Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	Disease ID
1	CDK4	[2] Tight junction, Viral carcinogenesis	D10688	Abemaciclib	[1] 34
2	CFTR	[2] Tight junction, Vibrio cholerae infection	D09916	Ivacaftor	[1] 299
3	CFTR	[2] Tight junction, Vibrio cholerae infection	D10134	Lumacaftor	[1] 299
4	CFTR	[2] Tight junction, Vibrio cholerae infection	D11041	Tezacaftor	[1] 299
5	CFTR	[2] Tight junction, Vibrio cholerae infection	D11423	Deutivacaftor	[1] 299
6	CFTR	[2] Tight junction, Vibrio cholerae infection	D11507	Elexacaftor	[1] 299
7	CFTR	[2] Tight junction, Vibrio cholerae infection	D11724	Galicaftor	[1] 299
8	ERBB2	[1] Tight junction	D08108	Lapatinib	[3] 34, 74, 75
9	ERBB2	[1] Tight junction	D08950	Neratinib	[1] 34
10	ERBB2	[1] Tight junction	D11772	Tesevatinib	[1] 67

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