Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 ERBB2 [4] Platinum drug resistance, Tight junction, Proteoglycans in cancer, Prostate cancer D08108 Lapatinib [3] 34, 74, 75
2 ERBB2 [4] Platinum drug resistance, Tight junction, Proteoglycans in cancer, Prostate cancer D08950 Neratinib [1] 34
3 ERBB2 [4] Platinum drug resistance, Tight junction, Proteoglycans in cancer, Prostate cancer D11772 Tesevatinib [1] 67
4 MAP3K5 [7] Platinum drug resistance, Sphingolipid signaling pathway, Protein processing in endoplasmic reticulum, Tight junction, TNF signaling pathway, Thermogenesis, Spinocerebellar ataxia D10988 Selonsertib [1] 86
5 PIK3CA [26] Platinum drug resistance, Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Prion disease, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Small cell lung cancer D11011 Alpelisib [1] 138
6 PIK3CA [26] Platinum drug resistance, Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Prion disease, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Small cell lung cancer D11158 Leniolisib [2] 53, 65
7 PIK3CB [26] Platinum drug resistance, Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Prion disease, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Small cell lung cancer D11158 Leniolisib [2] 53, 65
8 PIK3CD [26] Platinum drug resistance, Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Prion disease, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Small cell lung cancer D11158 Leniolisib [2] 53, 65
9 PIK3CD [26] Platinum drug resistance, Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Prion disease, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Small cell lung cancer D11437 Parsaclisib [3] 35, 53, 61
10 BCL2 [9] Platinum drug resistance, Sphingolipid signaling pathway, Protein processing in endoplasmic reticulum, Shigellosis, Salmonella infection, Toxoplasmosis, Tuberculosis, Prostate cancer, Small cell lung cancer D10679 Venetoclax [1] 28
11 TOP2A [1] Platinum drug resistance D00125 Etoposide [11] 11, 13, 14, 26, 28, 34, 60, 65, 85, 164, 331
12 TOP2A [1] Platinum drug resistance D03730 Dexrazoxane [1] 13
13 TOP2A [1] Platinum drug resistance D03899 Doxorubicin [5] 26, 28, 34, 65, 331
14 TOP2A [1] Platinum drug resistance D05522 Pixantrone [2] 11, 13
15 TOP2A [1] Platinum drug resistance D07776 Daunorubicin [1] 65
16 TOP2A [1] Platinum drug resistance D08224 Mitoxantrone [1] 13
17 TOP2B [1] Platinum drug resistance D00125 Etoposide [11] 11, 13, 14, 26, 28, 34, 60, 65, 85, 164, 331
18 TOP2B [1] Platinum drug resistance D03730 Dexrazoxane [1] 13
19 TOP2B [1] Platinum drug resistance D03899 Doxorubicin [5] 26, 28, 34, 65, 331
20 TOP2B [1] Platinum drug resistance D05522 Pixantrone [2] 11, 13
21 TOP2B [1] Platinum drug resistance D07776 Daunorubicin [1] 65
22 TOP2B [1] Platinum drug resistance D08224 Mitoxantrone [1] 13
23 CASP9 [9] Platinum drug resistance, VEGF signaling pathway, Thyroid hormone signaling pathway, Prion disease, Toxoplasmosis, Tuberculosis, Prostate cancer, Small cell lung cancer, Viral myocarditis D11195 Rimiducid [6] 19, 60, 65, 284, 285, 326