Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	Disease ID
1	MAPK14	[17] Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripote ...	D09639	Losmapimod	[2] 113, 222
2	MAPK14	[17] Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripote ...	D10959	Neflamapimod	[1] 8
3	EDNRB	[1] Relaxin signaling pathway	D01227	Bosentan	[10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212
4	EDNRB	[1] Relaxin signaling pathway	D07538	Bosentan	[10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212
5	EDNRB	[1] Relaxin signaling pathway	D10135	Macitentan	[5] 51, 85, 86, 88, 210
6	EGFR	[2] Relaxin signaling pathway, Shigellosis	D01977	Gefitinib	[1] 75
7	EGFR	[2] Relaxin signaling pathway, Shigellosis	D03455	Cetuximab	[2] 51, 86
8	EGFR	[2] Relaxin signaling pathway, Shigellosis	D07907	Erlotinib	[1] 94
9	EGFR	[2] Relaxin signaling pathway, Shigellosis	D08108	Lapatinib	[3] 34, 74, 75
10	EGFR	[2] Relaxin signaling pathway, Shigellosis	D08950	Neratinib	[1] 34

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