92 Levonorgestrel
(Synonym: Take Action)		[1] LEVONORGESTREL[1] D00950 [1] PGR 💬[5] Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬[1] 13
93 Lidocaine
(Synonym: biochemistry PAIN RELIEF FOOT ACTIVE)		[4] Aloe; Lidocaine; Lignocaine; Xylocaine[2] D00358 ,
D08127 		[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256
94 Lisinopril
(Synonym: Act Lisinopril)		[2] Lisinopril; Zestril[2] D00362 ,
D08131 		[1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[7] 19, 46, 49, 66, 67, 113, 222
95 Loperamide
(Synonym: Rx Act Anti Diarrheal)		[2] LOPERAMIDE; Loperamide hydrochloride[1] D08144 [3] OPRD1,
OPRK1,
OPRM1 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[2] 13, 97
96 Losartan
(Synonym: Act Losartan)		[3] Cozaar; Losartan; LOSARTAN POTASSIUM[1] D08146 [1] AGTR1 💬[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
97 Lovastatin
(Synonym: Act Lovastatin)		[1] Lovastatin[1] D00359 [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[11] 6, 34, 46, 79, 156, 160, 195, 206, 263, 280, 310
98 Magnesium
(Synonym: Usana Optimizer Actical Plus Calcium-magnesium-vitamin D3-silicon Tablets)		[1] Magnesium---[19] 6, 11, 13, 46, 51, 63, 64, 70, 93, 97, 111, 166, 225, 235, 284, 291, 296, 297, 298
99 Magnesium hydroxide
(Synonym: Smart Sense Dual Action Complete)		[1] Magnesium hydroxide[1] D00731 --[1] 284
100 Magnesium oxide
(Synonym: Active FE)		[1] Magnesium oxide[1] D01167 --[3] 6, 166, 291
101 Maltodextrin
(Synonym: Re-action E)		[1] Maltodextrin[1] D02329 --[4] 6, 13, 96, 97
102 Meloxicam
(Synonym: Act Meloxicam)		[1] Meloxicam[1] D00969 [1] PTGS2 💬[22] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[4] 46, 49, 271, 296
103 Memantine
(Synonym: Act Memantine)		[3] EBIXA; Memantine; Memantine hydrochloride[1] D08174 [5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[8] 2, 6, 8, 13, 49, 127, 205, 206
104 Metformin
(Synonym: Actoplus Met)		[5] Metformin; Metformin HCl; Metformin hydrochloride; METFORMINA; Metformine[1] D04966 [2] PRKAA1,
PRKAA2 💬		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[25] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301
105 Methylphenidate
(Synonym: Act Methylphenidate ER)		[3] Methylphenidate; METHYLPHENIDATE HYDROCHLORIDE; Ritalin[1] D04999 [2] SLC6A2,
SLC6A3 💬		[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[7] 6, 13, 34, 84, 113, 179, 206
106 Mineral oil
(Synonym: Phillips Dual Action)		[1] Paraffin Oil[1] D05042 --[1] 291
107 Misoprostol
(Synonym: Act Diclo-miso)		[1] Misoprostol[1] D00419 [3] PTGER2,
PTGER3,
PTGER4 💬		[9] Calcium signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Pathways in cancer, Regulation of lipolysis in adipocytes, Renin secretion, cAMP signaling pathway 💬[3] 46, 70, 271
108 Moxifloxacin
(Synonym: Act Moxifloxacin)		[2] Moxifloxacin; Moxifloxacin Hydrochloride[1] D08237 --[9] 2, 6, 46, 49, 85, 86, 113, 240, 299
109 Nabilone
(Synonym: Act Nabilone)		[1] NABILONE[1] D05099 [2] CNR1,
CNR2 💬		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[3] 6, 13, 127
110 Naproxen
(Synonym: Rx Act Naproxen Sodium)		[5] Naprosyn; Naproxen; Naproxen oral suspension; NAPROXEN SODIUM; Propanoic acid[1] D00118 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[4] 13, 46, 107, 271
111 Neomycin
(Synonym: Multi Action)		[1] Neomycin[1] D08260 --[3] 96, 97, 296
112 Niacin
(Synonym: Multi-actin)		[2] Niacin; Nicotinic acid[1] D00049 --[3] 6, 78, 79
113 Nicotinamide
(Synonym: Incellderm Active)		[3] Multivitamin; Niacinamide; Nicotinamide[1] D00036 --[10] 2, 5, 6, 18, 49, 67, 97, 107, 162, 191
114 Nifedipine
(Synonym: Nu-nifedipine-PA - Prolonged Action Tab)		[1] Nifedipine[1] D00437 [4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 50, 81
115 Norethisterone
(Synonym: Activelle Ld)		[3] Norethindrone; Ortho-novum; Ortho-Novum 777[1] D00182 [1] PGR 💬[5] Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬[4] 13, 46, 49, 299
116 Olanzapine
(Synonym: Act Olanzapine ODT)		[2] Olanzapine; Zyprexa[1] D00454 [11] ADRA1A,
ADRA1B,
ADRA1D,
DRD2,
DRD3,
DRD4,
HRH1,
HTR2A,
HTR2B,
HTR2C,
HTR6 💬		[16] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Salivary secretion, Serotonergic synapse, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 2, 8
117 Oxycodone
(Synonym: Act Oxycodone CR)		[2] OXYCODONE; OXYCODONE HYDROCHLORIDE[1] D05312 [3] OPRD1,
OPRK1,
OPRM1 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[5] 6, 13, 70, 226, 298
118 Pantoprazole
(Synonym: Act Pantoprazole)		[1] PANTOPRAZOLE[1] D05353 [2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[2] 13, 65
119 Paroxetine
(Synonym: Act Paroxetine)		[1] Paroxetine[1] D02362 [1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[4] 6, 13, 46, 85
120 Petrolatum
(Synonym: Rx Act Hemorrhoidal)		[1] Petrolatum[1] D05331 --[1] 158
121 Phenylephrine
(Synonym: Equaline Fast Acting)		[1] Phenylephrine[1] D08365 [3] ADRA1A,
ADRA1B,
ADRA1D 💬		[7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 22
122 Pioglitazone
(Synonym: Actoplus Met)		[1] Pioglitazone[1] D08378 (Name: Actos (TN))[1] PPARG 💬[11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299
123 Potassium
(Synonym: Multi-actin)		[1] Potassium[1] D08403 --[13] 36, 46, 66, 67, 88, 93, 94, 98, 115, 167, 179, 215, 235
124 Pramipexole
(Synonym: Act Pramipexole)		[7] Mirapex; Mirapex ER; Mirapexin; Pramipexol; PRAMIPEXOLE; PRAMIPEXOLE DIHYDROCHLORIDE; SIFROL[1] D05575 [3] DRD2,
DRD3,
DRD4 💬		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 2, 6, 20
125 Pravastatin
(Synonym: Act Pravastatin)		[2] Pravastatin; Pravastatin sodium[1] D08410 [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[9] 13, 46, 49, 67, 79, 96, 164, 265, 333
126 Pregabalin
(Synonym: Act Pregabalin)		[2] Lyrica; Pregabalin[1] D02716 [4] CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4 💬		[7] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway 💬[5] 13, 36, 46, 70, 298
127 Progesterone
(Synonym: Act Progesterone Injection)		[1] Progesterone[1] D00066 [1] PGR 💬[5] Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬[2] 76, 299
128 Pseudoephedrine
(Synonym: Aerius Dual Action 24 Hour)		[1] Pseudoephedrine[1] D08449 [9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		[14] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 17
129 Pyridoxine
(Synonym: Active FE)		[2] Pyridoxine; Vitamin B6[1] D08454 --[5] 6, 93, 145, 206, 320
130 Quetiapine
(Synonym: Act Quetiapine)		[2] Quetiapine; Seroquel[1] D08456 [2] DRD2,
HTR2A 💬		[11] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬[2] 6, 13
131 Raloxifene
(Synonym: Act Raloxifene)		[2] Raloxifene; Raloxifene hydrochloride[1] D08465 [2] ESR1,
ESR2 💬		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[1] 46
132 Ramipril
(Synonym: Act Ramipril)		[1] Ramipril[1] D00421 [1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[7] 46, 49, 66, 67, 113, 218, 257
133 Ranitidine
(Synonym: Act Ranitidine)		[1] Ranitidine[1] D00422 [1] HRH2 💬[3] Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬[2] 13, 65
134 Repaglinide
(Synonym: Act Repaglinide)		[1] Repaglinide[1] D00594 [2] ABCC8,
KCNJ11 💬		[4] ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬[4] 6, 21, 46, 299
135 Riboflavin
(Synonym: Active FE)		[2] Riboflavin; Vitamin B2[1] D00050 --[7] 38, 46, 96, 97, 162, 168, 265
136 Risedronic acid
(Synonym: Actonel with Calcium)		[3] Risedronate; Risedronate Sodium; Risedronic acid[1] D08484 [1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[9] 46, 50, 66, 93, 95, 96, 107, 113, 274
137 Risperidone
(Synonym: Act Risperidone)		[1] Risperidone[1] D00426 [2] DRD2,
HTR2A 💬		[11] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬[5] 8, 156, 179, 187, 206
138 Rivastigmine
(Synonym: Rivastigmine Actavis)		[3] EXELON; Rivastigmine; Rivastigmine Transdermal System[1] D03822 [1] ACHE 💬[2] Cholinergic synapse, Glycerophospholipid metabolism 💬[3] 5, 6, 13
139 Rosuvastatin
(Synonym: Act Rosuvastatin)		[3] Crestor; Rosuvastatin; ROSUVASTATIN CALCIUM[1] D08492 [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[11] 6, 18, 46, 49, 51, 56, 79, 96, 97, 271, 299
140 Salicylic acid
(Synonym: Aveeno Active naturals Clear Complexion Cleanser)		[2] 2-Hydroxybenzoic acid; Salicylic acid[1] D00097 --[1] 97
141 Selenium
(Synonym: Multi-actin)		[1] Selenium---[4] 13, 96, 278, 298
142 Sertraline
(Synonym: Act Sertraline)		[1] Sertraline[1] D02360 [1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[2] 6, 206
143 Sildenafil
(Synonym: Act Sildenafil)		[6] Mysildecard; Revatio; Sildenafil; SILDENAFIL CITRATE; SILDENAFILO; VIAGRA[1] D08514 [1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[17] 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301
144 Simvastatin
(Synonym: Act Simvastatin)		[3] Simvastatin; Simvastatina; Simvastatine[1] D00434 [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[21] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310
145 Sodium fluoride
(Synonym: ACT Anticavity Fluoride Iced Sweet Mint)		[1] Sodium fluoride[1] D00943 --[1] 51
146 Solifenacin
(Synonym: Act Solifenacin)		[2] Solifenacin; Solifenacin Succinate[1] D08522 [1] CHRM3 💬[11] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬[3] 6, 13, 53
147 Spectinomycin
(Synonym: Actinospectacina)		[0] [1] D08526 --[1] 13
148 Tadalafil
(Synonym: Act Tadalafil)		[4] Adcirca; Cialis; Tadalafil; TADALAFILO[1] D02008 [1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[7] 6, 51, 75, 84, 86, 113, 210
149 Telmisartan
(Synonym: Telmisartan Actavis)		[1] Telmisartan[1] D00627 [1] AGTR1 💬[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[2] 66, 67
150 Temozolomide
(Synonym: Act Temozolomide)		[1] Temozolomide[1] D06067 --[1] 34
151 Terbinafine
(Synonym: Act Terbinafine)		[1] Terbinafine[1] D02375 --[3] 96, 97, 271
152 Tetracycline
(Synonym: Actisite)		[2] Tetracyclin; Tetracycline[1] D00201 --[5] 13, 36, 46, 53, 97
153 Thiamine
(Synonym: Active FE)		[2] THIAMINE; Vitamin B1[1] D08580 --[4] 8, 93, 145, 265
154 Timolol
(Synonym: Act Latanoprost/timolol)		[2] Timolol; TIMOLOL MALEATE[2] D00378 ,
D08600 		[2] ADRB1,
ADRB2 💬		[11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 157, 227
155 Tocilizumab
(Synonym: Actemra)		[3] Actemra; RoActemra; TOCILIZUMAB[1] D02596 (Name: Actemra (TN))[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[21] 2, 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331
156 Topotecan
(Synonym: Topotecan Actavis)		[1] Topotecan[1] D08618 [1] TOP1 💬-[1] 25
157 Tramadol
(Synonym: Act Tramadol/acet)		[2] Tramadol; Ultracet[1] D08623 [1] OPRM1 💬[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[5] 46, 70, 78, 226, 271
158 Tremelimumab [1] Ticilimumab[1] D06657 (Name: Tremelimumab-actl)[1] CTLA4 💬[4] Autoimmune thyroid disease, Cell adhesion molecules, Rheumatoid arthritis, T cell receptor signaling pathway 💬[1] 96
159 Ubidecarenone
(Synonym: Acti-ubiquinone 50 Cap 50mg)		[3] Coenzyme Q-10; Coenzyme Q10; CoQ10[1] D01065 --[12] 2, 5, 6, 8, 10, 18, 46, 57, 86, 113, 214, 215
160 Ursodeoxycholic acid
(Synonym: Actigall)		[4] UDCA; URSODEOXYCHOLIC ACID; Ursodiol; UrsoFalk[1] D00734 (Name: Actigall (TN))[1] NR1H4 💬[1] Bile secretion 💬[14] 6, 8, 20, 46, 67, 84, 93, 94, 95, 96, 97, 234, 296, 299
161 Valsartan
(Synonym: Act Valsartan)		[3] Diovan; Entresto; Valsartan[1] D00400 [1] AGTR1 💬[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[7] 57, 58, 66, 75, 218, 222, 224
162 Venlafaxine
(Synonym: Act Venlafaxine XR)		[2] Venlafaxine; VENLAFAXINE HYDROCHLORIDE[1] D08670 [2] SLC6A2,
SLC6A4 💬		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[3] 6, 13, 46
163 Vitamin A
(Synonym: Multi-actin)		[1] Vitamin A[1] D06543 [2] RARA,
RARB 💬		[8] Acute myeloid leukemia, Estrogen signaling pathway, Gastric cancer, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer 💬[3] 13, 53, 90
164 Vitamin E
(Synonym: Acti-D Alphacopherol Cap 400unit)		[2] Alpha-tocopherol; Vitamin E[1] D02331 --[12] 2, 6, 13, 20, 46, 49, 90, 96, 97, 206, 299, 317
165 Water
(Synonym: Activase RT-PA)		[8] AVONEX; ENBREL; Hiberix; Indocyanine green; OMNITROPE; Sterile Water for Injection; Water; WATER FOR INJECTION[1] D00001 --[21] 2, 5, 6, 13, 17, 22, 35, 46, 53, 57, 63, 65, 67, 78, 84, 96, 97, 206, 226, 278, 299
166 Zinc
(Synonym: Acti-cal/mag 2)		[3] Nicotinamide; Wilzin; Zinc---[4] 2, 113, 171, 299
167 Zinc acetate
(Synonym: Action Cream)		[2] Wilzin; Zinc acetate[1] D06408 --[2] 171, 299
168 Zinc oxide
(Synonym: SPF 50 plus Sunscreen All Mineral Active Ingredients)		[1] Zinc oxide[1] D01170 --[1] 156
169 Zoledronic acid
(Synonym: Act Zoledronic Acid Concentrate)		[4] ACLASTA; Zoledronate; Zoledronic acid; Zometa[2] D01968 ,
D08689 		[1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[13] 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333
170 Zopiclone
(Synonym: Act Zopiclone)		[1] Zopiclone[1] D01372 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[1] 6