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KEGG GENES
KEGG PATHWAY
KEGG DRUG
DrugBank
Disease ID
1
JAK1
💬
1. JAK1
×
Name
Full Name
JAK1
Janus kinase 1
[27]
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
PI3K-Akt signaling pathway
,
Necroptosis
,
Osteoclast differentiation
,
Signaling pathways regulating pluripotency of stem cells
,
NOD-like receptor signaling pathway
,
JAK-STAT signaling pathway
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
Leishmaniasis
,
Toxoplasmosis
,
Tuberculosis
,
Hepatitis C
,
Hepatitis B
,
Measles
,
Human cytomegalovirus infection
,
Influenza A
,
Human papillomavirus infection
,
Human T-cell leukemia virus 1 infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Herpes simplex virus 1 infection
,
Epstein-Barr virus infection
,
Coronavirus disease - COVID-19
,
Pathways in cancer
,
Viral carcinogenesis
,
Pancreatic cancer
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
[27]
EGFR tyrosine kinase inhibitor resistance
,
PI3K-Akt signaling pathway
,
Necroptosis
,
Osteoclast
...
Baricitinib
Baricitinib
💬
1. JAK1
×
Name
Other Names
Baricitinib
Baricitinib (JAN/USAN/INN)
Olumiant (TN)
OTHER BARICITINIB
Baricitinib
[13]
2
2
,
41
,
46
,
49
,
50
,
51
,
53
,
93
,
107
,
162
,
265
,
269
,
325
💬
1. JAK1
×
Disease ID
Name
2
Amyotrophic lateral sclerosis
41
Giant cell arteritis
46
Malignant rheumatoid arthritis
49
Systemic lupus erythematosus
50
Dermatomyositis
51
Scleroderma
53
Sjogren syndrome
93
Primary biliary cholangitis
107
Juvenile idiopathic arthritis
162
Pemphigoid
265
Lipodystrophy
269
Pyogenic arthritis
325
Hereditary autoinflammatory syndrome
2
JAK2
💬
2. JAK2
×
Name
Full Name
JAK2
Janus kinase 2
[24]
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
Chemokine signaling pathway
,
PI3K-Akt signaling pathway
,
Necroptosis
,
Signaling pathways regulating pluripotency of stem cells
,
JAK-STAT signaling pathway
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
Cholinergic synapse
,
Prolactin signaling pathway
,
Adipocytokine signaling pathway
,
AGE-RAGE signaling pathway in diabetic complications
,
Growth hormone synthesis, secretion and action
,
Leishmaniasis
,
Toxoplasmosis
,
Tuberculosis
,
Hepatitis B
,
Influenza A
,
Kaposi sarcoma-associated herpesvirus infection
,
Herpes simplex virus 1 infection
,
Pathways in cancer
,
Chemical carcinogenesis - receptor activation
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
Lipid and atherosclerosis
[24]
EGFR tyrosine kinase inhibitor resistance
,
Chemokine signaling pathway
,
PI3K-Akt signaling path
...
Baricitinib
Baricitinib
💬
2. JAK2
×
Name
Other Names
Baricitinib
Baricitinib (JAN/USAN/INN)
Olumiant (TN)
OTHER BARICITINIB
Baricitinib
[13]
2
2
,
41
,
46
,
49
,
50
,
51
,
53
,
93
,
107
,
162
,
265
,
269
,
325
💬
2. JAK2
×
Disease ID
Name
2
Amyotrophic lateral sclerosis
41
Giant cell arteritis
46
Malignant rheumatoid arthritis
49
Systemic lupus erythematosus
50
Dermatomyositis
51
Scleroderma
53
Sjogren syndrome
93
Primary biliary cholangitis
107
Juvenile idiopathic arthritis
162
Pemphigoid
265
Lipodystrophy
269
Pyogenic arthritis
325
Hereditary autoinflammatory syndrome